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Synthetic aroma chemicals

(+)-Sclareolide

Also known as Sclareolide, 12-Norambreinolide, (3aR)-(+)-Sclareolide

CAS 564-20-5Formula C16H26O2Molar mass 250.38 g/molEC 209-269-0
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(+)-Sclareolide chemical structure, C16H26O2, CAS 564-20-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
564-20-5
Formula
C16H26O2
Molar mass
250.38 g/mol
EC number
209-269-0
HS code
293220
Category
Synthetic aroma chemicals

What is (+)-Sclareolide?

Plain description, key identifiers and synonyms

Norambreinolide is a naphthofuran.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyl-1,4,5,5a,7,8,9,9b-octahydrobenzo[e][1]benzofuran-2-one
CAS number
564-20-5 CAS number cross-checked
EC number
209-269-0
Molecular formula
C16H26O2
UNII
37W4O0O6E6
MDL number
MFCD00134168
INCI name
SCLAREOLIDE
InChIKey
IMKJGXCIJJXALX-SHUKQUCYSA-N
InChI
InChI=1S/C16H26O2/c1-14(2)7-5-8-15(3)11(14)6-9-16(4)12(15)10-13(17)18-16/h11-12H,5-10H2,1-4H3/t11-,12+,15-,16+/m0/s1
Canonical SMILES
CC1(C)CCCC2(C)C1CCC1(C)OC(=O)CC12
Isomeric SMILES
C[C@]12CCCC([C@@H]1CC[C@@]3([C@@H]2CC(=O)O3)C)(C)C

Synonyms

  • Sclareolide
  • 12-Norambreinolide
  • (3aR)-(+)-Sclareolide
  • Norambreinolide
  • Clareolide
  • (3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyldecahydronaphtho[2,1-b]furan-2(1H)-one
  • (3aR,5aS,9aS,9bR)-3a,6,6,9a-Tetramethyldecahydronaphtho[2,1-b]furan-2(3aH)-one
  • (3aR,5aS,9aS,9bR)-Decahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan-2(1H)-one
  • (3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyl-1,4,5,5a,7,8,9,9b-octahydrobenzo[e][1]benzofuran-2-one
  • Decahydrotetramethylnaphthofuranone
  • (3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyl-1,4,5,5a,7,8,9,9b-octahydrobenzo[e]benzofuran-2-one
  • Norambreinolide, (+)-
  • (3aR)-(+)-Sclareolide, (+)-12-Norambreinolide, Decahydrotetramethylnaphthofuranone
  • Naphtho(2,1-b)furan-2(1H)-one, decahydro-3a,6,6,9a-tetramethyl-, (3aR,5aS,9aS,9bR)-
  • Sclareolide, 97%
  • Clary sage lactone
  • (3a,R)-(+)-Sclareolide
  • (3aR)-(+)-Sclareolide, 97%
  • (3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyl-dodecahydronaphtho[2,1-b]furan-2-one
  • 3a,4,5,5aalpha,6,7,8,9,9a,9balpha-decahydro-3abeta,6,6,9abeta-tetramethylnaphtho(2,1-b)furan-2(1H)-one
  • Naphtho(2,1-b)furan-2(1H)-one, 3a,4,5,5aalpha,6,7,8,9,9a,9balpha-decahydro-3abeta,6,6,9abeta-tetramethyl-
  • Naphtho(2,1-b)furan-2(1H)-one, decahydro-3a,6,6,9a-tetramethyl-, (3aR-(3aalpha,5abeta,9aalpha,9bbeta))-
  • (3aR)-(+)-Sclareolide, analytical standard
  • (3aR)-(+)-Sclareolide, natural, 97%, FG
  • (3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyl-1,4,5,5a,7,8,9,9b-octahydrobenzo[e][1]benzouran-2-one
Show all 26 synonyms
  • (3AR-(3aalpha,5abeta,9aalpha,9bbeta))decahydro-3a,6,6,9a-tetramethylnaphth(2,1-b)furan-2(1H)-one

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
250.38 g/molcalc.
Exact mass
250.1933 Dacalc.
LogP (octanol/water)
3.93calc.
Topological polar surface area
26.3 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
0calc.
Heavy atoms
18calc.
Rings
3calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.94calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CC2C(CCC3CCCCC32)O1

O=C1CC2C(CCC3CCCCC32)O1

3 rings, 14 atoms.

2 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

(+)-Sclareolide suppliers

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All 22 suppliers
22 of 22 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

22 suppliers in 5 countries

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(+)-Sclareolide price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name SCLAREOLIDE(fragrance, skin conditioning, perfuming)

Functional uses

  • Deodorizer
  • Flavouring and nutrient
  • Fragrance
  • Softener and conditioner

Cosmetic functions

  • Fragrance
  • Perfuming
  • Skin conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code (+)-Sclareolide is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for (+)-Sclareolide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about (+)-Sclareolide, based on the data on this page

What is (+)-Sclareolide?

Norambreinolide is a naphthofuran.

What is the CAS number of (+)-Sclareolide?

The CAS registry number of (+)-Sclareolide is 564-20-5.

What is the molecular formula and weight of (+)-Sclareolide?

The molecular formula of (+)-Sclareolide is C16H26O2 and its molar mass is 250.38 g/mol.

What is (+)-Sclareolide used for?

Known uses and roles of (+)-Sclareolide include skin conditioning agents in cosmetics and personal care, fragrance ingredients in cosmetics and personal care, fragrance ingredients in flavors and fragrances, esters and lactones in flavors and fragrances, fragrance and 5 more.

Is (+)-Sclareolide hazardous?

No GHS hazard classification for (+)-Sclareolide is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of (+)-Sclareolide?

(+)-Sclareolide is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy (+)-Sclareolide?

CompoundList lists 22 suppliers of (+)-Sclareolide in China, United States, Canada, Belgium and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy (+)-Sclareolide in India?

1 supplier in India list (+)-Sclareolide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of (+)-Sclareolide?

Suppliers quote (+)-Sclareolide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle (+)-Sclareolide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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