Torasemide
Also known as Torsemide, Luprac, Torasemida
Key facts
What buyers check first
- CAS number
- 56211-40-6
- Formula
- C16H20N4O3S
- Molar mass
- 348.43 g/mol
- EC number
- 637-197-3
- HS code
- 293590
- Category
- Cardiovascular and metabolic drugs
What is Torasemide?
Plain description, key identifiers and synonyms
Torasemide is an N-sulfonylurea obtained by formal condensation of [(3-methylphenyl)amino]pyridine-3-sulfonic acid with the free amino group of N-isopropylurea. It is a potent loop diuretic used for the treatment of hypertension and edema in patients with congestive heart failure. It has a role as an antihypertensive agent and a loop diuretic. It is an aminopyridine, a secondary amino compound and a N-sulfonylurea. It is functionally related to a 4-aminopyridine.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 1-[[4-(3-methylanilino)-3-pyridinyl]sulfonyl]-3-propan-2-ylurea
- CAS number
- 56211-40-6 CAS number cross-checked
- EC number
- 637-197-3
- Molecular formula
- C16H20N4O3S
- UNII
- W31X2H97FB
- MDL number
- MFCD00866166
- InChIKey
- NGBFQHCMQULJNZ-UHFFFAOYSA-N
- InChI
- InChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)
- SMILES (canonical and isomeric)
- CC1=CC(=CC=C1)NC2=C(C=NC=C2)S(=O)(=O)NC(=O)NC(C)C
Synonyms
- Torsemide
- Luprac
- Torasemida
- Torasemidum
- Soaanz
- Upcard
- JDL 464
- AC 4464
- Torasemide anhydrous
- 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea
- BM 02015
- N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide
- 3-Pyridinesulfonamide, N-(((1-methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-
- 3-Pyridinesulfonamide, N-[[(1-methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-
- 1-{4-[(3-methylphenyl)amino]pyridine-3-sulfonyl}-3-(propan-2-yl)urea
- n-[[(1-methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide
- 1-(4-((3-methylphenyl)amino)pyridine-3-sulfonyl)-3-(propan-2-yl)urea
- N-((4-((3-methylphenyl)imino)-1,4-dihydropyridin-3-yl)sulfonyl)propane-2-carbamimidic acid
- N-({4-[(3-methylphenyl)imino]-1,4-dihydropyridin-3-yl}sulfonyl)propane-2-carbamimidic acid
- 1-isopropyl-3-((4-(3-methylphenylamino)pyridine)-3-sulfonyl)urea
- Torem 5
- UpCArd-CA1
- Torem 10
- Torem 2.5
- UpCArd-CA1 TORSEMIDE
Show all 34 synonymsShow fewer synonyms
- Demadex
- N-(Isopropylcarbamoyl)-4-(m-tolylamino)pyridine-3-sulfonamide
- Unat
- 1-[4-(3-methylanilino)pyridin-3-yl]sulfonyl-3-propan-2-ylurea
- Torasemide, Anhydrous
- Toradiur
- N-[(isopropylamino)carbonyl]-4-[(3-methylphenyl)amino]pyridine-3-sulfonamide
- Dilutol
- Torocard
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 348.43 g/molcalc.Computed value |
|---|---|
| Exact mass | 348.1256 Dacalc.Computed value |
| LogP (octanol/water) | 2.53calc.Computed value |
| Topological polar surface area | 100.2 Ųcalc.Computed value |
| Hydrogen bond donors | 3calc.Computed value |
| Hydrogen bond acceptors | 5calc.Computed value |
| Rotatable bonds | 5calc.Computed value |
| Heavy atoms | 24calc.Computed value |
| Rings | 2calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0.25calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
c1ccc(Nc2ccncc2)cc1
2 rings, 13 atoms, the N-Phenylpyridin-4-amine ring system.
380 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H319Causes serious eye irritation.
- H361Suspected of damaging fertility or the unborn child.
Precautionary statements (8)
- P203Obtain, read and follow all safety instructions before use.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P318If exposed or concerned, get medical advice.
- P337 + P317If eye irritation persists: Get medical help.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidTorasemide suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- China, Jingdezhen ManufacturerUnclaimed profileTorasemideGrade, purity and minimum order on requestPrice on request
- India, AnkleshwarUnclaimed profileTorsemideGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileTorasemideGrade, purity and minimum order on requestPrice on request
- India, AnkleshwarUnclaimed profileTorsemideGrade, purity and minimum order on requestPrice on request
- India, MumbaiUnclaimed profileTorasemideGrade, purity and minimum order on requestPrice on request
- China, Hangzhou ManufacturerUnclaimed profileTorasemideGrade, purity and minimum order on requestPrice on request
- India, Bhayli, Vadodara ManufacturerUnclaimed profileTorsemideGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileTorasemideGrade, purity and minimum order on requestPrice on request
- ChinaUnclaimed profileTorasemide(anhydrous)Grade, purity and minimum order on requestPrice on request
- India, MumbaiUnclaimed profileTorasemideGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
135 suppliers in 20 countries
- India33
- United States33
- China32
- Germany6
- United Kingdom5
- Hong Kong3
- and 14 more countries
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Torasemide price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Use classes: Pharmaceuticals, Animal Drugs.
Industries and functions
Pharmacological actions
- Antihypertensive Agents
- Diuretics
- Sodium Potassium Chloride Symporter Inhibitors
Roles
- antihypertensive agent
- cardiovascular drug
- diuretic
- hypoglycemic agent
- loop diuretic
- pharmaceutical
Pharmacology
Torsemide is a Loop Diuretic. The physiologic effect of torsemide is by means of Increased Diuresis at Loop of Henle.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Torasemide is traded under.
Sulphonamides, other
- United States23.6%
- Slovenia19.1%
- Spain11.7%
* Partner reported figures, a lower bound.
The HS code shown for Torasemide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Torasemide, based on the data on this page
What is Torasemide?
What is the CAS number of Torasemide?
What is the molecular formula and weight of Torasemide?
What is Torasemide used for?
Is Torasemide hazardous?
What is the HS code of Torasemide?
Where can I buy Torasemide?
Where can I buy Torasemide in India?
What is the price of Torasemide?
Guides for buyers
Practical guides that help when you source, ship or handle Torasemide
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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