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Murcko scaffold

Ring system with 3 rings and 17 atoms

111 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
111
With full pages
33
Scaffold SMILES

O=c1cc[nH]c2cc(N3CCNCC3)ccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc[nH]c2cc(N3CCNCC3)ccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 111 of 111 chemicals

7-(4-Ethylpiperazin-1-yl)-6-fluoro-1-methyl-4-oxoquinoline-3-carbonitrile chemical structure, C17H19FN4O, CAS 1359864-63-3
7-(4-Ethylpiperazin-1-yl)-6-fluoro-1-methyl-4-oxoquinoline-3-carbonitrile
CAS 1359864-63-3C17H19FN4O
1-Ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxoquinoline-3-carbonitrile chemical structure, C18H21FN4O, CAS 1359864-69-9
1-Ethyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxoquinoline-3-carbonitrile
CAS 1359864-69-9C18H21FN4O
1-Ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carbothioamide chemical structure, C17H21FN4OS, CAS 1546989-43-8
1-Ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carbothioamide
CAS 1546989-43-8C17H21FN4OS
Norfloxacin piperazinyl-1-oxide chemical structure, C16H18FN3O4, CAS 1796931-70-8
Norfloxacin piperazinyl-1-oxide
CAS 1796931-70-8C16H18FN3O4
Norfloxacin isopropyl ester chemical structure, C19H24FN3O3, CAS 1415841-37-0
Norfloxacin isopropyl ester
CAS 1415841-37-0C19H24FN3O3
Norfloxacin dihydrate chemical structure, C16H22FN3O5, CAS 316381-81-4
Norfloxacin dihydrate
CAS 316381-81-4C16H22FN3O5
Pefloxacin-d3 chemical structure, C17H20FN3O3, CAS 2733455-58-6
Pefloxacin-d3
CAS 2733455-58-6C17H20FN3O3
N,O-Desmethylene O1-ethyl marbofloxacin chemical structure, C18H23FN4O4, CAS 2249835-04-7
N,O-Desmethylene O1-ethyl marbofloxacin
CAS 2249835-04-7C18H23FN4O4
7-[4-(2-Cyanoacetyl)piperazin-1-yl]-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid chemical structure, C19H19FN4O4, CAS 2379995-76-1
7-[4-(2-Cyanoacetyl)piperazin-1-yl]-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS 2379995-76-1C19H19FN4O4
(Z)-1-Ethyl-6-fluoro-N'-hydroxy-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboximidamide chemical structure, C17H22FN5O2, CAS 2321338-29-6
(Z)-1-Ethyl-6-fluoro-N'-hydroxy-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboximidamide
CAS 2321338-29-6C17H22FN5O2
Ethyl 1-amino-6,8-difluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylate chemical structure, C17H20F2N4O3, CAS 181427-31-6
Ethyl 1-amino-6,8-difluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylate
CAS 181427-31-6C17H20F2N4O3
Zinc norfloxacin chemical structure, C32H34F2N6O6Zn, CAS 106208-13-3
Zinc norfloxacin
CAS 106208-13-3C32H34F2N6O6Zn
Methyl 7-[4-(2,2-dimethyl-1-oxopropyl)-1-piperazinyl]-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate chemical structure, C22H28FN3O4, CAS 1160239-62-2
Methyl 7-[4-(2,2-dimethyl-1-oxopropyl)-1-piperazinyl]-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate
CAS 1160239-62-2C22H28FN3O4
6-Fluoro-8-hydroxy-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride chemical structure, C16H20ClFN4O4, CAS 2253640-08-1
6-Fluoro-8-hydroxy-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
CAS 2253640-08-1C16H20ClFN4O4
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-(1-oxooctadecyl)-1-piperazinyl]-3-quinolinecarboxylic Acid chemical structure, C34H52FN3O4, CAS 1911573-08-4
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-(1-oxooctadecyl)-1-piperazinyl]-3-quinolinecarboxylic Acid
CAS 1911573-08-4C34H52FN3O4