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Central nervous system drugs

Sevoflurane

Also known as 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane, Sevofluran, Ultane

CAS 28523-86-6Formula C4H3F7OMolar mass 200.05 g/molEC 643-089-7
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard 99 suppliers listed Drug substance
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Sevoflurane chemical structure, C4H3F7O, CAS 28523-86-6
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Liquid
Boiling point
58.1 to 58.2
Density
Relative density of the vapour/air-mixture at 20 °C (air = 1): 1.1
HS code
290919
Category
Central nervous system drugs
Illustrative photo, 200 litre blue HDPE drums of liquid in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Sevoflurane?

Plain description, key identifiers and synonyms

Sevoflurane is an ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups. It has a role as a central nervous system depressant, an inhalation anaesthetic and a platelet aggregation inhibitor. It is an ether and an organofluorine compound. It is functionally related to a 2-methoxypropane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane
CAS number
28523-86-6 CAS number cross-checkedOther or deprecated CAS: 1173021-96-9
EC number
643-089-7
Molecular formula
C4H3F7O
UNII
38LVP0K73A
MDL number
MFCD00153189
InChIKey
DFEYYRMXOJXZRJ-UHFFFAOYSA-N
InChI
InChI=1S/C4H3F7O/c5-1-12-2(3(6,7)8)4(9,10)11/h2H,1H2
SMILES (canonical and isomeric)
C(OC(C(F)(F)F)C(F)(F)F)F

Synonyms

  • 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane
  • Sevofluran
  • Ultane
  • Sevorane
  • Sevoflurano
  • Sojourn
  • sevoflo
  • Sevofluranum
  • Propane, 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)-
  • Sevocalm
  • Petrem
  • Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
  • Ether, fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl-
  • fluoromethyl hexafluoroisopropyl ether
  • Sevospire
  • FlurovessTM
  • fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
  • Sevoflurane Bostonbio
  • Fluoromethyl 1,1,1,3,3,3-Hexafluoroisopropyl Ether
  • 1H,1H,3H-Perfluoro(3-methyl-2-oxabutane)
  • Sevofrane
  • Propane,1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)-
  • Bax 3084
  • Sevoflurane-d3, Fluoromethyl 1,1,1,3,3,3-hexafluoro-2-propyl ether-d3, Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether-d3
  • Ultane (TN)
Show all 29 synonyms
  • Sevoflurane CRS
  • SevofluraneFluoromethyl
  • Fluoromethyl 2H-hexafluoroprop-2-yl ether
  • (CF3)2CHOCH2F

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Liquidexp.
Boiling point
58.1 to 58.2exp.
Density
Relative density of the vapour/air-mixture at 20 °C (air = 1): 1.1exp.
Vapour pressure
VP: 200 torr at 25 °C, 160 torrexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
200.05 g/molcalc.
Exact mass
200.0072 Dacalc.
LogP (octanol/water)
2.42calc.
Topological polar surface area
9.23 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
2calc.
Heavy atoms
12calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H336May cause drowsiness or dizziness.
  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (18)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Sevoflurane suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 99 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

99 suppliers in 18 countries

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Sevoflurane price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Animal Drugs.

Pharmacological actions

  • Anesthetics, Inhalation
  • Platelet Aggregation Inhibitors

Roles

  • anaesthetic
  • analgesic
  • anti-inflammatory agent
  • anti-obesity agent
  • antidote
  • antimicrobial agent
  • antineoplastic agent
  • antiviral agent
  • anxiolytic drug
  • cardiovascular drug
  • central nervous system depressant
  • central nervous system drug
  • general anaesthetic
  • hematologic agent
  • inhalation anaesthetic
  • neuroprotective agent
  • pharmaceutical
  • platelet aggregation inhibitor
  • protective agent
  • psychotropic drug
  • renoprotective agent
  • tranquilizing drug

Pharmacology

Sevoflurane is a General Anesthetic. The physiologic effect of sevoflurane is by means of General Anesthesia.

How it is made

Preparation: B.M. Regan, J.C. Longstreet, DE 1954268, eidem, US 3689571 (1970, 1972 both to Baxter Labs.)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Sevoflurane is traded under.

HS 2909.19Indicative HS code

Acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives…

World exports in 2024
$10.2B
−8.7% vs 2023, imports $10.4B
2019 to 2024
Top exporters
  1. United States32.0%
  2. China22.3%
  3. Saudi Arabia12.9%
Top importers
  1. Singapore16.5%
  2. Mexico14.8%
  3. Japan14.8%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Sevoflurane is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Sevoflurane, based on the data on this page

What is Sevoflurane?

Sevoflurane is an ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups. It has a role as a central nervous system depressant, an inhalation anaesthetic and a platelet aggregation inhibitor. It is an ether and an organofluorine compound.

What is the CAS number of Sevoflurane?

The CAS registry number of Sevoflurane is 28523-86-6. Other or deprecated CAS numbers: 1173021-96-9.

What is the molecular formula and weight of Sevoflurane?

The molecular formula of Sevoflurane is C4H3F7O and its molar mass is 200.05 g/mol.

What is Sevoflurane used for?

Use classes: Animal Drugs.

Is Sevoflurane hazardous?

Sevoflurane carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause drowsiness or dizziness. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Sevoflurane?

Sevoflurane is usually classified under HS code 290919 (Acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Sevoflurane?

CompoundList lists 99 suppliers of Sevoflurane in China, United States, India, United Kingdom and 14 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Sevoflurane in India?

8 suppliers in India list Sevoflurane on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Sevoflurane?

Suppliers quote Sevoflurane on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Sevoflurane

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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