CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 20 atoms

233 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
233
With full pages
24
Scaffold SMILES

O=c1c(S(=O)(=O)c2ccccc2)c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(S(=O)(=O)c2ccccc2)c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 233 chemicals

3-[(4-Chlorophenyl)sulfonyl]-6-fluoroquinolin-4(1H)-one chemical structure, C15H9ClFNO3S, CAS 866727-75-5
3-[(4-Chlorophenyl)sulfonyl]-6-fluoroquinolin-4(1H)-one
CAS 866727-75-5C15H9ClFNO3S
6-Chloro-3-[(4-fluorophenyl)sulfonyl]quinolin-4(1H)-one chemical structure, C15H9ClFNO3S, CAS 866727-77-7
6-Chloro-3-[(4-fluorophenyl)sulfonyl]quinolin-4(1H)-one
CAS 866727-77-7C15H9ClFNO3S
6-Ethoxy-3-(4-methylphenyl)sulfonyl-1H-quinolin-4-one chemical structure, C18H17NO4S, CAS 866812-28-4
6-Ethoxy-3-(4-methylphenyl)sulfonyl-1H-quinolin-4-one
CAS 866812-28-4C18H17NO4S
6-Ethoxy-3-(4-methoxyphenyl)sulfonyl-1H-quinolin-4-one chemical structure, C18H17NO5S, CAS 866813-34-5
6-Ethoxy-3-(4-methoxyphenyl)sulfonyl-1H-quinolin-4-one
CAS 866813-34-5C18H17NO5S
3-[(4-tert-Butylphenyl)sulfonyl]-6-methylquinolin-4(1H)-one chemical structure, C20H21NO3S, CAS 872199-92-3
3-[(4-tert-Butylphenyl)sulfonyl]-6-methylquinolin-4(1H)-one
CAS 872199-92-3C20H21NO3S
3-(4-tert-Butylphenyl)sulfonyl-6-ethoxy-1H-quinolin-4-one chemical structure, C21H23NO4S, CAS 872199-94-5
3-(4-tert-Butylphenyl)sulfonyl-6-ethoxy-1H-quinolin-4-one
CAS 872199-94-5C21H23NO4S
3-(4-tert-Butylphenyl)sulfonyl-6,7-dimethoxy-1H-quinolin-4-one chemical structure, C21H23NO5S, CAS 872199-95-6
3-(4-tert-Butylphenyl)sulfonyl-6,7-dimethoxy-1H-quinolin-4-one
CAS 872199-95-6C21H23NO5S
6,7-Dimethoxy-3-tosylquinolin-4(1H)-one chemical structure, C18H17NO5S, CAS 866843-67-6
6,7-Dimethoxy-3-tosylquinolin-4(1H)-one
CAS 866843-67-6C18H17NO5S
6-Chloro-3-(4-methoxybenzenesulfonyl)-1,4-dihydroquinolin-4-one chemical structure, C16H12ClNO4S, CAS 866847-03-2
6-Chloro-3-(4-methoxybenzenesulfonyl)-1,4-dihydroquinolin-4-one
CAS 866847-03-2C16H12ClNO4S
6-Ethoxy-3-(4-ethoxyphenyl)sulfonyl-1H-quinolin-4-one chemical structure, C19H19NO5S, CAS 866847-05-4
6-Ethoxy-3-(4-ethoxyphenyl)sulfonyl-1H-quinolin-4-one
CAS 866847-05-4C19H19NO5S
3-(4-Ethoxyphenyl)sulfonyl-6,7-dimethoxy-1H-quinolin-4-one chemical structure, C19H19NO6S, CAS 866865-97-6
3-(4-Ethoxyphenyl)sulfonyl-6,7-dimethoxy-1H-quinolin-4-one
CAS 866865-97-6C19H19NO6S
6-Ethoxy-3-(4-propan-2-ylphenyl)sulfonyl-1H-quinolin-4-one chemical structure, C20H21NO4S, CAS 866866-91-3
