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Central nervous system drugs

Sertraline

Also known as (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, (+)-Sertraline, Sertralina

CAS 79617-96-2Formula C17H17Cl2NMolar mass 306.24 g/molEC 616-708-3
GHS signal word: Warning. Pictograms: Harmful or irritant, Hazardous to the environment 80 suppliers listed Drug substance
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Sertraline chemical structure, C17H17Cl2N, CAS 79617-96-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
79617-96-2
Formula
C17H17Cl2N
Molar mass
306.24 g/mol
EC number
616-708-3
HS code
292149
Category
Central nervous system drugs

What is Sertraline?

Plain description, key identifiers and synonyms

Sertraline is a member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder. It has a role as an antidepressant and a serotonin uptake inhibitor. It is a dichlorobenzene, a member of tetralins and a secondary amino compound. It is a conjugate base of a sertraline(1+). It derives from a hydride of a tetralin.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
CAS number
79617-96-2 CAS number cross-checkedOther or deprecated CAS: 219736-80-8, 79617-95-1
EC numbers
616-708-3, 642-001-4
Molecular formula
C17H17Cl2N
UNII
AM64MTB95A, QUC7NX6WMB
MDL number
MFCD00865372
InChIKey
VGKDLMBJGBXTGI-SJCJKPOMSA-N
InChI
InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17-/m0/s1
Canonical SMILES
CNC1CCC(c2ccc(Cl)c(Cl)c2)c2ccccc21
Isomeric SMILES
CN[C@H]1CC[C@H](C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl

Synonyms

  • (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
  • (+)-Sertraline
  • Sertralina
  • Sertralinum
  • cis-(+)-sertraline
  • Cp 51974
  • (1S,4S)-sertraline
  • (1S-cis)-1,2,3,4-Tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
  • 1-Naphthalenamine, 1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-, (1S-cis)-
  • Altruline
  • Besitran
  • Apo Sertraline
  • Gen Sertraline
  • Novo Sertraline
  • ratio Sertraline
  • Rhoxal sertraline
  • 1-Naphthalenamine,1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-, (1S-cis)-
  • (R,R)-Sertraline
  • Sertraline (INN)
  • C17H17Cl2N
  • (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-tetralin-1-amine
  • TBA-2010_Sertraline_1
  • cis-sertraline
  • 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, (1S,4S)-
  • SRE
Show all 29 synonyms
  • Sertraline Free Base
  • (+/-)-sertraline
  • (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, hydrochloride
  • Sertraline, (+/-)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
306.24 g/molcalc.
Exact mass
305.0738 Dacalc.
LogP (octanol/water)
5.18calc.
Topological polar surface area
12.03 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
2calc.
Heavy atoms
20calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.29calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(C2CCCc3ccccc32)cc1

c1ccc(C2CCCc3ccccc32)cc1

3 rings, 16 atoms, the 1-Phenyl-1,2,3,4-tetrahydronaphthalene ring system.

178 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H302Harmful if swallowed.
  • H411Toxic to aquatic life with long lasting effects.
Precautionary statements (7)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P273Avoid release to the environment.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Sertraline suppliers

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All 80 suppliers
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Where suppliers are based

80 suppliers in 19 countries

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Sertraline price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

As selective seratonin reuptake inhibitor for treatment of depression & obsessive-compulsive disorder, perhaps treatment of obesity & reduction of alcohol craving.

For treatment of panic disorder and posttraumatic stress disorder.

Use classes: Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Antidepressive Agents
  • Selective Serotonin Reuptake Inhibitors

Roles

  • antidepressant
  • central nervous system drug
  • neurotransmitter agent
  • pharmaceutical
  • psychotropic drug
  • serotonergic drug
  • serotonin uptake inhibitor

Functional uses

  • Pharmaceutical

Pharmacology

Sertraline is a Serotonin Reuptake Inhibitor. The mechanism of action of sertraline is as a Serotonin Uptake Inhibitor and Cytochrome P450 2D6 Inhibitor.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Sertraline is traded under.

HS 2921.49Indicative HS code

Aromatic monoamines and their derivatives, salts thereof, other

World exports in 2024
$1.14B
+5.6% vs 2023, imports $1.06B
2019 to 2024
Top exporters
  1. Germany23.3%
  2. China19.4%
  3. Singapore14.6%
Top importers
  1. Belgium15.9%
  2. South Korea15.0%
  3. Germany12.8%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Sertraline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Sertraline, based on the data on this page

What is Sertraline?

Sertraline is a member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer).

What is the CAS number of Sertraline?

The CAS registry number of Sertraline is 79617-96-2. Other or deprecated CAS numbers: 219736-80-8, 79617-95-1.

What is the molecular formula and weight of Sertraline?

The molecular formula of Sertraline is C17H17Cl2N and its molar mass is 306.24 g/mol.

What is Sertraline used for?

As selective seratonin reuptake inhibitor for treatment of depression & obsessive-compulsive disorder, perhaps treatment of obesity & reduction of alcohol craving. For treatment of panic disorder and posttraumatic stress disorder. Use classes: Pharmaceuticals.

Is Sertraline hazardous?

Sertraline carries the GHS signal word "Warning". Main hazards: harmful if swallowed, toxic to aquatic life with long lasting effects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Sertraline?

Sertraline is usually classified under HS code 292149 (Aromatic monoamines and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Sertraline?

CompoundList lists 80 suppliers of Sertraline in India, United States, China, Germany and 15 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Sertraline in India?

21 suppliers in India list Sertraline on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Sertraline?

Suppliers quote Sertraline on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Sertraline

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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