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Screening compounds

Sivifene

Also known as Sivifeno, 4,4'-Dihydroxybenzophenone 2,4-dinitrophenylhydrazone, sivifenum

CAS 2675-35-6Formula C19H14N4O6Molar mass 394.34 g/mol
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Sivifene chemical structure, C19H14N4O6, CAS 2675-35-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
2675-35-6
Formula
C19H14N4O6
Molar mass
394.34 g/mol
HS code
292800
Category
Screening compounds

What is Sivifene?

Plain description, key identifiers and synonyms

Sivifene is the phenylhydrazone 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone formulated as a topical agent with immunomodulating and potential antineoplastic activities. Applied topically as a gel, sivifene may stimulate a local immune response against human papillomavirus (HPV)-induced cervical intraepithelial neoplasia (CIN).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-[N-(2,4-dinitroanilino)-C-(4-hydroxyphenyl)carbonimidoyl]phenol
CAS number
2675-35-6 CAS number cross-checked
Molecular formula
C19H14N4O6
UNII
XAV05295I5
InChIKey
YOQPCWIXYUNEET-UHFFFAOYSA-N
InChI
InChI=1S/C19H14N4O6/c24-15-6-1-12(2-7-15)19(13-3-8-16(25)9-4-13)21-20-17-10-5-14(22(26)27)11-18(17)23(28)29/h1-11,20,24-25H
SMILES (canonical and isomeric)
C1=CC(=CC=C1C(=NNC2=C(C=C(C=C2)[N+](=O)[O-])[N+](=O)[O-])C3=CC=C(C=C3)O)O

Synonyms

  • Sivifeno
  • 4,4'-Dihydroxybenzophenone 2,4-dinitrophenylhydrazone
  • sivifenum
  • Aryl Hydrazone A-007 Gel
  • Bis(4-hydroxyphenyl)methanone 2-(2,4-dinitrophenyl)hydrazone
  • 4-((2-(2,4-dinitrophenyl)hydrazin-1-ylidene)(4-hydroxyphenyl)methyl)phenol
  • 4,4'-Dihydroxybenzophenone-2,4-dinitrophenyl-hydrazone
  • Methanone, bis(4-hydroxyphenyl)-, (2,4-dinitrophenyl)hydrazone
  • 4-[N-(2,4-dinitroanilino)-C-(4-hydroxyphenyl)carbonimidoyl]phenol
  • 4,4'-{[2-(2,4-Dinitrophenyl)hydrazinylidene]methylene}diphenol
  • 4,4'-((2-(2,4-Dinitrophenyl)hydrazinylidene)methylene)diphenol
  • Sivifene (USAN/INN)
  • 4-[[2-(2,4-dinitrophenyl)hydrazinyl]-(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one
  • bis(4-hydroxyphenyl)methanone (2,4-dinitrophenyl)hydrazone
  • 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
394.34 g/molcalc.
Exact mass
394.0913 Dacalc.
LogP (octanol/water)
3.78calc.
Topological polar surface area
151.1 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
8calc.
Rotatable bonds
6calc.
Heavy atoms
29calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(NN=C(c2ccccc2)c2ccccc2)cc1

c1ccc(NN=C(c2ccccc2)c2ccccc2)cc1

3 rings, 21 atoms, the Benzophenone phenylhydrazone ring system.

21 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Sivifene suppliers

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Sivifene price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antineoplastic agent
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Sivifene is traded under.

HS 2928.00Indicative HS code

Organic derivatives of hydrazine or of hydroxylamine

World exports in 2024
$1.38B
−9.0% vs 2023, imports $1.52B
2019 to 2024
Top exporters
  1. Switzerland * partner reported44.0%
  2. China18.4%
  3. Italy9.4%
Top importers
  1. Brazil21.8%
  2. United States12.8%
  3. Italy10.8%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Sivifene is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Sivifene, based on the data on this page

What is Sivifene?

Sivifene is the phenylhydrazone 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone formulated as a topical agent with immunomodulating and potential antineoplastic activities.

What is the CAS number of Sivifene?

The CAS registry number of Sivifene is 2675-35-6.

What is the molecular formula and weight of Sivifene?

The molecular formula of Sivifene is C19H14N4O6 and its molar mass is 394.34 g/mol.

What is Sivifene used for?

Known uses and roles of Sivifene include building blocks in research and laboratory, screening compounds in research and laboratory, antineoplastic agent and pharmaceutical.

Is Sivifene hazardous?

No GHS hazard classification for Sivifene is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Sivifene?

Sivifene is usually classified under HS code 292800 (Organic derivatives of hydrazine or of hydroxylamine). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Sivifene?

Post a free request on CompoundList and suppliers of Sivifene will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Sivifene?

Suppliers quote Sivifene on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Sivifene

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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