Sennosides
Also known as Glysennid, Laxative, Sennoside Ca
Key facts
What buyers check first
- CAS number
- 85085-71-8
- Formula
- C42H38O20
- Molar mass
- 862.75 g/mol
- EC number
- 208-238-9
- HS code
- 293299
- Category
- Respiratory, allergy and digestive drugs
What is Sennosides?
Plain description, key identifiers and synonyms
Laxative is synthetic compounds or mixtures administered orally or rectally with laxative activity. A laxative preparation is used to promote bowel movement to treat constipation or to clean the colon for rectal and bowel examinations. There are different types of laxatives that differ in mechanism of action and potency, including the bulk-producing agents, stool softeners, lubricants, hydrating agents, stimulants, saline laxatives and hyperosmotic agents.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 9-[2-carboxy-4-hydroxy-10-oxo-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid
- CAS number
- 85085-71-8Other or deprecated CAS: 517-43-1, 62211-03-4, 66575-30-2, 81-27-6
- EC numbers
- 208-238-9, 263-461-9, 285-393-9, 805-136-1
- Molecular formula
- C42H38O20
- UNII
- 9VK7V8762D
- MDL number
- MFCD32068370
- INCI name
- CASSIA ITALICA LEAF EXTRACT, CASSIA ITALICA LEAF POWDER
- InChIKey
- IPQVTOJGNYVQEO-UHFFFAOYSA-N
- InChI
- InChI=1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)
- SMILES (canonical and isomeric)
- C1=CC2=C(C(=C1)OC3C(C(C(C(O3)CO)O)O)O)C(=O)C4=C(C2C5C6=C(C(=CC=C6)OC7C(C(C(C(O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)C(=O)O
Synonyms
- Glysennid
- Laxative
- Sennoside Ca
- Colonorm
- Nytilax
- Sankaijo
- Exchange select
- Docuset Sodium
- Laxative Pills
- Laxative Senna
- Senna Glycoside
- Colistat Plus
- Gentle Nature
- Senna Liquid
- Colon Detox
- Geri-kot
- Senna Plus
- Senna-Tabs
- Nature's Remedy
- Senna Lax
- Senna-Doc
- Senokot-S
- Senna S Orange
- Senna S Laxative
- Chocolate Laxative
Show all 39 synonymsShow fewer synonyms
- Senna S
- Vegetable Laxative
- Senna UD
- Plus Pharma Senna
- Sennoside 25 mg
- Chocolated Laxative
- Sennosides 15 mg
- Sennosides 25 mg
- Sennosides 8.6mg
- CVS Senna Laxative
- Laxative Preparation
- Super Colon Cleanse
- Caremotion
- Docuzen
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 862.75 g/molcalc.Computed value |
|---|---|
| Exact mass | 862.1956 Dacalc.Computed value |
| LogP (octanol/water) | -1.1calc.Computed value |
| Topological polar surface area | 348 Ųcalc.Computed value |
| Hydrogen bond donors | 12calc.Computed value |
| Hydrogen bond acceptors | 18calc.Computed value |
| Rotatable bonds | 9calc.Computed value |
| Heavy atoms | 62calc.Computed value |
| Rings | 8calc.Computed value |
| Aromatic rings | 4calc.Computed value |
| Fraction sp3 carbons | 0.33calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 12calc.Computed value |
| Lipinski rule of five | Fails (3 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=C1c2ccccc2C(C2c3ccccc3C(=O)c3c(OC4CCCCO4)cccc32)c2cccc(OC3CCCCO3)c21
8 rings, 44 atoms.
19 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H317May cause an allergic skin reaction.
- H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary statements (15)
- P233Keep container tightly closed.
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P271Use only outdoors or in a well-ventilated area.
- P272Contaminated work clothing should not be allowed out of the workplace.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P284In case of inadequate ventilation wear respiratory protection.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P333 + P317If skin irritation or rash occurs: Get medical help.
- P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P403Store in a well-ventilated place.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidSennosides suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- India, Madurai ManufacturerUnclaimed profileSennosidesGrade Pharma (USP)Price on request
- ManufacturerUnclaimed profileSennosidesGrade, purity and minimum order on requestPrice on request
- Japan, Hida ManufacturerUnclaimed profileSennosides calciumGrade, purity and minimum order on requestPrice on request
- Japan, Osaka ManufacturerUnclaimed profileSennosidesGrade, purity and minimum order on requestPrice on request
- Price on request
- India, Faridabad ManufacturerUnclaimed profileSennosidesGrade, purity and minimum order on requestPrice on request
- Japan, Hida-shi ManufacturerUnclaimed profileSennosidesGrade, purity and minimum order on requestPrice on request
- India, Alwar ManufacturerUnclaimed profileSennosidesGrade, purity and minimum order on requestPrice on request
- India, Udham Singh Nagar ManufacturerUnclaimed profileSennosidesGrade, purity and minimum order on requestPrice on request
- United States, San DiegoUnclaimed profileSennosidesGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
45 suppliers in 12 countries
- United States15
- China12
- India5
- Japan3
- United Kingdom2
- Germany1
- and 6 more countries
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Sennosides price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Use classes: Cosmetics.
Industries and functions
Cosmetic ingredient, INCI name CASSIA ITALICA LEAF EXTRACT(skin conditioning)
Pharmacological actions
- Laxatives
Cosmetic functions
- Skin conditioning
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- EU cosmetic ingredient inventory
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Sennosides is traded under.
Heterocyclic compounds with oxygen hetero-atom(s) only, other
- China28.9%
- Switzerland * partner reported12.7%
- Germany7.8%
- United States49.7%
- China11.9%
- India * partner reported3.3%
* Partner reported figures, a lower bound.
The HS code shown for Sennosides is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Sennosides, based on the data on this page
What is Sennosides?
What is the CAS number of Sennosides?
What is the molecular formula and weight of Sennosides?
What is Sennosides used for?
Is Sennosides hazardous?
What is the HS code of Sennosides?
Where can I buy Sennosides?
Where can I buy Sennosides in India?
What is the price of Sennosides?
Guides for buyers
Practical guides that help when you source, ship or handle Sennosides
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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