Key facts
What buyers check first
- CAS number
- 4618-18-2
- Formula
- C12H22O11
- Molar mass
- 342.30 g/mol
- EC number
- 225-027-7
- HS code
- 294000
- Category
- Respiratory, allergy and digestive drugs
What is Lactulose?
Plain description, key identifiers and synonyms
Lactulose is a synthetic galactosylfructose disaccharide used in the treatment of constipation and hepatic encephalopathy. It has a role as a laxative and a gastrointestinal drug.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (2S,3R,4S,5R,6R)-2-[(2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
- CAS number
- 4618-18-2 CAS number cross-checkedOther or deprecated CAS: 58166-24-8, 58166-25-9
- EC number
- 225-027-7
- Molecular formula
- C12H22O11
- UNII
- 9U7D5QH5AE, 9XH2P2N8EP
- INCI name
- LACTULOSE
- InChIKey
- JCQLYHFGKNRPGE-FCVZTGTOSA-N
- InChI
- InChI=1S/C12H22O11/c13-1-4-6(16)7(17)8(18)11(21-4)22-9-5(2-14)23-12(20,3-15)10(9)19/h4-11,13-20H,1-3H2/t4-,5-,6+,7+,8-,9-,10+,11+,12-/m1/s1
- Canonical SMILES
- OCC1OC(OC2C(CO)OC(O)(CO)C2O)C(O)C(O)C1O
- Isomeric SMILES
- C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@@]([C@H]2O)(CO)O)CO)O)O)O)O
Synonyms
- D-Lactulose
- Bifiteral
- Cephulac
- Chronulac
- Constilac
- Lactulosa
- Acilac
- Cholac
- Constulose
- Lactulosum
- Enulose
- Generlac
- Heptalac
- Laxilose
- Portalac
- Kristalose
- Lattulosio
- 4-O-beta-D-Galactopyranosyl-D-fructose
- Lactulose jp17
- 4-galactosyl fructose
- 4-O-beta-D-Galactopyranosyl-D-fructofuranose
- D-Fructose, 4-O-beta-D-galactopyranosyl-
- (2S,3R,4S,5R,6R)-2-{[(2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
- Osmolax
- Regulose
Show all 38 synonymsShow fewer synonyms
- Lemlax
- Laxose orange
- Duphalac Dry
- Lactulose Solution
- (2S,3R,4S,5R,6R)-2-(((2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl)oxy)-6-(hydroxymethyl)oxane-3,4,5-triol
- GlyTouCan:G57229GY
- Lactulose Solution USP, 10 g/15 mL
- beta-D-Galactopyranosyl-(1->4)-D-fructose
- 6-deoxy-3-C-methyl-D-mannose
- Evalose
- Isolactose
- Laevolac
- 4-O-beta-D-galactopyranosyl-beta-D-fructofuranose
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 342.30 g/molcalc.Computed value |
|---|---|
| Exact mass | 342.1162 Dacalc.Computed value |
| LogP (octanol/water) | -5.4calc.Computed value |
| Topological polar surface area | 189.5 Ųcalc.Computed value |
| Hydrogen bond donors | 8calc.Computed value |
| Hydrogen bond acceptors | 11calc.Computed value |
| Rotatable bonds | 5calc.Computed value |
| Heavy atoms | 23calc.Computed value |
| Rings | 2calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 1calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 9calc.Computed value |
| Lipinski rule of five | Fails (2 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Lactulose suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- ChinaUnclaimed profileLactuloseGrade, purity and minimum order on requestPrice on request
- China, HangzhouUnclaimed profileLactuloseGrade, purity and minimum order on requestPrice on request
- United StatesUnclaimed profileLactuloseGrade, purity and minimum order on requestPrice on request
- China, Linyi ManufacturerUnclaimed profileLactuloseGrade, purity and minimum order on requestPrice on request
- Germany, WaltropUnclaimed profileLactuloseGrade, purity and minimum order on requestPrice on request
- ManufacturerUnclaimed profileLactuloseGrade, purity and minimum order on requestPrice on request
- China ManufacturerUnclaimed profileLactuloseGrade, purity and minimum order on requestPrice on request
- Austria, Linz ManufacturerUnclaimed profileLactuloseGrade, purity and minimum order on requestPrice on request
- Italy, Vicchio (La Madonna ) ManufacturerUnclaimed profileLactuloseGrade, purity and minimum order on requestPrice on request
- India, Boisar ManufacturerUnclaimed profileLactuloseGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
51 suppliers in 14 countries
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Lactulose price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Use classes: Cosmetics.
Industries and functions
Cosmetic ingredient, INCI name LACTULOSE(humectant, skin conditioning)
Pharmacological actions
- Gastrointestinal Agents
Roles
- dermatologic drug
- gastrointestinal drug
- hepatoprotective agent
- laxative
- pharmaceutical
- protective agent
Functional uses
- Humectant
- Softener and conditioner
Cosmetic functions
- Humectant
- Skin conditioning
Pharmacology
Lactulose is an Osmotic Laxative. The mechanism of action of lactulose is as an Osmotic Activity and Acidifying Activity. The physiologic effect of lactulose is by means of Stimulation Large Intestine Fluid/Electrolyte Secretion.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- EU cosmetic ingredient inventory
- Active ingredient in FDA approved drug labels
United States
- TSCA inventory (USA)Status: Inactive in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Lactulose is traded under.
Sugar ethers, sugar acetals and sugar esters, and their salts, other than the products of heading 29.37…
- Germany23.7%
- China20.6%
- United States11.5%
- United States14.0%
- Japan7.4%
- Germany6.1%
The HS code shown for Lactulose is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Lactulose, based on the data on this page
What is Lactulose?
What is the CAS number of Lactulose?
What is the molecular formula and weight of Lactulose?
What is Lactulose used for?
Is Lactulose hazardous?
What is the HS code of Lactulose?
Where can I buy Lactulose?
Where can I buy Lactulose in India?
What is the price of Lactulose?
Guides for buyers
Practical guides that help when you source, ship or handle Lactulose
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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