Murcko scaffold
Ring system with 2 rings and 18 atoms
7 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 18
- Chemicals
- 7
- With full pages
- 1
Scaffold SMILES
O=C(OCCCN1CCOCC1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 7 of 7 chemicals
AF-398
CAS 60439-45-4C18H27NO6
Benzoic acid, 3,4,5-trimethoxy-, 3-morpholinopropyl ester
CAS 60439-46-5C17H25NO6
3-(Morpholin-4-yl)propyl 4-fluoro-3-iodobenzoate--hydrogen chloride (1/1)
CAS 63916-82-5C14H18ClFINO3
2,2-Dimethyl-3-(morpholin-4-yl)propyl benzoate--hydrogen chloride (1/1)
CAS 67049-55-2C16H24ClNO3
Benzoic acid, p-(butylamino)-, 2-hydroxy-3-morpholinopropyl ester, hydrochloride
CAS 100311-24-8C18H29ClN2O4
2-Hydroxy-3-(morpholin-4-yl)propyl 4-(propylamino)benzoate--hydrogen chloride (1/1)
CAS 100482-38-0C17H27ClN2O4
Benzoic acid, 3,4,5-trimethoxy-, 3-morpholinopropyl ester, hydrochloride
CAS 108479-29-4C17H26ClNO6
Related scaffolds
Same ring framework with different atoms or bond orders
S=C(NN=Cc1ccccc1)Nc1ccccc1105 chemicals
S=C(NCCc1ccccc1)Nc1ccccc160 chemicals
c1ccc(CCNCCc2ccccc2)cc158 chemicals
O=C(COc1ccccc1)NCc1ccccc146 chemicals
O=C(NCCOc1ccccc1)c1ccccc146 chemicals
O=C(C=Cc1ccccc1)NCc1ccccc143 chemicals
c1ccc(OCCCOc2ccccc2)cc141 chemicals
O=C(CC(=O)Nc1ccccc1)Nc1ccccc137 chemicals
O=C(CNS(=O)(=O)c1ccccc1)Nc1ccccc136 chemicals
O=C(CSCc1ccccc1)Nc1ccccc133 chemicals
O=C(Cc1ccccc1)NCCc1ccccc132 chemicals
O=C(CNCc1ccccc1)Nc1ccccc131 chemicals