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Antibiotics and anti-infectives

Tioconazole

Also known as Vagistat, Vagistat-1, Trosyd

CAS 65899-73-2Formula C16H13Cl3N2OSMolar mass 387.72 g/molEC 265-973-8
GHS signal word: Warning. Pictograms: Harmful or irritant, Serious health hazard, Hazardous to the environment 51 suppliers listed Drug substance
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Tioconazole chemical structure, C16H13Cl3N2OS, CAS 65899-73-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
65899-73-2
Formula
C16H13Cl3N2OS
Molar mass
387.72 g/mol
EC number
265-973-8
HS code
293499
Category
Antibiotics and anti-infectives

What is Tioconazole?

Plain description, key identifiers and synonyms

1-{2-[(2-chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl}imidazole is a member of the class of imidazoles that comprises 2-(2,4-dichlorophenyl)ethylimidazole carrying an additional (2-chloro-3-thienyl)methoxy substituent at position 2. It is a dichlorobenzene, a member of imidazoles, an ether and a member of thiophenes.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-[2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole
CAS number
65899-73-2 CAS number cross-checked
EC number
265-973-8
Molecular formula
C16H13Cl3N2OS
UNII
S57Y5X1117
MDL number
MFCD00057276
INCI name
TIOCONAZOLE
InChIKey
QXHHHPZILQDDPS-UHFFFAOYSA-N
InChI
InChI=1S/C16H13Cl3N2OS/c17-12-1-2-13(14(18)7-12)15(8-21-5-4-20-10-21)22-9-11-3-6-23-16(11)19/h1-7,10,15H,8-9H2
SMILES (canonical and isomeric)
C1=CC(=C(C=C1Cl)Cl)C(CN2C=CN=C2)OCC3=C(SC=C3)Cl

Synonyms

  • Vagistat
  • Vagistat-1
  • Trosyd
  • Trosyl
  • Tioconazol
  • Tioconazolum
  • 1-(2-((2-chlorothiophen-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
  • (+-)-Tioconazole
  • UK 20349
  • UK-20,349
  • (+-)-1-(2,4-Dichloro-beta-((2-chloro-3-ethenyl)oxy)phenethyl)imidazole
  • 1H-Imidazole, 1-(2-((2-chloro-3-thienyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-
  • 1-{2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
  • trosid
  • tioconazolo
  • Trosderm
  • Tioconazole 1
  • Leader Ticonazole
  • 1H-Imidazole, 1-[2-[(2-chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-
  • Tioconazole 1 Day
  • Leader Tioconazole 1
  • basic care tioconazole
  • Sunmark Tioconazole 1
  • Topcare Tioconazole 1
  • CareOne Tioconazole 1
Show all 38 synonyms
  • Equaline Tioconazole 1
  • dg health tioconazole 1
  • good sense tioconazole 1
  • Equate Tioconazole 1 Day
  • Up and Up Tioconazole 1
  • Tioconazole Ointment 6.5%
  • foster and thrive tioconazole
  • Signature Care Tioconazole 1
  • Monistat tioconazole 1
  • Tioconazole 1 1 Dose Treatment
  • Gyno-trosyd
  • Fungibacid
  • Zoniden

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
387.72 g/molcalc.
Exact mass
385.9814 Dacalc.
LogP (octanol/water)
5.86calc.
Topological polar surface area
27.05 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
6calc.
Heavy atoms
23calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.19calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(C(Cn2ccnc2)OCc2ccsc2)cc1

c1ccc(C(Cn2ccnc2)OCc2ccsc2)cc1

3 rings, 20 atoms.

9 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H302Harmful if swallowed.
  • H317May cause an allergic skin reaction.
  • H361Suspected of damaging fertility or the unborn child.
  • H361dSuspected of damaging the unborn child.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (17)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Tioconazole suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 51 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

51 suppliers in 13 countries

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Tioconazole price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name TIOCONAZOLE(antimicrobial)

Pharmacological actions

  • 14-alpha Demethylase Inhibitors
  • Antifungal Agents

Roles

  • antifungal agent
  • antiinfective agent
  • antimicrobial agent
  • enzyme inhibitor
  • pharmaceutical
  • sterol biosynthesis inhibitor
  • sterol demethylation inhibitor

Cosmetic functions

  • Antimicrobial

Pharmacology

Tioconazole is an Azole Antifungal.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Tioconazole is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Tioconazole is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Tioconazole, based on the data on this page

What is Tioconazole?

1-{2-[(2-chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl}imidazole is a member of the class of imidazoles that comprises 2-(2,4-dichlorophenyl)ethylimidazole carrying an additional (2-chloro-3-thienyl)methoxy substituent at position 2.

What is the CAS number of Tioconazole?

The CAS registry number of Tioconazole is 65899-73-2.

What is the molecular formula and weight of Tioconazole?

The molecular formula of Tioconazole is C16H13Cl3N2OS and its molar mass is 387.72 g/mol.

What is Tioconazole used for?

Known uses and roles of Tioconazole include antifungals in pharmaceuticals, preservatives in cosmetics and personal care, antifungal agent, antiinfective agent, antimicrobial agent and 7 more.

Is Tioconazole hazardous?

Tioconazole carries the GHS signal word "Warning". Main hazards: harmful if swallowed, may cause an allergic skin reaction, suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Tioconazole?

Tioconazole is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Tioconazole?

CompoundList lists 51 suppliers of Tioconazole in China, United States, India, United Arab Emirates and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Tioconazole in India?

6 suppliers in India list Tioconazole on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Tioconazole?

Suppliers quote Tioconazole on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Tioconazole

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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