Spiramycin I
Also known as Foromacidin A, Foromacidine A, Spiramycin A
Key facts
What buyers check first
- CAS number
- 24916-50-5
- Formula
- C43H74N2O14
- Molar mass
- 843.07 g/mol
- EC number
- 975-622-7
- HS code
- 293220
- Category
- Antibiotics and anti-infectives
What is Spiramycin I?
Plain description, key identifiers and synonyms
spiramycin I has been reported in Streptomyces ambofaciens.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
- CAS number
- 24916-50-5 CAS number cross-checked
- EC number
- 975-622-7
- Molecular formula
- C43H74N2O14
- UNII
- 033ECH6IFG
- InChIKey
- ACTOXUHEUCPTEW-CEUOBAOPSA-N
- InChI
- InChI=1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26-,27-,28+,29+,30+,31-,32+,34+,35+,36-,37-,38-,39+,40+,41+,42+,43-/m1/s1
- Canonical SMILES
- COC1C(O)CC(=O)OC(C)CC=CC=CC(OC2CCC(N(C)C)C(C)O2)C(C)CC(CC=O)C1OC1OC(C)C(OC2CC(C)(O)C(O)C(C)O2)C(N(C)C)C1O
- Isomeric SMILES
- C[C@@H]1C/C=C/C=C/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)O[C@H]4CC[C@@H]([C@H](O4)C)N(C)C
Synonyms
- Foromacidin A
- Foromacidine A
- Spiramycin A
- Spiramycin 1
- Demycarosylturimycin H
- Leucomycin V, 9-O-(5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl)-, (9(2R,5S,6R))-
- Leucomycin V, 9-O-((2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl)-
- Leucomycin V, 9-O-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]-
- Leucomycin v, 9-o-(5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl)-, (9(5S,6R))-
- Spiramycin base
- Spiramycin I (Contains up to 6% Spiramycin III)
- Rovamycin (TN)
- N-desmethyl-Spiramycin
- Spiramycin (Standard)
- Spiramycin I (Standard)
- Spiramycin I (>90%)
- Spiramycin (JAN/USAN/INN)
- US20240118263, Compound Spiramycin
- Spiramycin Solution in Methanol, 100ug/mL
- Spiramycin Solution in Methanol, 1000ug/mL
- Spiramycin I Solution in Methanol, 100ug/mL
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 843.07 g/molcalc.Computed value |
|---|---|
| Exact mass | 842.514 Dacalc.Computed value |
| LogP (octanol/water) | 2.33calc.Computed value |
| Topological polar surface area | 195.4 Ųcalc.Computed value |
| Hydrogen bond donors | 4calc.Computed value |
| Hydrogen bond acceptors | 16calc.Computed value |
| Rotatable bonds | 11calc.Computed value |
| Heavy atoms | 59calc.Computed value |
| Rings | 4calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.86calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 19calc.Computed value |
| Lipinski rule of five | Fails (2 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=C1CCCC(OC2CCC(OC3CCCCO3)CO2)CCCC(OC2CCCCO2)C=CC=CCCO1
4 rings, 38 atoms.
41 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H411Toxic to aquatic life with long lasting effects.
Precautionary statements (3)
- P273Avoid release to the environment.
- P391Collect spillage.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidSpiramycin I suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- Australia, SmithfieldUnclaimed profileSpiramycin IGrade, purity and minimum order on requestPrice on request
- United States, St. PaulUnclaimed profileSpiramycin IGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
2 suppliers in 2 countries
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Spiramycin I price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Industries and functions
Roles
- antibacterial agent
- antibacterial drug
- antiinfective agent
- antimicrobial agent
- antimicrobial drug
- bacterial metabolite
- metabolite
- pharmaceutical
- prokaryotic metabolite
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Spiramycin I is traded under.
Lactones
- United States14.2%
- India * partner reported13.5%
- Brazil8.5%
* Partner reported figures, a lower bound.
The HS code shown for Spiramycin I is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Related chemicals
Parent and salt forms, stereoisomers, similar structures and isomers
Stereoisomers and isotopic forms
Same connectivity, different stereochemistry or isotopes (same InChIKey skeleton)
![2-[(4R,5S,6S,7R,9R,10R,11Z,13Z,16R)-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-5-methoxy-9,16-dimethyl-10-[(5S,6R)-6-methyl-5-[methyl(trideuteriomethyl)amino]oxan-2-yl]oxy-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde chemical structure, C43H74N2O14](/s/ACTOXUHEUCPTEW-CFXBGICUSA-N.svg)
Similar structures
Nearest neighbours by Morgan fingerprint Tanimoto similarity
![2-[(4R,6S,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde chemical structure, C35H59NO13](/s/XYJOGTQLTFNMQG-XMWOZFRUSA-N.svg)
![2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyloxan-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde chemical structure, C35H59NO13](/s/XYJOGTQLTFNMQG-GGYHRAIESA-N.svg)
![4-[(3-Carboxy-2-hydroxy-naphthalen-1-yl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid, 2-[(2R,4E,6E,8R,9R,11R,12S,13S,14R)-12-[(2S,3R,4S,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyl-oxan-2-yl]oxy-4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl]oxy-8- chemical structure, C66H90N2O20](/s/BJKLPSFSLQTCGC-SMCAJGNSSA-N.svg)
Frequently asked questions
Quick answers about Spiramycin I, based on the data on this page
What is Spiramycin I?
What is the CAS number of Spiramycin I?
What is the molecular formula and weight of Spiramycin I?
What is Spiramycin I used for?
Is Spiramycin I hazardous?
What is the HS code of Spiramycin I?
Where can I buy Spiramycin I?
What is the price of Spiramycin I?
Guides for buyers
Practical guides that help when you source, ship or handle Spiramycin I
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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