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Thymogen

Also known as Oglufanide, Glutamyltryptophan, alpha-Glu-Trp

CAS 38101-59-6Formula C16H19N3O5Molar mass 333.34 g/mol
Thymogen chemical structure, C16H19N3O5, CAS 38101-59-6
2D chemical structure

Key facts

What buyers check first

CAS number
38101-59-6
Formula
C16H19N3O5
Molar mass
333.34 g/mol
HS code
293399
Category
Peptides

What is Thymogen?

Plain description, key identifiers and synonyms

Glu-Trp is a dipeptide composed of L-glutamic acid and L-tryptophan joined by a peptide linkage. It has a role as a metabolite, an antineoplastic agent, an immunomodulator and an angiogenesis modulating agent. It is functionally related to a L-glutamic acid and a L-tryptophan.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(4S)-4-amino-5-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxopentanoic acid
CAS number
38101-59-6Other or deprecated CAS: 122933-59-9
Molecular formula
C16H19N3O5
UNII
4RHY598T5U
MDL number
MFCD00037953
InChIKey
LLEUXCDZPQOJMY-AAEUAGOBSA-N
InChI
InChI=1S/C16H19N3O5/c17-11(5-6-14(20)21)15(22)19-13(16(23)24)7-9-8-18-12-4-2-1-3-10(9)12/h1-4,8,11,13,18H,5-7,17H2,(H,19,22)(H,20,21)(H,23,24)/t11-,13-/m0/s1
Canonical SMILES
NC(CCC(=O)O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O
Isomeric SMILES
C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)NC(=O)[C@H](CCC(=O)O)N

Synonyms

  • Oglufanide
  • Glutamyltryptophan
  • alpha-Glu-Trp
  • L-Tryptophan, L-alpha-glutamyl-
  • L-alpha-Glu-L-Trp
  • oglufanida
  • oglufanidum
  • H-Glu-Trp-OH
  • Glu-trp
  • L-glutamyl-L-tryptophan
  • Timogen
  • Glutamyl tryptophan
  • L-alpha-Glutamyl-L-tryptophan
  • L-Glu-L-Trp
  • Thymogen(Oglufanide)
  • (S)-4-Amino-5-(((S)-1-carboxy-2-(1H-indol-3-yl)ethyl)amino)-5-oxopentanoic acid
  • L-Tryptophan, N-L-alpha-glutamyl-
  • (4S)-4-amino-5-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxopentanoic acid
  • (4S)-4-Amino-5-{[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino}-5-oxopentanoic acid
  • IM 862 dipeptide
  • Oglufanide dis
  • EW dipeptide
  • E-W Dipeptide
  • glutamyl-tryptophan
  • Thymogen(Oglufanide)?
Show all 34 synonyms
  • N-L-a-glutamyl-L-tryptophan
  • Glutamate Tryptophan dipeptide
  • Glutamate-Tryptophan dipeptide
  • L-Tryptophan, L-|A-glutamyl-
  • 4-Amino-5-[[1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxopentanoic acid
  • (4S)-4-[N-((1S)-1-carboxy-2-indol-3-ylethyl)carbamoyl]-4-aminobutanoic acid
  • (4S)-4-amino-5-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxo-pentanoic acid
  • (S)-4-amino-5-((S)-1-carboxy-2-(1H-indol-3-yl)ethylamino)-5-oxopentanoic acid
  • (S)-4-Amino-5-[[(S)-1-carboxy-2-(3-indolyl)ethyl]amino]-5-oxopentanoic Acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
333.34 g/molcalc.
Exact mass
333.1325 Dacalc.
LogP (octanol/water)
0.47calc.
Topological polar surface area
145.5 Ųcalc.
Hydrogen bond donors
5calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
8calc.
Heavy atoms
24calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.31calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2[nH]ccc2c1

c1ccc2[nH]ccc2c1

2 rings, 9 atoms, the Indole ring system.

25,097 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Thymogen suppliers

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  • United States, DavieUnclaimed profile
    ThymogenGrade, purity and minimum order on request
    Price on request
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Where suppliers are based

1 supplier in 1 country

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Thymogen price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Adjuvants, Immunologic
  • Angiogenesis Inhibitors
  • Anti-Arrhythmia Agents
  • Antidotes

Roles

  • angiogenesis modulating agent
  • antineoplastic agent
  • immunomodulator
  • metabolite
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Thymogen is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Thymogen is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Thymogen, based on the data on this page

What is Thymogen?

Glu-Trp is a dipeptide composed of L-glutamic acid and L-tryptophan joined by a peptide linkage. It has a role as a metabolite, an antineoplastic agent, an immunomodulator and an angiogenesis modulating agent. It is functionally related to a L-glutamic acid and a L-tryptophan.

What is the CAS number of Thymogen?

The CAS registry number of Thymogen is 38101-59-6. Other or deprecated CAS numbers: 122933-59-9.

What is the molecular formula and weight of Thymogen?

The molecular formula of Thymogen is C16H19N3O5 and its molar mass is 333.34 g/mol.

What is Thymogen used for?

Known uses and roles of Thymogen include angiogenesis modulating agent, antineoplastic agent, immunomodulator, metabolite, pharmaceutical and 4 more.

Is Thymogen hazardous?

No GHS hazard classification for Thymogen is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Thymogen?

Thymogen is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Thymogen?

CompoundList lists 1 supplier of Thymogen in United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Thymogen?

Suppliers quote Thymogen on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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