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Sweeteners

(+)-Lactose

Also known as beta-D-Gal-(1->4)-D-Glc, beta-D-Galp-(1->4)-D-Glcp, 1-beta-D-Galactopyranosyl-4-D-glucopyranose

CAS 63-42-3Formula C12H22O11Molar mass 342.30 g/molEC 200-559-2
43 suppliers listed Drug substance
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(+)-Lactose chemical structure, C12H22O11, CAS 63-42-3
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
White, hard, crystalline mass of white powder
Melting point
203.5 °C
Density
1.525
Solubility
In water, 1.95 × 10⁺⁶ mg/L at 20 °C
HS code
294000
Category
Sweeteners
Illustrative photo, off-white crystalline powder in fibre drums in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is (+)-Lactose?

Plain description, key identifiers and synonyms

Lactose is a glycosylglucose disaccharide, found most notably in milk, that consists of D-galactose and D-glucose fragments bonded through a beta-14 glycosidic linkage. The glucose fragment can be in either the alpha- or beta-pyranose form, whereas the galactose fragment can only have the beta-pyranose form. It has a role as a human metabolite.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
CAS number
63-42-3 CAS number cross-checkedOther or deprecated CAS: 64044-51-5
EC number
200-559-2
Molecular formula
C12H22O11
INCI name
LACTOSE
InChIKey
GUBGYTABKSRVRQ-QKKXKWKRSA-N
InChI
InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11?,12+/m1/s1
Canonical SMILES
OCC1OC(OC2C(CO)OC(O)C(O)C2O)C(O)C(O)C1O
Isomeric SMILES
C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](OC([C@@H]([C@H]2O)O)O)CO)O)O)O)O

Synonyms

  • beta-D-Gal-(1->4)-D-Glc
  • beta-D-Galp-(1->4)-D-Glcp
  • 1-beta-D-Galactopyranosyl-4-D-glucopyranose
  • beta-D-galactopyranosyl-(1->4)-D-glucopyranose
  • Lactin
  • Anhydrous lactose
  • Lactose anhydrous
  • Aletobiose
  • Galactinum
  • Tablettose
  • Saccharum lactin
  • Fast-flo
  • Zeparox EP
  • Fast-flo Lactose
  • Lactose Fast-flo
  • Pharmatose 21
  • Pharmatose 450M
  • Lactin (carbohydrate)
  • Lactosum, anhydrous
  • GlyTouCan:G74621DY
  • D-Glucose, 4-O-beta-D-galactopyranosyl-
  • Lactopress anhydrous
  • Lactose,anhydrous
  • Supertab 21an
  • Supertab 22an
Show all 38 synonyms
  • Supertab 24an
  • Laktose
  • Lactobiose
  • Laktobiose
  • Milchzucker
  • beta-Gal1,4-Glc
  • (Gal)1 (Glc)1
  • 4-O-beta-D-galactopyranosyl-D-glucopyranose
  • d-(+)-lactose monohydrate
  • Galbeta1-4Glc
  • Galbeta1-4-Glc
  • Gal(b1-4)Glc
  • Anhydrous lactose (JP18)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White, hard, crystalline mass of white powderexp.
Odour
Odorlessexp.
Taste
Sweetexp.
Melting point
203.5 °Cexp.
Density
1.525exp.
Solubility
In water, 1.95 × 10⁺⁶ mg/L at 20 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
342.30 g/molcalc.
Exact mass
342.1162 Dacalc.
LogP (octanol/water)
-5.4calc.
Topological polar surface area
189.5 Ųcalc.
Hydrogen bond donors
8calc.
Hydrogen bond acceptors
11calc.
Rotatable bonds
4calc.
Heavy atoms
23calc.
Rings
2calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
10calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCC(OC2CCCOC2)OC1

C1CCC(OC2CCCOC2)OC1

2 rings, 13 atoms.

536 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS classification
Hazard pictograms

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

(+)-Lactose suppliers

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All 43 suppliers
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Where suppliers are based

43 suppliers in 13 countries

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(+)-Lactose price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Both forms of lactose are employed, with the alpha-form predominating: as a nutrient in preparing modified milk and food for infants and convalescents ... in baking mixtures. Pharmaceutic aid (tablet and capsule excipient and diluent). To produce lactic acid fermentation in ensilage and food products. As a chromatographic adsorbent in analytical chemistry.

Lactose is included in digestive aid drug products.

Lactose is included in weight control drug products.

Bacteriology ... in confectionery, margarine and butter manufacture, manufacture of penicillin, yeast, edible protein, and riboflavin, culture media.

Use classes: Cosmetics.

Cosmetic ingredient, INCI name LACTOSE(humectant, skin conditioning)

Pharmacological actions

  • Sweetening Agents

Roles

  • animal metabolite
  • eukaryotic metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite

Cosmetic functions

  • Humectant
  • Skin conditioning

How it is made

The liquid whey (about 6.5% dry matter content) is clarified and concentrated in falling film evaporators to 55 - 65% total solids. Upon cooling, the greater part of the lactose crystallizes as lactose monohydrate. The crystal slurry is transferred to a line of decanters and centrifuges and washed several times. ... After drying, milling and fractionation, yellowish lactose (edible grade) of different particle sizes is obtained. After the washing stage the raw product can be redissolved, treated with activated carbon and recrystallized to refined or pharmaceutical grades of lactose. From 1000 kg liquid whey 32.5 kg lactose and 32.5 kg delactosed whey powder are obtained.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code (+)-Lactose is traded under.

HS 2940.00Indicative HS code

Sugar ethers, sugar acetals and sugar esters, and their salts, other than the products of heading 29.37…

World exports in 2024
$1.4B
−5.4% vs 2023, imports $1.42B
2019 to 2024
Top exporters
  1. Germany23.7%
  2. China20.6%
  3. United States11.5%
Top importers
  1. United States14.0%
  2. Japan7.4%
  3. Germany6.1%
Reported customs values in USD, not prices.Full trade data

The HS code shown for (+)-Lactose is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about (+)-Lactose, based on the data on this page

What is (+)-Lactose?

Lactose is a glycosylglucose disaccharide, found most notably in milk, that consists of D-galactose and D-glucose fragments bonded through a beta-14 glycosidic linkage. The glucose fragment can be in either the alpha- or beta-pyranose form, whereas the galactose fragment can only have the beta-pyranose form.

What is the CAS number of (+)-Lactose?

The CAS registry number of (+)-Lactose is 63-42-3. Other or deprecated CAS numbers: 64044-51-5.

What is the molecular formula and weight of (+)-Lactose?

The molecular formula of (+)-Lactose is C12H22O11 and its molar mass is 342.30 g/mol.

What is (+)-Lactose used for?

Both forms of lactose are employed, with the alpha-form predominating: as a nutrient in preparing modified milk and food for infants and convalescents ... in baking mixtures. Pharmaceutic aid (tablet and capsule excipient and diluent). To produce lactic acid fermentation in ensilage and food products.

Is (+)-Lactose hazardous?

No GHS hazard classification for (+)-Lactose is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of (+)-Lactose?

(+)-Lactose is usually classified under HS code 294000 (Sugars, chemically pure, other than sucrose, lactose, maltose, glucose and fructose…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy (+)-Lactose?

CompoundList lists 43 suppliers of (+)-Lactose in China, United States, India, Germany and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy (+)-Lactose in India?

6 suppliers in India list (+)-Lactose on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of (+)-Lactose?

Suppliers quote (+)-Lactose on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle (+)-Lactose

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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