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Respiratory, allergy and digestive drugs

Sofalcone

Also known as Solon, Sofalcona, Sofalconum

CAS 64506-49-6Formula C27H30O6Molar mass 450.53 g/mol
3 suppliers listed
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Sofalcone chemical structure, C27H30O6, CAS 64506-49-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
64506-49-6
Formula
C27H30O6
Molar mass
450.53 g/mol
HS code
291899
Category
Respiratory, allergy and digestive drugs

What is Sofalcone?

Plain description, key identifiers and synonyms

Sofalcone is a member of the class of chalcones that is benzene in which the hydrogens at positions 1,2 and 5 are replaced by carboxymethoxy, (1E)-1-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}-3-oxoprop-1-en-3-yl, and (3-methylbut-2-en-1-yl)oxy groups, respectively. It is a gastrointestinal drug currently used for treatment of gastritis and gastric ulcers in Japan and South Korea. It has a role as an antibacterial agent, an anti-ulcer drug, a gastrointestinal drug and a plant metabolite. It is a member of chalcones, a monocarboxylic acid and an aromatic ether.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-[5-(3-methylbut-2-enoxy)-2-[(E)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-2-enoyl]phenoxy]acetic acid
CAS number
64506-49-6 CAS number cross-checkedOther or deprecated CAS: 153175-87-2
Molecular formula
C27H30O6
UNII
2B668TJX8E
MDL number
MFCD00868207
InChIKey
GFWRVVCDTLRWPK-KPKJPENVSA-N
InChI
InChI=1S/C27H30O6/c1-19(2)13-15-31-22-8-5-21(6-9-22)7-12-25(28)24-11-10-23(32-16-14-20(3)4)17-26(24)33-18-27(29)30/h5-14,17H,15-16,18H2,1-4H3,(H,29,30)/b12-7+
SMILES
CC(=CCOC1=CC=C(C=C1)/C=C/C(=O)C2=C(C=C(C=C2)OCC=C(C)C)OCC(=O)O)C

Synonyms

  • Solon
  • Sofalcona
  • Sofalconum
  • (5-((3-Methyl-2-butenyl)oxy)-2-(p-((3-methyl-2-butenyl)oxy)cinnamoyl)phenoxy)acetic acid
  • Acetic acid, 2-(5-((3-methyl-2-buten-1-yl)oxy)-2-((2E)-3-(4-((3-methyl-2-buten-1-yl)oxy)phenyl)-1-oxo-2-propen-1-yl)phenoxy)-
  • 2-(5-((3-methylbut-2-en-1-yl)oxy)-2-((2E)-3-(4-((3-methylbut-2-en-1-yl)oxy)phenyl)prop-2-enoyl)phenoxy)acetic acid
  • 2-{5-[(3-methylbut-2-en-1-yl)oxy]-2-[(2E)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl]phenoxy}acetic acid
  • 2-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)chalcone
  • Sofalcone (JAN)
  • 2-[5-(3-methylbut-2-enoxy)-2-[(E)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-2-enoyl]phenoxy]acetic acid
  • (E)-2-(5-((3-Methylbut-2-en-1-yl)oxy)-2-(3-(4-((3-methylbut-2-en-1-yl)oxy)phenyl)acryloyl)phenoxy)acetic acid
  • 2-(5-((3-Methylbut-2-en-1-yl)oxy)-2-(3-(4-((3-methylbut-2-en-1-yl)oxy)phenyl)acryloyl)phenoxy)acetic acid
  • Isoprenyl chalcone
  • Acetic acid,[5-[(3-methyl-2-butenyl)oxy]-2-[3-[4-[(3-methyl-2-butenyl)oxy]phenyl]-1-oxo-2-propenyl]phenoxy]-
  • 2'-carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy) chalcone
  • ({5-[(3-methylbut-2-en-1-yl)oxy]-2-[(2E)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl]phenyl}oxy)acetic acid
  • {5-[(3-methylbut-2-en-1-yl)oxy]-2-[(2E)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl]phenoxy}acetic acid
  • Acetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]-
  • Solon (TN)
  • Tofalcone
  • Lavin
  • SU 88
  • Sofalcone (Standard)
  • 2'-Carboxymethoxy-4,4'-bis(3-methyl-2-butenyloxy)chalcone
  • US20250213569, Compound 68
Show all 28 synonyms
  • Acetic acid, (5((3-methyl-2-butenyl)oxy)-2-(3-(4-((3-methyl-2-butenyl)oxy)phenyl)-1-oxo-2-propenyl)phenoxy)-
  • 2-Carboxymethoxy-4,4-Bis(3-Methyl-2-Butenyloxy)Chalcone
  • 2'-carboxymethoxy-4,4'-bis(3-methylbut-2-enyloxy)chalcone sofalcone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
450.53 g/molcalc.
Exact mass
450.2042 Dacalc.
LogP (octanol/water)
5.74calc.
Topological polar surface area
82.06 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
12calc.
Heavy atoms
33calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.26calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(C=Cc1ccccc1)c1ccccc1

O=C(C=Cc1ccccc1)c1ccccc1

2 rings, 16 atoms.

2,316 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Sofalcone suppliers

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All 3 suppliers

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Where suppliers are based

3 suppliers in 3 countries

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Sofalcone price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Ulcer Agents

Roles

  • anti-ulcer drug
  • antibacterial agent
  • antimicrobial agent
  • eukaryotic metabolite
  • gastrointestinal drug
  • metabolite
  • pharmaceutical
  • plant metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Sofalcone is traded under.

HS 2918.99Indicative HS code

Carboxylic acids, with additional oxygen function (not alcohol, phenol, aldehyde or ketone)…

World exports in 2024
$1.46B
−1.1% vs 2023, imports $1.54B
2019 to 2024
Top exporters
  1. China40.0%
  2. India * partner reported26.6%
  3. Germany8.0%
Top importers
  1. United States25.6%
  2. Brazil6.7%
  3. Argentina5.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Sofalcone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Sofalcone, based on the data on this page

What is Sofalcone?

Sofalcone is a member of the class of chalcones that is benzene in which the hydrogens at positions 1,2 and 5 are replaced by carboxymethoxy, (1E)-1-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}-3-oxoprop-1-en-3-yl, and (3-methylbut-2-en-1-yl)oxy groups, respectively.

What is the CAS number of Sofalcone?

The CAS registry number of Sofalcone is 64506-49-6. Other or deprecated CAS numbers: 153175-87-2.

What is the molecular formula and weight of Sofalcone?

The molecular formula of Sofalcone is C27H30O6 and its molar mass is 450.53 g/mol.

What is Sofalcone used for?

Known uses and roles of Sofalcone include anti-ulcer drug, antibacterial agent, antimicrobial agent, eukaryotic metabolite, gastrointestinal drug and 4 more.

Is Sofalcone hazardous?

No GHS hazard classification for Sofalcone is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Sofalcone?

Sofalcone is usually classified under HS code 291899 (Carboxylic acids with additional oxygen function and their anhydrides, halides…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Sofalcone?

CompoundList lists 3 suppliers of Sofalcone in China, Japan and South Korea. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Sofalcone?

Suppliers quote Sofalcone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Sofalcone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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