Sumatriptan succinate
Also known as Sumavel DosePro, Alsuma, Onzetra Xsail
Key facts
What buyers check first
- CAS number
- 103628-48-4
- Formula
- C18H27N3O6S
- Molar mass
- 413.50 g/mol
- EC number
- 600-463-4
- HS code
- 293590
- Category
- Pharmaceuticals and APIs
What is Sumatriptan succinate?
Plain description, key identifiers and synonyms
Sumatriptan succinate is a succinate salt obtained by reaction of sumatriptan with one equivalent of succinic acid. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used for the acute treatment of migraine with or without aura in adults. It has a role as a serotonergic agonist and a vasoconstrictor agent. It contains a sumatriptan(1+).
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- butanedioic acid, 1-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-methylmethanesulfonamide
- CAS number
- 103628-48-4 CAS number cross-checked
- EC number
- 600-463-4
- Molecular formula
- C18H27N3O6S
- UNII
- J8BDZ68989
- MDL number
- MFCD00902856
- InChIKey
- PORMUFZNYQJOEI-UHFFFAOYSA-N
- InChI
- InChI=1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)
- SMILES (canonical and isomeric)
- CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCN(C)C.C(CC(=O)O)C(=O)O
Synonyms
- Sumavel DosePro
- Alsuma
- Onzetra Xsail
- Imitrex Statdose
- GR 43175C
- Zembrace SymTouch
- Sumatriptan Galpharm
- Sumatriptan (as succinate)
- Zecuity
- Migraitan
- Imigran subject
- Migraleve ultra
- Migraine Pack
- Imigran 50
- sumatriptan succinate tablet
- Sumatriptan Succinate, MENTHOLUM, BELLADONNA, IRIS VERSICOLOR, SANGUINARIA CANADENSIS
- 1-(3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)-N-methylmethanesulfonamide succinate
- sumatriptan hydrogen succinate
- Micralgin
- Migratan
- GR 43175
- Sumatriptan (succinate)
- 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate
- Migratriptan
- Antibet
Show all 37 synonymsShow fewer synonyms
- Diletan
- Imijekt
- Novelian
- Permicran
- Sumadol
- Sumatrin
- Sumigrene
- Suminat
- Migmax
- Imitrex (TN)
- 1-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide succinate
- 1-{3-[2-(dimethylamino)ethyl]-1h-indol-5-yl}-n-methylmethanesulfonamide succinate
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 413.50 g/molcalc.Computed value |
|---|---|
| Exact mass | 413.1621 Dacalc.Computed value |
| LogP (octanol/water) | 1.26calc.Computed value |
| Topological polar surface area | 139.8 Ųcalc.Computed value |
| Hydrogen bond donors | 4calc.Computed value |
| Hydrogen bond acceptors | 5calc.Computed value |
| Rotatable bonds | 9calc.Computed value |
| Heavy atoms | 28calc.Computed value |
| Rings | 2calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0.44calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Components | 2calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H318Causes serious eye damage.
- H361Suspected of damaging fertility or the unborn child.
- H412Harmful to aquatic life with long lasting effects.
Precautionary statements (9)
- P203Obtain, read and follow all safety instructions before use.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P273Avoid release to the environment.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P317Get medical help.
- P318If exposed or concerned, get medical advice.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidSumatriptan succinate suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China, Changsha ManufacturerUnclaimed profileSumatriptan SuccinateGrade, purity and minimum order on requestPrice on request
- Spain, Rubi ManufacturerUnclaimed profileSumatriptan SuccinateGrade, purity and minimum order on requestPrice on request
- Iran, Tehran ManufacturerUnclaimed profileSumatriptan SuccinateGrade, purity and minimum order on requestPrice on request
- India, HyderabadUnclaimed profileSumatriptan SuccinateGrade, purity and minimum order on requestPrice on request
- China ManufacturerUnclaimed profileSumatriptan SuccinateGrade, purity and minimum order on requestPrice on request
- China, Changsha ManufacturerUnclaimed profileSumatriptan SuccinateGrade, purity and minimum order on requestPrice on request
- China, TianjinUnclaimed profileSumatriptan SuccinateGrade, purity and minimum order on requestPrice on request
- India, Valsad ManufacturerUnclaimed profileSumatriptan SuccinateGrade, purity and minimum order on requestPrice on request
- China, Changsha ManufacturerUnclaimed profileSumatriptan SuccinateGrade, purity and minimum order on requestPrice on request
- Pakistan ManufacturerUnclaimed profileSumatriptan SuccinateGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
120 suppliers in 20 countries
- United States33
- China28
- India23
- Spain6
- United Kingdom5
- Germany4
- and 14 more countries
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Sumatriptan succinate price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Roles
- cardiovascular drug
- neurotransmitter agent
- pharmaceutical
- serotonergic agonist
- serotonergic drug
- vasoconstrictor agent
Pharmacology
Sumatriptan Succinate is the succinate salt form of sumatriptan, a member of the triptan class of compounds with anti-migraine property. Sumatriptan succinate selectively binds to and activates serotonin 5-HT1 receptors. This results in constriction of meningeal, dural, cerebral or pial blood vessels via stimulation of the 5-HT1B receptors, thereby reducing the vascular pulsation and may provide relief in migraine headaches.
Read more
Furthermore, agonistic action of this agent through presynaptic stimulation of 5-HT1D and/or 5-HT1F receptors prevents release of vasoactive and pro-inflammatory neuropeptide (calcitonin gene-related peptide), thereby may also relieve migraine headaches. In addition, central inhibition of pain transmission via the inhibition of trigeminal neurons in the brain stems and upper spinal cord mediated by 5-HT1B, 5-HT1D or 5-HT 1F receptors also aides in the alleviation of migraine pain.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Sumatriptan succinate is traded under.
Sulphonamides, other
- United States23.6%
- Slovenia19.1%
- Spain11.7%
* Partner reported figures, a lower bound.
The HS code shown for Sumatriptan succinate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Sumatriptan succinate, based on the data on this page
What is Sumatriptan succinate?
What is the CAS number of Sumatriptan succinate?
What is the molecular formula and weight of Sumatriptan succinate?
What is Sumatriptan succinate used for?
Is Sumatriptan succinate hazardous?
What is the HS code of Sumatriptan succinate?
Where can I buy Sumatriptan succinate?
Where can I buy Sumatriptan succinate in India?
What is the price of Sumatriptan succinate?
Guides for buyers
Practical guides that help when you source, ship or handle Sumatriptan succinate
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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