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Humectants

Sodium pidolate

Also known as Sodium L-pyroglutamate, Sodium pyroglutamate, L-Proline, 5-oxo-, monosodium salt

CAS 28874-51-3Formula C5H6NNaO3Molar mass 151.10 g/molEC 249-277-1
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Sodium pidolate chemical structure, C5H6NNaO3, CAS 28874-51-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
28874-51-3
Formula
C5H6NNaO3
Molar mass
151.10 g/mol
EC number
249-277-1
HS code
293379
Category
Humectants

What is Sodium pidolate?

Plain description, key identifiers and synonyms

Sodium pidolate is a chemical substance with the molecular formula C5H6NNaO3 and a molar mass of 151.10 g/mol. Its CAS registry number is 28874-51-3. The IUPAC name is sodium (2S)-5-oxopyrrolidine-2-carboxylate.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
sodium (2S)-5-oxopyrrolidine-2-carboxylate
CAS number
28874-51-3 CAS number cross-checkedOther or deprecated CAS: 54571-67-4
EC number
249-277-1
Molecular formula
C5H6NNaO3
UNII
1V74VH163T
MDL number
MFCD01749005
INCI name
SODIUM PCA
InChIKey
CRPCXAMJWCDHFM-DFWYDOINSA-M
InChI
InChI=1S/C5H7NO3.Na/c7-4-2-1-3(6-4)5(8)9;/h3H,1-2H2,(H,6,7)(H,8,9);/q;+1/p-1/t3-;/m0./s1
Canonical SMILES
O=C1CCC(C(=O)[O-])N1.[Na+]
Isomeric SMILES
C1CC(=O)N[C@@H]1C(=O)[O-].[Na+]

Synonyms

  • Sodium L-pyroglutamate
  • Sodium pyroglutamate
  • L-Proline, 5-oxo-, monosodium salt
  • L-5-Oxoproline monosodium salt
  • Sodium pyrrolidone-5-carboxylate
  • 5-Oxo-L-proline monosodium salt
  • Sodium L-pyrrolidonecarboxylate
  • Proline, 5-oxo-, monosodium salt, L-
  • PDSI 101
  • L-Sodium pidolate
  • Pidolate Sodium
  • 2-Pyrrolidone-5-Carboxylic Acid Sodium Salt
  • Sodium 5-oxo-L-prolinate
  • Proline, 5-oxo-, monosodium salt
  • Sodium (S)-5-oxopyrrolidine-2-carboxylate
  • Sodium L-Pyroglutamate (Technical Grade)
  • sodium, (2S)-5-oxopyrrolidine-2-carboxylate
  • Sodium (S)-5-oxopyrrolidine-2-carboxylate (50% in H2O)
  • Sodium L-pyroglutama
  • Sodium L-pyroglutamateE
  • L-Pyroglutamic acid sodium
  • MSK9039Na
  • MSK9039Na-100W
  • Sodium (2S)-5-oxopyrrolidine-2-carboxylate
  • Sodium L-pyroglutamateE Solution in Water, 100ug/mL

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
151.10 g/molcalc.
Exact mass
151.0245 Dacalc.
LogP (octanol/water)
-4.98calc.
Topological polar surface area
69.23 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
1calc.
Heavy atoms
10calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.6calc.
Formal charge
0calc.
Stereocentres
1calc.
Components
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCCN1

O=C1CCCN1

1 ring, 6 atoms, the 2-Pyrrolidone ring system.

3,308 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Sodium pidolate suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 11 suppliers
11 of 11 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

11 suppliers in 4 countries

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Sodium pidolate price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name SODIUM PCA(antistatic, hair conditioning, humectant, skin conditioning)

Functional uses

  • Anti-static agent
  • Humectant
  • Softener and conditioner

Cosmetic functions

  • Antistatic
  • Hair conditioning
  • Humectant
  • Skin conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce, Regulatory flags: Added by a premanufacture notice

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Sodium pidolate is traded under.

HS 2933.79Indicative HS code

Lactams, other lactams

World exports in 2024
$16.2B
−64.4% vs 2023, imports $15.4B
2019 to 2024
Top exporters
  1. Ireland37.0%
  2. France * partner reported15.6%
  3. Spain11.3%
Top importers
  1. Germany27.8%
  2. Ireland18.9%
  3. Panama * partner reported12.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Sodium pidolate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Sodium pidolate, based on the data on this page

What is Sodium pidolate?

Sodium pidolate is a chemical substance with the molecular formula C5H6NNaO3 and a molar mass of 151.10 g/mol. Its CAS registry number is 28874-51-3. The IUPAC name is sodium (2S)-5-oxopyrrolidine-2-carboxylate.

What is the CAS number of Sodium pidolate?

The CAS registry number of Sodium pidolate is 28874-51-3. Other or deprecated CAS numbers: 54571-67-4.

What is the molecular formula and weight of Sodium pidolate?

The molecular formula of Sodium pidolate is C5H6NNaO3 and its molar mass is 151.10 g/mol.

What is Sodium pidolate used for?

Known uses and roles of Sodium pidolate include humectants in cosmetics and personal care, skin conditioning agents in cosmetics and personal care, hair conditioning agents in cosmetics and personal care, antistatic, hair conditioning and 4 more.

Is Sodium pidolate hazardous?

No GHS hazard classification for Sodium pidolate is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Sodium pidolate?

Sodium pidolate is usually classified under HS code 293379 (Lactams, other lactams). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Sodium pidolate?

CompoundList lists 11 suppliers of Sodium pidolate in China, Brazil, India and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Sodium pidolate in India?

1 supplier in India list Sodium pidolate on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Sodium pidolate?

Suppliers quote Sodium pidolate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Sodium pidolate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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