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Cardiovascular and metabolic drugs

Xipamide

Also known as Diurexan, Xipamid, Xipamida

CAS 14293-44-8Formula C15H15ClN2O4SMolar mass 354.82 g/molEC 238-216-4
GHS signal word: Warning. Pictograms: Harmful or irritant 11 suppliers listed
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Xipamide chemical structure, C15H15ClN2O4S, CAS 14293-44-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
14293-44-8
Formula
C15H15ClN2O4S
Molar mass
354.82 g/mol
EC number
238-216-4
HS code
293590
Category
Cardiovascular and metabolic drugs

What is Xipamide?

Plain description, key identifiers and synonyms

Xipamide is a member of benzamides.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide
CAS number
14293-44-8 CAS number cross-checked
EC number
238-216-4
Molecular formula
C15H15ClN2O4S
UNII
4S9EY0NUEC
MDL number
MFCD00865927
InChIKey
MTZBBNMLMNBNJL-UHFFFAOYSA-N
InChI
InChI=1S/C15H15ClN2O4S/c1-8-4-3-5-9(2)14(8)18-15(20)10-6-13(23(17,21)22)11(16)7-12(10)19/h3-7,19H,1-2H3,(H,18,20)(H2,17,21,22)
SMILES (canonical and isomeric)
CC1=C(C(=CC=C1)C)NC(=O)C2=CC(=C(C=C2O)Cl)S(=O)(=O)N

Synonyms

  • Diurexan
  • Xipamid
  • Xipamida
  • Xipamidum
  • MJF 10,938
  • 4-Chloro-5-sulfamoyl-2',6'-salicyloxylidide
  • Benzamide, 5-(aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-
  • 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide
  • Aquaphor
  • Diurex (lacer)
  • Aquaphor (diuretic)
  • Be 1293
  • 2',6'-Salicyloxylidide, 4-chloro-5-sulfamoyl-
  • 4-Chlor-5-sulfamoyl-2',6'-salicyloxylidid
  • Xipamide (USAN)
  • Aquaphoril
  • Zipix
  • Benzamide,5-(aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-
  • Chronexan
  • MJF 10938
  • Lumitens
  • Xipamide (Standard)
  • 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoyl-benzamide
  • 5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxybenzamide
  • 5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-benzamide
Show all 27 synonyms
  • 4-Chloro-5-sulfamoyl-2',6'-salicyloxilidide
  • 4-Chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulphamoylbenzamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
354.82 g/molcalc.
Exact mass
354.0441 Dacalc.
LogP (octanol/water)
2.56calc.
Topological polar surface area
109.5 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
3calc.
Heavy atoms
23calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.13calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(Nc1ccccc1)c1ccccc1

O=C(Nc1ccccc1)c1ccccc1

2 rings, 15 atoms, the Benzanilide ring system.

13,118 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Xipamide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 11 suppliers
11 of 11 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

11 suppliers in 4 countries

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Xipamide price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Industries and functions

Pharmacological actions

  • Antihypertensive Agents
  • Diuretics

Roles

  • cardiovascular drug
  • pharmaceutical

Pharmacology

Xipamide is a sulfonamide-based diuretic. Xipamide acts on the distal convoluted tubules. In addition, this agent has a weak inhibitory effect on carbonic anyydrase (CA).

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Xipamide is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Xipamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Xipamide, based on the data on this page

What is Xipamide?

Xipamide is a member of benzamides.

What is the CAS number of Xipamide?

The CAS registry number of Xipamide is 14293-44-8.

What is the molecular formula and weight of Xipamide?

The molecular formula of Xipamide is C15H15ClN2O4S and its molar mass is 354.82 g/mol.

What is Xipamide used for?

Known uses and roles of Xipamide include antihypertensives in pharmaceuticals, cardiovascular drug, pharmaceutical, antihypertensive agents and diuretics.

Is Xipamide hazardous?

Xipamide carries the GHS signal word "Warning". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Xipamide?

Xipamide is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Xipamide?

CompoundList lists 11 suppliers of Xipamide in China, United States, India and Romania. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Xipamide in India?

1 supplier in India list Xipamide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Xipamide?

Suppliers quote Xipamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Xipamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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