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Antibiotics and anti-infectives

Sulfacetamide

Also known as Sulphacetamide, Acetosulfamine, N-((4-Aminophenyl)sulfonyl)acetamide

CAS 144-80-9Formula C8H10N2O3SMolar mass 214.25 g/molEC 205-640-6
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard 79 suppliers listed Drug substance
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Sulfacetamide chemical structure, C8H10N2O3S, CAS 144-80-9
2D chemical structure

Key facts

What buyers check first

All properties
Physical form
Powder
Melting point
182.2 to 183.9
Solubility
Less than 0.1 mg/mL at 61 °F
HS code
293590
Category
Antibiotics and anti-infectives
Illustrative photo, assorted laboratory chemical bottles and jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Sulfacetamide?

Plain description, key identifiers and synonyms

Sulfacetamide is a sulfonamide that is sulfanilamide acylated on the sulfonamide nitrogen. It has a role as an antimicrobial agent, an antiinfective agent, an antibacterial drug and an EC 2.5.1.15 (dihydropteroate synthase) inhibitor. It is a substituted aniline and a N-sulfonylcarboxamide. It is functionally related to a sulfanilamide. It is a conjugate acid of a sulfacetamide(1-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-(4-aminophenyl)sulfonylacetamide
CAS number
144-80-9 CAS number cross-checkedOther or deprecated CAS: 5414-91-5
EC number
205-640-6
Molecular formula
C8H10N2O3S
UNII
4965G3J0F5
MDL number
MFCD00066501
InChIKey
SKIVFJLNDNKQPD-UHFFFAOYSA-N
InChI
InChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)
SMILES (canonical and isomeric)
CC(=O)NS(=O)(=O)C1=CC=C(C=C1)N

Synonyms

  • Sulphacetamide
  • Acetosulfamine
  • N-((4-Aminophenyl)sulfonyl)acetamide
  • N-Acetylsulfanilamide
  • Urosulfon
  • N-Sulfanilylacetamide
  • Acetosulfamin
  • Acetocid
  • Sulfacet
  • N-(4-aminophenyl)sulfonylacetamide
  • N-Sulphanilylacetamide
  • Formosulfacetamide
  • Sulfacetimide
  • Albamine
  • Sulphasil
  • Urosulfone
  • Alesten
  • Sulamyd
  • Sulfanilacetamide
  • Steramide
  • Region
  • Sulfanilazetamid
  • Bleph-10
  • p-Aminobenzenesulfonacetamide
  • N-Acetyl-4-aminobenzenesulfonamide
Show all 39 synonyms
  • Sulfacetamida
  • Sulfacetamidum
  • Sulphacetamidum
  • p-Aminobenzenesulfonoacetamide
  • N'-Acetylsulfanilamide
  • N-[(4-Aminophenyl)sulfonyl]acetamide
  • Acetamide, N-sulfanilyl-
  • N-((p-Aminophenyl)sulfonyl)acetamide
  • Sulfanilamide, N(sup 1)-acetyl-
  • N(sup 1)-Acetyl-4-aminophenylsulfonamide
  • N-[(p-Aminophenyl)sulfonyl]acetamide
  • N(1)-acetylsulfanilamide
  • Acetamide, N-((4-aminophenyl)sulfonyl)-
  • Acetamide, N-[(4-aminophenyl)sulfonyl]-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Powderexp.
Melting point
182.2 to 183.9exp.
Solubility
Less than 0.1 mg/mL at 61 °Fexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
214.25 g/molcalc.
Exact mass
214.0412 Dacalc.
LogP (octanol/water)
0.09calc.
Topological polar surface area
89.26 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
2calc.
Heavy atoms
14calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.13calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H317May cause an allergic skin reaction.
  • H335May cause respiratory irritation.
  • H341Suspected of causing genetic defects.
Precautionary statements (15)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Sulfacetamide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 79 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

79 suppliers in 14 countries

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Sulfacetamide price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Bacterial Agents
  • Anti-Infective Agents, Local
  • Anti-Infective Agents, Urinary

Roles

  • antibacterial agent
  • antibacterial drug
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • enzyme inhibitor
  • ophthalmology drug
  • pharmaceutical

Pharmacology

Sulfacetamide is a Sulfonamide Antibacterial.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Sulfacetamide is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Sulfacetamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Sulfacetamide, based on the data on this page

What is Sulfacetamide?

Sulfacetamide is a sulfonamide that is sulfanilamide acylated on the sulfonamide nitrogen. It has a role as an antimicrobial agent, an antiinfective agent, an antibacterial drug and an EC 2.5.1.15 (dihydropteroate synthase) inhibitor. It is a substituted aniline and a N-sulfonylcarboxamide.

What is the CAS number of Sulfacetamide?

The CAS registry number of Sulfacetamide is 144-80-9. Other or deprecated CAS numbers: 5414-91-5.

What is the molecular formula and weight of Sulfacetamide?

The molecular formula of Sulfacetamide is C8H10N2O3S and its molar mass is 214.25 g/mol.

What is Sulfacetamide used for?

Use classes: Pharmaceuticals.

Is Sulfacetamide hazardous?

Sulfacetamide carries the GHS signal word "Warning". Main hazards: may cause an allergic skin reaction, may cause respiratory irritation, suspected of causing genetic defects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Sulfacetamide?

Sulfacetamide is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Sulfacetamide?

CompoundList lists 79 suppliers of Sulfacetamide in United States, China, United Kingdom, Germany and 10 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Sulfacetamide in India?

2 suppliers in India list Sulfacetamide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Sulfacetamide?

Suppliers quote Sulfacetamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Sulfacetamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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