CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 18 atoms

33 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
33
With full pages
5
Scaffold SMILES

O=c1cc(Oc2ccccc2)nc2ccccn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(Oc2ccccc2)nc2ccccn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

(E)-Methyl 2-cyano-3-(4-oxo-2-phenoxy-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate chemical structure, C19H13N3O4, CAS 620104-47-4
(E)-Methyl 2-cyano-3-(4-oxo-2-phenoxy-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate
CAS 620104-47-4C19H13N3O4
(E)-2-Cyano-3-(9-methyl-4-oxo-2-phenoxypyrido[1,2-a]pyrimidin-3-yl)prop-2-enamide chemical structure, C19H14N4O3, CAS 620110-71-6
(E)-2-Cyano-3-(9-methyl-4-oxo-2-phenoxypyrido[1,2-a]pyrimidin-3-yl)prop-2-enamide
CAS 620110-71-6C19H14N4O3
2-(4-Fluorophenoxy)-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C15H9FN2O3, CAS 879907-11-6
2-(4-Fluorophenoxy)-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 879907-11-6C15H9FN2O3
2-(4-Fluorophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C16H11FN2O3, CAS 879906-49-7
2-(4-Fluorophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 879906-49-7C16H11FN2O3
9-Methyl-4-oxo-2-(m-tolyloxy)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde chemical structure, C17H14N2O3, CAS 879906-50-0
9-Methyl-4-oxo-2-(m-tolyloxy)-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde
CAS 879906-50-0C17H14N2O3
(E)-3-(2-(4-Chlorophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-cyanoacrylamide chemical structure, C19H13ClN4O3, CAS 620112-27-8
(E)-3-(2-(4-Chlorophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-cyanoacrylamide
CAS 620112-27-8C19H13ClN4O3
Methyl (2E)-2-cyano-3-[2-(4-methoxyphenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]prop-2-enoate chemical structure, C21H17N3O5, CAS 620111-97-9
Methyl (2E)-2-cyano-3-[2-(4-methoxyphenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]prop-2-enoate
CAS 620111-97-9C21H17N3O5
(E)-Methyl 2-cyano-3-(9-methyl-4-oxo-2-(m-tolyloxy)-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate chemical structure, C21H17N3O4, CAS 620112-60-9
(E)-Methyl 2-cyano-3-(9-methyl-4-oxo-2-(m-tolyloxy)-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate
CAS 620112-60-9C21H17N3O4
(E)-Methyl 2-cyano-3-(2-(4-fluorophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate chemical structure, C20H14FN3O4, CAS 620113-55-5
(E)-Methyl 2-cyano-3-(2-(4-fluorophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate
CAS 620113-55-5C20H14FN3O4
(E)-Methyl 3-(2-(4-bromophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-cyanoacrylate chemical structure, C20H14BrN3O4, CAS 620111-34-4
(E)-Methyl 3-(2-(4-bromophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-cyanoacrylate
CAS 620111-34-4C20H14BrN3O4
Ethyl (E)-2-cyano-3-[2-(3-methylphenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]prop-2-enoate chemical structure, C21H17N3O4, CAS 620106-40-3
Ethyl (E)-2-cyano-3-[2-(3-methylphenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]prop-2-enoate
CAS 620106-40-3C21H17N3O4
(E)-3-(2-(4-Chlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-cyanoacrylamide chemical structure, C18H11ClN4O3, CAS 620106-07-2
(E)-3-(2-(4-Chlorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-cyanoacrylamide
CAS 620106-07-2C18H11ClN4O3
(E)-Methyl 3-(2-(4-chlorophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-cyanoacrylate chemical structure, C20H14ClN3O4, CAS 620112-28-9
(E)-Methyl 3-(2-(4-chlorophenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)-2-cyanoacrylate
CAS 620112-28-9C20H14ClN3O4
(E)-Methyl 2-cyano-3-(2-(4-ethylphenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate chemical structure, C21H17N3O4, CAS 620106-72-1
(E)-Methyl 2-cyano-3-(2-(4-ethylphenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate
CAS 620106-72-1C21H17N3O4
2-Cyano-N-ethyl-3-[2-(4-methoxyphenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]prop-2-enamide chemical structure, C21H18N4O4, CAS 5281-63-0
2-Cyano-N-ethyl-3-[2-(4-methoxyphenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]prop-2-enamide
CAS 5281-63-0C21H18N4O4
2-Cyano-3-[9-methyl-2-(4-methylphenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]-N-(3-propan-2-yloxypropyl)prop-2-enamide chemical structure, C26H28N4O4, CAS 5267-21-0
2-Cyano-3-[9-methyl-2-(4-methylphenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]-N-(3-propan-2-yloxypropyl)prop-2-enamide
CAS 5267-21-0C26H28N4O4
3-[2-(4-Chloro-3-methylphenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]-2-cyano-N-(prop-2-en-1-yl)prop-2-enamide chemical structure, C22H17ClN4O3, CAS 5268-30-4
3-[2-(4-Chloro-3-methylphenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]-2-cyano-N-(prop-2-en-1-yl)prop-2-enamide
CAS 5268-30-4C22H17ClN4O3
(E)-Methyl 2-cyano-3-(4-oxo-2-(m-tolyloxy)-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate chemical structure, C20H15N3O4, CAS 620106-39-0
(E)-Methyl 2-cyano-3-(4-oxo-2-(m-tolyloxy)-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate
CAS 620106-39-0C20H15N3O4
Methyl (2E)-3-[2-(4-tert-butylphenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]-2-cyanoprop-2-enoate chemical structure, C23H21N3O4, CAS 620104-79-2
Methyl (2E)-3-[2-(4-tert-butylphenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl]-2-cyanoprop-2-enoate
CAS 620104-79-2C23H21N3O4
(E)-Methyl 2-cyano-3-(2-(2,3-dimethylphenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate chemical structure, C21H17N3O4, CAS 620109-17-3
(E)-Methyl 2-cyano-3-(2-(2,3-dimethylphenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate
CAS 620109-17-3C21H17N3O4
Methyl (E)-2-cyano-3-[2-(3,5-dimethylphenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]prop-2-enoate chemical structure, C21H17N3O4, CAS 620108-62-5
Methyl (E)-2-cyano-3-[2-(3,5-dimethylphenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]prop-2-enoate
CAS 620108-62-5C21H17N3O4
(E)-Methyl 2-cyano-3-(2-(2,4-dimethylphenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate chemical structure, C22H19N3O4, CAS 620538-35-4
(E)-Methyl 2-cyano-3-(2-(2,4-dimethylphenoxy)-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate
CAS 620538-35-4C22H19N3O4
(E)-Methyl 2-cyano-3-(4-oxo-2-(p-tolyloxy)-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate chemical structure, C20H15N3O4, CAS 620105-36-4
(E)-Methyl 2-cyano-3-(4-oxo-2-(p-tolyloxy)-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylate
CAS 620105-36-4C20H15N3O4
(E)-2-Cyano-3-(2-(2-fluorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide chemical structure, C18H11FN4O3, CAS 620107-64-4
(E)-2-Cyano-3-(2-(2-fluorophenoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acrylamide
CAS 620107-64-4C18H11FN4O3