6-Ethoxy-3-(4-propan-2-ylphenyl)sulfonyl-1H-quinolin-4-one
CAS 866866-91-3C20H21NO4S
3-(4-Chlorobenzenesulfonyl)-6-fluoro-1-methyl-1,4-dihydroquinolin-4-one chemical structure, C16H11ClFNO3S, CAS 897615-99-5
3-(4-Chlorobenzenesulfonyl)-6-fluoro-1-methyl-1,4-dihydroquinolin-4-one
CAS 897615-99-5C16H11ClFNO3S
3-(4-Ethylphenyl)sulfonyl-1-methylquinolin-4-one chemical structure, C18H17NO3S, CAS 899215-09-9
3-(4-Ethylphenyl)sulfonyl-1-methylquinolin-4-one
CAS 899215-09-9C18H17NO3S
1-Ethyl-3-(4-ethylphenyl)sulfonylquinolin-4-one chemical structure, C19H19NO3S, CAS 899213-01-5
1-Ethyl-3-(4-ethylphenyl)sulfonylquinolin-4-one
CAS 899213-01-5C19H19NO3S
6,7-Difluoro-3-(phenylsulfonyl)quinolin-4(1H)-one chemical structure, C15H9F2NO3S, CAS 899348-47-1
6,7-Difluoro-3-(phenylsulfonyl)quinolin-4(1H)-one
CAS 899348-47-1C15H9F2NO3S
6,7-Difluoro-3-[(4-methylphenyl)sulfonyl]quinolin-4(1H)-one chemical structure, C16H11F2NO3S, CAS 899348-48-2
6,7-Difluoro-3-[(4-methylphenyl)sulfonyl]quinolin-4(1H)-one
CAS 899348-48-2C16H11F2NO3S
3-[(2,5-Dimethylphenyl)sulfonyl]-6,7-difluoroquinolin-4(1H)-one chemical structure, C17H13F2NO3S, CAS 899348-49-3
3-[(2,5-Dimethylphenyl)sulfonyl]-6,7-difluoroquinolin-4(1H)-one
CAS 899348-49-3C17H13F2NO3S
3-[(4-Ethylphenyl)sulfonyl]-6,7-difluoroquinolin-4(1H)-one chemical structure, C17H13F2NO3S, CAS 902298-06-0
3-[(4-Ethylphenyl)sulfonyl]-6,7-difluoroquinolin-4(1H)-one
CAS 902298-06-0C17H13F2NO3S
3-((3,4-Dimethylphenyl)sulfonyl)-6-methoxyquinolin-4(1H)-one chemical structure, C18H17NO4S, CAS 902506-41-6
3-((3,4-Dimethylphenyl)sulfonyl)-6-methoxyquinolin-4(1H)-one
CAS 902506-41-6C18H17NO4S
3-((4-Ethylphenyl)sulfonyl)-6,7-difluoro-1-methylquinolin-4(1H)-one chemical structure, C18H15F2NO3S, CAS 902618-52-4
3-((4-Ethylphenyl)sulfonyl)-6,7-difluoro-1-methylquinolin-4(1H)-one
CAS 902618-52-4C18H15F2NO3S
3-((2,5-Dimethylphenyl)sulfonyl)-6,7-difluoro-1-methylquinolin-4(1H)-one chemical structure, C18H15F2NO3S, CAS 902299-42-7
3-((2,5-Dimethylphenyl)sulfonyl)-6,7-difluoro-1-methylquinolin-4(1H)-one
CAS 902299-42-7C18H15F2NO3S
1-Butyl-3-[(2,5-dimethylphenyl)sulfonyl]-6,7-difluoroquinolin-4(1H)-one chemical structure, C21H21F2NO3S, CAS 902618-60-4
1-Butyl-3-[(2,5-dimethylphenyl)sulfonyl]-6,7-difluoroquinolin-4(1H)-one
CAS 902618-60-4C21H21F2NO3S
3-((4-Chlorophenyl)sulfonyl)-6-methoxy-1-methylquinolin-4(1H)-one chemical structure, C17H14ClNO4S, CAS 899214-75-6
3-((4-Chlorophenyl)sulfonyl)-6-methoxy-1-methylquinolin-4(1H)-one
CAS 899214-75-6C17H14ClNO4S