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Murcko scaffold

Ring system with 3 rings and 27 atoms

26 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
26
With full pages
3
Scaffold SMILES

O=C(CN(c1ccccc1)S(=O)(=O)c1ccccc1)NCc1ccncc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN(c1ccccc1)S(=O)(=O)c1ccccc1)NCc1ccncc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

2-{2-Methoxy-5-methyl[(4-methylphenyl)sulfonyl]anilino}-N-(4-pyridinylmethyl)acetamide chemical structure, C23H25N3O4S, CAS 428483-08-3
2-{2-Methoxy-5-methyl[(4-methylphenyl)sulfonyl]anilino}-N-(4-pyridinylmethyl)acetamide
CAS 428483-08-3C23H25N3O4S
2-(2-Methoxy-N-(4-methoxyphenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide chemical structure, C22H23N3O5S, CAS 528562-62-1
2-(2-Methoxy-N-(4-methoxyphenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide
CAS 528562-62-1C22H23N3O5S
2-(N-(3,4-Dimethoxyphenyl)sulfonyl-4-ethoxyanilino)-N-(pyridin-4-ylmethyl)acetamide chemical structure, C24H27N3O6S, CAS 510723-14-5
2-(N-(3,4-Dimethoxyphenyl)sulfonyl-4-ethoxyanilino)-N-(pyridin-4-ylmethyl)acetamide
CAS 510723-14-5C24H27N3O6S
2-(N-(3-Chloro-4-methoxyphenyl)phenylsulfonamido)-N-(pyridin-4-ylmethyl)acetamide chemical structure, C21H20ClN3O4S, CAS 695174-96-0
2-(N-(3-Chloro-4-methoxyphenyl)phenylsulfonamido)-N-(pyridin-4-ylmethyl)acetamide
CAS 695174-96-0C21H20ClN3O4S
N~2~-(3,4-dimethylphenyl)-N~2~-(phenylsulfonyl)-N-(pyridin-4-ylmethyl)glycinamide chemical structure, C22H23N3O3S, CAS 6073-79-6
N~2~-(3,4-dimethylphenyl)-N~2~-(phenylsulfonyl)-N-(pyridin-4-ylmethyl)glycinamide
CAS 6073-79-6C22H23N3O3S
2-(4-Methoxy-N-(4-methylphenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide chemical structure, C22H23N3O4S, CAS 331639-01-1
2-(4-Methoxy-N-(4-methylphenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide
CAS 331639-01-1C22H23N3O4S
2-(5-Chloro-2-methoxy-N-(4-methylphenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide chemical structure, C22H22ClN3O4S, CAS 312291-08-0
2-(5-Chloro-2-methoxy-N-(4-methylphenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide
CAS 312291-08-0C22H22ClN3O4S
2-[N-(Benzenesulfonyl)-2-methylanilino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C21H21N3O3S, CAS 331638-91-6
2-[N-(Benzenesulfonyl)-2-methylanilino]-N-(pyridin-4-ylmethyl)acetamide
CAS 331638-91-6C21H21N3O3S
2-[N-(Benzenesulfonyl)-4-methoxyanilino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C21H21N3O4S, CAS 443668-19-7
2-[N-(Benzenesulfonyl)-4-methoxyanilino]-N-(pyridin-4-ylmethyl)acetamide
CAS 443668-19-7C21H21N3O4S
2-[N-(Benzenesulfonyl)-5-chloro-2-methylanilino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C21H20ClN3O3S, CAS 335211-30-8
2-[N-(Benzenesulfonyl)-5-chloro-2-methylanilino]-N-(pyridin-4-ylmethyl)acetamide
CAS 335211-30-8C21H20ClN3O3S
2-[(3-Chloro-4-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-pyridinylmethyl)acetamide chemical structure, C22H22ClN3O4S, CAS 367920-41-0
