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Sumatriptan succinate chemical structure, C18H27N3O6S, CAS 103628-48-4
2D chemical structure

Key facts

What buyers check first

CAS number
103628-48-4
Formula
C18H27N3O6S
Molar mass
413.50 g/mol
EC number
600-463-4
HS code
293590
Category
Pharmaceuticals and APIs

What is Sumatriptan succinate?

Plain description, key identifiers and synonyms

Sumatriptan succinate is a succinate salt obtained by reaction of sumatriptan with one equivalent of succinic acid. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used for the acute treatment of migraine with or without aura in adults. It has a role as a serotonergic agonist and a vasoconstrictor agent. It contains a sumatriptan(1+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
butanedioic acid, 1-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-methylmethanesulfonamide
CAS number
103628-48-4 CAS number cross-checked
EC number
600-463-4
Molecular formula
C18H27N3O6S
UNII
J8BDZ68989
MDL number
MFCD00902856
InChIKey
PORMUFZNYQJOEI-UHFFFAOYSA-N
InChI
InChI=1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)
SMILES (canonical and isomeric)
CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCN(C)C.C(CC(=O)O)C(=O)O

Synonyms

  • Sumavel DosePro
  • Alsuma
  • Onzetra Xsail
  • Imitrex Statdose
  • GR 43175C
  • Zembrace SymTouch
  • Sumatriptan Galpharm
  • Sumatriptan (as succinate)
  • Zecuity
  • Migraitan
  • Imigran subject
  • Migraleve ultra
  • Migraine Pack
  • Imigran 50
  • sumatriptan succinate tablet
  • Sumatriptan Succinate, MENTHOLUM, BELLADONNA, IRIS VERSICOLOR, SANGUINARIA CANADENSIS
  • 1-(3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)-N-methylmethanesulfonamide succinate
  • sumatriptan hydrogen succinate
  • Micralgin
  • Migratan
  • GR 43175
  • Sumatriptan (succinate)
  • 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate
  • Migratriptan
  • Antibet
Show all 37 synonyms
  • Diletan
  • Imijekt
  • Novelian
  • Permicran
  • Sumadol
  • Sumatrin
  • Sumigrene
  • Suminat
  • Migmax
  • Imitrex (TN)
  • 1-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide succinate
  • 1-{3-[2-(dimethylamino)ethyl]-1h-indol-5-yl}-n-methylmethanesulfonamide succinate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
413.50 g/molcalc.
Exact mass
413.1621 Dacalc.
LogP (octanol/water)
1.26calc.
Topological polar surface area
139.8 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
9calc.
Heavy atoms
28calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.44calc.
Formal charge
0calc.
Stereocentres
0calc.
Components
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2[nH]ccc2c1

c1ccc2[nH]ccc2c1

2 rings, 9 atoms, the Indole ring system.

25,097 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H318Causes serious eye damage.
  • H361Suspected of damaging fertility or the unborn child.
  • H412Harmful to aquatic life with long lasting effects.
Precautionary statements (9)
  • P203Obtain, read and follow all safety instructions before use.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Sumatriptan succinate suppliers

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Sumatriptan succinate price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • cardiovascular drug
  • neurotransmitter agent
  • pharmaceutical
  • serotonergic agonist
  • serotonergic drug
  • vasoconstrictor agent

Pharmacology

Sumatriptan Succinate is the succinate salt form of sumatriptan, a member of the triptan class of compounds with anti-migraine property. Sumatriptan succinate selectively binds to and activates serotonin 5-HT1 receptors. This results in constriction of meningeal, dural, cerebral or pial blood vessels via stimulation of the 5-HT1B receptors, thereby reducing the vascular pulsation and may provide relief in migraine headaches.

Read more

Furthermore, agonistic action of this agent through presynaptic stimulation of 5-HT1D and/or 5-HT1F receptors prevents release of vasoactive and pro-inflammatory neuropeptide (calcitonin gene-related peptide), thereby may also relieve migraine headaches. In addition, central inhibition of pain transmission via the inhibition of trigeminal neurons in the brain stems and upper spinal cord mediated by 5-HT1B, 5-HT1D or 5-HT 1F receptors also aides in the alleviation of migraine pain.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Sumatriptan succinate is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Sumatriptan succinate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Sumatriptan succinate, based on the data on this page

What is Sumatriptan succinate?

Sumatriptan succinate is a succinate salt obtained by reaction of sumatriptan with one equivalent of succinic acid. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used for the acute treatment of migraine with or without aura in adults.

What is the CAS number of Sumatriptan succinate?

The CAS registry number of Sumatriptan succinate is 103628-48-4.

What is the molecular formula and weight of Sumatriptan succinate?

The molecular formula of Sumatriptan succinate is C18H27N3O6S and its molar mass is 413.50 g/mol.

What is Sumatriptan succinate used for?

Known uses and roles of Sumatriptan succinate include cardiovascular drug, neurotransmitter agent, pharmaceutical, serotonergic agonist, serotonergic drug and 1 more.

Is Sumatriptan succinate hazardous?

Sumatriptan succinate carries the GHS signal word "Danger". Main hazards: causes serious eye damage, suspected of damaging fertility or the unborn child, harmful to aquatic life with long lasting effects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Sumatriptan succinate?

Sumatriptan succinate is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Sumatriptan succinate?

CompoundList lists 120 suppliers of Sumatriptan succinate in United States, China, India, Spain and 16 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Sumatriptan succinate in India?

23 suppliers in India list Sumatriptan succinate on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Sumatriptan succinate?

Suppliers quote Sumatriptan succinate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Sumatriptan succinate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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