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Boronic acids and esters

Talabostat

Also known as Val-boroPro, valinyl-boroproline, [(2R)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidin-2-yl]boronic acid

CAS 149682-77-9Formula C9H19BN2O3Molar mass 214.07 g/mol
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Talabostat chemical structure, C9H19BN2O3, CAS 149682-77-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
149682-77-9
Formula
C9H19BN2O3
Molar mass
214.07 g/mol
HS code
293399
Category
Boronic acids and esters

What is Talabostat?

Plain description, key identifiers and synonyms

Talabostat is a small molecule with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[(2R)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidin-2-yl]boronic acid
CAS number
149682-77-9 CAS number cross-checkedOther or deprecated CAS: 150080-09-4
Molecular formula
C9H19BN2O3
UNII
KZ1O2SH88Z
InChIKey
FKCMADOPPWWGNZ-YUMQZZPRSA-N
InChI
InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8-/m0/s1
Canonical SMILES
CC(C)C(N)C(=O)N1CCCC1B(O)O
Isomeric SMILES
B([C@@H]1CCCN1C(=O)[C@H](C(C)C)N)(O)O

Synonyms

  • Val-boroPro
  • valinyl-boroproline
  • [(2R)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidin-2-yl]boronic acid
  • PT100 cpd
  • ((2R)-1-((2S)-2-amino-3-methylbutanoyl)pyrrolidin-2-yl)boronic acid
  • talabostatum
  • BXCL701
  • BXCL 701
  • BXCL-701
  • Val-boro-pro
  • L-valinyl-L-boroproline
  • ((R)-1-(L-Valyl)pyrrolidin-2-yl)boronic acid
  • Pyrrolidine derivative
  • ((R)-1-((S)-2-Amino-3-methylbutanoyl)pyrrolidin-2-yl)boronic acid
  • Val-boroPro, PT100
  • Valinyl-L-Boroproline
  • PT 100
  • ValboroPro
  • Ketopyrrolidine derivative
  • Talabostat (USAN/INN)
  • compound 1
  • [(2R)-1-L-Valylpyrrolidin-2-yl]boronic acid
  • ((R)-1-((S)-2-Amino-3-methylbutanoyl)pyrrolidin-2-yl)boronicacid
  • (R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-ylboronic acid
  • (S)-2-Amino-3-methyl-2-boronic acid-1-pyrrolidin-1-yl-butan-1-one
Show all 29 synonyms
  • (S)-2-Amino-1-((R)-2-dihydroxyboron-pyrrolidin-1-yl)-3-methyl-butan-1-one
  • Boronic acid, ((2R)-1-((2S)-2-amino-3-methyl-1-oxobutyl)-2-pyrrolidinyl)
  • Boronic acid, ((2R)-1-((2S)-2-amino-3-methyl-1-oxobutyl)-2-pyrrolidinyl)-
  • Boronic acid, (1-(2-amino-3-methyl-1-oxobutyl)-2-pyrrolidinyl)-, (R-(R*,S*))-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
214.07 g/molcalc.
Exact mass
214.1489 Dacalc.
LogP (octanol/water)
-1.03calc.
Topological polar surface area
86.79 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
3calc.
Heavy atoms
15calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.89calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCNC1

C1CCNC1

1 ring, 5 atoms, the Pyrrolidine ring system.

22,348 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Talabostat suppliers

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Talabostat price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antineoplastic agent
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Talabostat is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Talabostat is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Talabostat, based on the data on this page

What is Talabostat?

Talabostat is a small molecule with antineoplastic and hematopoiesis- stimulating activities.

What is the CAS number of Talabostat?

The CAS registry number of Talabostat is 149682-77-9. Other or deprecated CAS numbers: 150080-09-4.

What is the molecular formula and weight of Talabostat?

The molecular formula of Talabostat is C9H19BN2O3 and its molar mass is 214.07 g/mol.

What is Talabostat used for?

Known uses and roles of Talabostat include building blocks in research and laboratory, screening compounds in research and laboratory, antineoplastic agent and pharmaceutical.

Is Talabostat hazardous?

No GHS hazard classification for Talabostat is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Talabostat?

Talabostat is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Talabostat?

Post a free request on CompoundList and suppliers of Talabostat will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Talabostat?

Suppliers quote Talabostat on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Talabostat

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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