2-[(3-Chloro-4-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-pyridinylmethyl)acetamide
CAS 367920-41-0C22H22ClN3O4S
2-(4-Chloro-N-(4-methylphenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide chemical structure, C21H20ClN3O3S, CAS 335394-37-1
2-(4-Chloro-N-(4-methylphenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide
CAS 335394-37-1C21H20ClN3O3S
Cambridge id 6458492 chemical structure, C21H20FN3O3S, CAS 333747-59-4
Cambridge id 6458492
CAS 333747-59-4C21H20FN3O3S
N~2~-(3-methoxyphenyl)-N~2~-[(4-methylphenyl)sulfonyl]-N-(pyridin-4-ylmethyl)glycinamide chemical structure, C22H23N3O4S, CAS 335208-69-0
N~2~-(3-methoxyphenyl)-N~2~-[(4-methylphenyl)sulfonyl]-N-(pyridin-4-ylmethyl)glycinamide
CAS 335208-69-0C22H23N3O4S
2-[N-(Benzenesulfonyl)-3,5-dimethylanilino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C22H23N3O3S, CAS 426231-43-8
2-[N-(Benzenesulfonyl)-3,5-dimethylanilino]-N-(pyridin-4-ylmethyl)acetamide
CAS 426231-43-8C22H23N3O3S
2-[2,3-Dichloro(phenylsulfonyl)anilino]-N-(4-pyridinylmethyl)acetamide chemical structure, C20H17Cl2N3O3S, CAS 722464-16-6
2-[2,3-Dichloro(phenylsulfonyl)anilino]-N-(4-pyridinylmethyl)acetamide
CAS 722464-16-6C20H17Cl2N3O3S
2-(N-(4-Fluorophenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide chemical structure, C20H18FN3O3S, CAS 831241-60-2
2-(N-(4-Fluorophenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide
CAS 831241-60-2C20H18FN3O3S
2-(N-(4-Chlorophenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide chemical structure, C20H18ClN3O3S, CAS 530125-93-0
2-(N-(4-Chlorophenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide
CAS 530125-93-0C20H18ClN3O3S
2-(3-Chloro-N-(4-chlorophenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide chemical structure, C20H17Cl2N3O3S, CAS 535942-71-3
2-(3-Chloro-N-(4-chlorophenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide
CAS 535942-71-3C20H17Cl2N3O3S
2-(Benzenesulfonyl-(2-chloro-5-trifluoromethyl-phenyl)-amino)-N-pyridin-4-ylmethyl-acetamide chemical structure, C21H17ClF3N3O3S, CAS 432018-03-6
2-(Benzenesulfonyl-(2-chloro-5-trifluoromethyl-phenyl)-amino)-N-pyridin-4-ylmethyl-acetamide
CAS 432018-03-6C21H17ClF3N3O3S
2-(3-Chloro-4-methyl-N-(4-methylphenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide chemical structure, C22H22ClN3O3S, CAS 426221-39-8
2-(3-Chloro-4-methyl-N-(4-methylphenyl)sulfonylanilino)-N-(pyridin-4-ylmethyl)acetamide
CAS 426221-39-8C22H22ClN3O3S
2-[N-(Benzenesulfonyl)-3-chloroanilino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C20H18ClN3O3S, CAS 312495-37-7
2-[N-(Benzenesulfonyl)-3-chloroanilino]-N-(pyridin-4-ylmethyl)acetamide
CAS 312495-37-7C20H18ClN3O3S
RefChem:382085 chemical structure, C22H19ClF3N3O3S, CAS 6401-23-6
RefChem:382085
CAS 6401-23-6C22H19ClF3N3O3S
2-[N-(Benzenesulfonyl)-2-chloroanilino]-N-(pyridin-4-ylmethyl)acetamide chemical structure, C20H18ClN3O3S, CAS 367959-49-7
2-[N-(Benzenesulfonyl)-2-chloroanilino]-N-(pyridin-4-ylmethyl)acetamide
CAS 367959-49-7C20H18ClN3O3S