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Humectants

Trehalose

Also known as D-(+)-Trehalose, Mycose, alpha,alpha-trehalose

CAS 99-20-7Formula C12H22O11Molar mass 342.30 g/molEC 202-739-6
78 suppliers listed Drug substance
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Trehalose chemical structure, C12H22O11, CAS 99-20-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
99-20-7
Formula
C12H22O11
Molar mass
342.30 g/mol
EC number
202-739-6
HS code
294000
Category
Humectants

What is Trehalose?

Plain description, key identifiers and synonyms

Alpha,alpha-trehalose is a trehalose in which both glucose residues have alpha-configuration at the anomeric carbon. It has a role as a geroprotector, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite.

Trehalose is a chemical compound from plants, fungi, bacteria.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol
CAS number
99-20-7 CAS number cross-checked
EC number
202-739-6
Molecular formula
C12H22O11
UNII
B8WCK70T7I
MDL number
MFCD00006628
INCI name
TREHALOSE
InChIKey
HDTRYLNUVZCQOY-LIZSDCNHSA-N
InChI
InChI=1S/C12H22O11/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12/h3-20H,1-2H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-/m1/s1
Canonical SMILES
OCC1OC(OC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O
Isomeric SMILES
C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O)O)O)O

Synonyms

  • D-(+)-Trehalose
  • Mycose
  • alpha,alpha-trehalose
  • Ergot sugar
  • alpha-D-Trehalose
  • Cabaletta
  • Mushroom sugar
  • Natural trehalose
  • alpha-D-glucopyranosyl-alpha-D-glucopyranoside
  • alpha,alpha'-Trehalose
  • alpha-D-glucopyranosyl alpha-D-glucopyranoside
  • (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol
  • (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxane-3,4,5-triol
  • (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy)oxane-3,4,5-triol
  • (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxyoxane-3,4,5-triol
  • GlyTouCan:G92130SN
  • zozu abundant charming hips cream
  • zozu plump beautiful breast cream
  • D-Trehalose
  • D-(+)-Trehalose Anhydrous
  • D-(+)-Trehalose, anhydrous
  • Thealoz
  • alpha-Trehalose
  • Treha
  • Trehaose
Show all 36 synonyms
  • alpha-D-Glucopyranoside, alpha-D-glucopyranosyl
  • alpha,alpha'-D-Trehalose
  • (2R,2'R,3S,3'S,4S,4'S,5R,5'R,6R,6'R)-6,6'-oxybis(2-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol)
  • Trehalose, alpha,alpha'-
  • D-Trehalose, Carrier Protein
  • Trehalose P
  • D(+)Trehalose
  • Trehalose (8CI)
  • alpha-alpha-Trehalose
  • D-trehalose-anhydrous
  • D-Trehalose anhydrous

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
342.30 g/molcalc.
Exact mass
342.1162 Dacalc.
LogP (octanol/water)
-5.4calc.
Topological polar surface area
189.5 Ųcalc.
Hydrogen bond donors
8calc.
Hydrogen bond acceptors
11calc.
Rotatable bonds
4calc.
Heavy atoms
23calc.
Rings
2calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
10calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCC(OC2CCCCO2)OC1

C1CCC(OC2CCCCO2)OC1

2 rings, 13 atoms, the Tetrahydropyranyl ether ring system.

75 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Trehalose suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 78 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

78 suppliers in 12 countries

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Trehalose price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Use classes: Cosmetics.

Cosmetic ingredient, INCI name TREHALOSE(humectant, moisturising)

Roles

  • Escherichia coli metabolite
  • Saccharomyces cerevisiae metabolite
  • animal metabolite
  • bacterial metabolite
  • eukaryotic metabolite
  • fungal metabolite
  • geroprotector
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite
  • pharmaceutical
  • prokaryotic metabolite
  • protective agent

Functional uses

  • Flavouring and nutrient
  • Humectant
  • Softener and conditioner

Cosmetic functions

  • Humectant
  • Moisturising

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Trehalose is traded under.

HS 2940.00Indicative HS code

Sugar ethers, sugar acetals and sugar esters, and their salts, other than the products of heading 29.37…

World exports in 2024
$1.4B
−5.4% vs 2023, imports $1.42B
2019 to 2024
Top exporters
  1. Germany23.7%
  2. China20.6%
  3. United States11.5%
Top importers
  1. United States14.0%
  2. Japan7.4%
  3. Germany6.1%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Trehalose is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Trehalose, based on the data on this page

What is Trehalose?

Alpha,alpha-trehalose is a trehalose in which both glucose residues have alpha-configuration at the anomeric carbon. It has a role as a geroprotector, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite.

What is the CAS number of Trehalose?

The CAS registry number of Trehalose is 99-20-7.

What is the molecular formula and weight of Trehalose?

The molecular formula of Trehalose is C12H22O11 and its molar mass is 342.30 g/mol.

What is Trehalose used for?

Use classes: Cosmetics.

Is Trehalose hazardous?

No GHS hazard classification for Trehalose is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Trehalose?

Trehalose is usually classified under HS code 294000 (Sugars, chemically pure, other than sucrose, lactose, maltose, glucose and fructose…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Trehalose?

CompoundList lists 78 suppliers of Trehalose in United States, China, Germany, United Kingdom and 8 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Trehalose in India?

2 suppliers in India list Trehalose on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Trehalose?

Suppliers quote Trehalose on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Trehalose

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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