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Skin conditioning agents and actives

Uracil

Also known as pyrimidine-2,4(1H,3H)-dione, 2,4(1H,3H)-Pyrimidinedione, Pyrod

CAS 66-22-8Formula C4H4N2O2Molar mass 112.09 g/molEC 200-621-9
GHS signal word: Warning. Pictograms: Harmful or irritant 124 suppliers listed
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Uracil chemical structure, C4H4N2O2, CAS 66-22-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
66-22-8
Formula
C4H4N2O2
Molar mass
112.09 g/mol
EC number
200-621-9
HS code
293359
Category
Skin conditioning agents and actives

What is Uracil?

Plain description, key identifiers and synonyms

Uracil is a common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription. It has a role as a prodrug, an allergen, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and a Daphnia magna metabolite. It is a pyrimidine nucleobase and a pyrimidone. It is a tautomer of a (4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1H-pyrimidine-2,4-dione
CAS number
66-22-8 CAS number cross-checkedOther or deprecated CAS: 144104-68-7, 24897-50-5, 2920-92-5, 51953-14-1, 51953-19-6, 66224-60-0, 66255-05-8
EC number
200-621-9
Molecular formula
C4H4N2O2
UNII
56HH86ZVCT
MDL number
MFCD00006016
INCI name
URACIL
InChIKey
ISAKRJDGNUQOIC-UHFFFAOYSA-N
InChI
InChI=1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)
SMILES (canonical and isomeric)
C1=CNC(=O)NC1=O

Synonyms

  • pyrimidine-2,4(1H,3H)-dione
  • 2,4(1H,3H)-Pyrimidinedione
  • Pyrod
  • Pirod
  • Hybar X
  • 2,4-Dioxopyrimidine
  • 2,4-Pyrimidinedione
  • 1H-Pyrimidine-2,4-dione
  • 1,2,3,4-tetrahydropyrimidine-2,4-dione
  • 2, 4-Dioxopyrimidine
  • 2-hydroxy-4-(1H)-pyrimidione
  • 2-hydroxy-4-(3H)-pyrimidione
  • 4-hydroxy-2-(1H)-pyrimidione
  • 2,4-Dihydroxypyrimidine
  • pyrimidine-2,4-diol
  • 2,4-Pyrimidinediol
  • RU 12709
  • 2-Hydroxy-4(3H)-pyrimidinone
  • Ura
  • 2-Hydroxy-4(1H)-pyrimidinone
  • SQ 6201
  • SQ 7726
  • SQ 8493
  • BMS 205603-01
  • 2,4-Pyrimidinediol (9CI)
Show all 34 synonyms
  • Lamivudine impurity e
  • 4-Hydroxy-2(1H)-pyrimidinone
  • Lamivudine impurity e rs
  • Fluorouracil specified compound c
  • Uracil, >=99.0% (T)
  • Uracil (usp-rs)
  • Uracil (mart.)
  • 4-Hydroxyuracil
  • 2,4(1H,3H)-Pyrimidinedione, 2,4-Dihydroxypyrimidine, 2,4-Pyrimidinediol

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
112.09 g/molcalc.
Exact mass
112.0273 Dacalc.
LogP (octanol/water)
-0.94calc.
Topological polar surface area
65.72 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
0calc.
Heavy atoms
8calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1cc[nH]c(=O)[nH]1

O=c1cc[nH]c(=O)[nH]1

1 ring, 8 atoms. This chemical is the scaffold itself.

2,933 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Uracil suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 124 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

124 suppliers in 17 countries

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Uracil price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name URACIL(skin conditioning)

Roles

  • Daphnia magna metabolite
  • Daphnia metabolite
  • Escherichia coli metabolite
  • Saccharomyces cerevisiae metabolite
  • aetiopathogenetic role
  • allergen
  • animal metabolite
  • antineoplastic agent
  • bacterial metabolite
  • crustacean metabolite
  • eukaryotic metabolite
  • fungal metabolite
  • human metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite
  • pharmaceutical
  • pro-agent
  • prodrug
  • prokaryotic metabolite

Functional uses

  • Softener and conditioner

Cosmetic functions

  • Skin conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Uracil is traded under.

HS 2933.59Indicative HS code

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other

World exports in 2024
$18.4B
+10.5% vs 2023, imports $24.8B
2019 to 2024
Top exporters
  1. Ireland43.6%
  2. Switzerland * partner reported26.3%
  3. China7.9%
Top importers
  1. Slovenia30.3%
  2. United States30.1%
  3. Germany15.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Uracil is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Uracil, based on the data on this page

What is Uracil?

Uracil is a common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription.

What is the CAS number of Uracil?

The CAS registry number of Uracil is 66-22-8. Other or deprecated CAS numbers: 144104-68-7, 24897-50-5, 2920-92-5.

What is the molecular formula and weight of Uracil?

The molecular formula of Uracil is C4H4N2O2 and its molar mass is 112.09 g/mol.

What is Uracil used for?

Known uses and roles of Uracil include skin conditioning agents in cosmetics and personal care, daphnia magna metabolite, daphnia metabolite, escherichia coli metabolite, saccharomyces cerevisiae metabolite and 18 more.

Is Uracil hazardous?

Uracil carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Uracil?

Uracil is usually classified under HS code 293359 (Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Uracil?

CompoundList lists 124 suppliers of Uracil in China, United States, Germany, United Kingdom and 13 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Uracil in India?

1 supplier in India list Uracil on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Uracil?

Suppliers quote Uracil on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Uracil

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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