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Cardiovascular and metabolic drugs

Vincamine

Also known as Pervincamine, Arteriovinca, Angiopac

CAS 1617-90-9Formula C21H26N2O3Molar mass 354.45 g/molEC 216-576-3
GHS signal word: Warning. Pictograms: Harmful or irritant 30 suppliers listed
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Vincamine chemical structure, C21H26N2O3, CAS 1617-90-9
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Yellow crystals from acetone or methanol
Melting point
232 to 233
Solubility
In water, 62 mg/L @ 25 °C /Estimated/
HS code
293979
Category
Cardiovascular and metabolic drugs
Illustrative photo, yellow pigment powder in a glass jar on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Vincamine?

Plain description, key identifiers and synonyms

Vincamine is a methyl ester, a vinca alkaloid, an organic heteropentacyclic compound, an alkaloid ester and a hemiaminal. It has a role as a metabolite, a vasodilator agent and an antihypertensive agent. It is functionally related to an eburnamenine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
methyl (15S,17S,19S)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate
CAS number
1617-90-9 CAS number cross-checked
EC number
216-576-3
Molecular formula
C21H26N2O3
UNII
996XVD0JHT
MDL number
MFCD00078054
InChIKey
RXPRRQLKFXBCSJ-GIVPXCGWSA-N
InChI
InChI=1S/C21H26N2O3/c1-3-20-10-6-11-22-12-9-15-14-7-4-5-8-16(14)23(17(15)18(20)22)21(25,13-20)19(24)26-2/h4-5,7-8,18,25H,3,6,9-13H2,1-2H3/t18-,20+,21+/m1/s1
Canonical SMILES
CCC12CCCN3CCc4c(n(c5ccccc45)C(O)(C(=O)OC)C1)C32
Isomeric SMILES
CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4[C@](C2)(C(=O)OC)O

Synonyms

  • Pervincamine
  • Arteriovinca
  • Angiopac
  • Vincafor
  • Vincamidol
  • Novicet
  • Methyl vincaminate
  • Oxygeron
  • Vincagil
  • Equipur
  • Vincafolina
  • Tripervan
  • Vincadar
  • Ocu-vinc
  • Vincamina
  • Vincimax
  • Perval
  • Pervone
  • Vincaminum
  • Vraap
  • Vinodrel retard
  • Cetal retard
  • Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3alpha,14beta,16alpha)-
  • methyl (15S,17S,19S)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate
  • methyl 14beta-hydroxy-14,15-dihydro-3alpha,16alpha-eburnamenine-14alpha-carboxylate
Show all 38 synonyms
  • methyl (15S,17S,19S)-15-ethyl-17-hydroxy-1,11-diazapentacyclo(9.6.2.0^(2,7).0^(8,18).0^(15,19))nonadeca-2,4,6,8(18)-tetraene-17-carboxylate
  • methyl (15S,17S,19S)-15-ethyl-17-hydroxy-1,11-diazapentacyclo(9.6.2.02,7.08,18.015,19)nonadeca-2,4,6,8(18)-tetraene-17-carboxylate
  • methyl (15S,17S,19S)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.0^{2,7}.0^{8,18}.0^{15,19}]nonadeca-2,4,6,8(18)-tetraene-17-carboxylate
  • Devincan
  • Minorine
  • (+)-Vincamine
  • Vincamin
  • Anasclerol
  • Monorin
  • Devinkan
  • Vincasaunier
  • Decincan
  • Vincapront

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Yellow crystals from acetone or methanolexp.
Melting point
232 to 233exp.
Solubility
In water, 62 mg/L @ 25 °C /Estimated/exp.
Vapour pressure
1.1 × 10⁻¹² mm Hg @ 25 °C /Estimated/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
354.45 g/molcalc.
Exact mass
354.1943 Dacalc.
LogP (octanol/water)
2.95calc.
Topological polar surface area
54.7 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
2calc.
Heavy atoms
26calc.
Rings
5calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.57calc.
Formal charge
0calc.
Stereocentres
3calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)c1c3n2CCC2CCCN(CC1)C32

c1ccc2c(c1)c1c3n2CCC2CCCN(CC1)C32

5 rings, 19 atoms.

50 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Vincamine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 30 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

30 suppliers in 8 countries

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Vincamine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Medication: vasodilator.

Pharmacological actions

  • Antihypertensive Agents
  • Vasodilator Agents

Roles

  • antihypertensive agent
  • cardiovascular drug
  • metabolite
  • pharmaceutical
  • vasodilator agent

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Vincamine is traded under.

HS 2939.79Indicative HS code

Alkaloids of vegetal origin, other than cocaine, ecgonine, salts, esters and other derivatives, not elsewhere…

World exports in 2024
$701M
+18.9% vs 2023, imports $830M
2019 to 2024
Top exporters
  1. Switzerland * partner reported25.3%
  2. Germany21.4%
  3. India * partner reported14.9%
Top importers
  1. United States20.9%
  2. Germany14.7%
  3. Italy14.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Vincamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Vincamine, based on the data on this page

What is Vincamine?

Vincamine is a methyl ester, a vinca alkaloid, an organic heteropentacyclic compound, an alkaloid ester and a hemiaminal. It has a role as a metabolite, a vasodilator agent and an antihypertensive agent. It is functionally related to an eburnamenine.

What is the CAS number of Vincamine?

The CAS registry number of Vincamine is 1617-90-9.

What is the molecular formula and weight of Vincamine?

The molecular formula of Vincamine is C21H26N2O3 and its molar mass is 354.45 g/mol.

What is Vincamine used for?

Medication: vasodilator.

Is Vincamine hazardous?

Vincamine carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Vincamine?

Vincamine is usually classified under HS code 293979 (Alkaloids, natural or reproduced by synthesis, and their salts, ethers, esters and other…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Vincamine?

CompoundList lists 30 suppliers of Vincamine in China, United States, Germany, Romania and 4 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Vincamine in India?

1 supplier in India list Vincamine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Vincamine?

Suppliers quote Vincamine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Vincamine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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