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Murcko scaffold

1-Phenylisoquinolin-3(2H)-one scaffold

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
18
With full pages
0
Scaffold SMILES

O=c1cc2ccccc2c(-c2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenylisoquinolin-3(2H)-one page
Murcko scaffold O=c1cc2ccccc2c(-c2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

3(2H)-Isoquinolinone, 6,7-dimethoxy-1-phenyl- chemical structure, C17H15NO3, CAS 89721-03-9
3(2H)-Isoquinolinone, 6,7-dimethoxy-1-phenyl-
CAS 89721-03-9C17H15NO3
3(2H)-Isoquinolinone, 1-(2-chlorophenyl)- chemical structure, C15H10ClNO, CAS 89721-02-8
3(2H)-Isoquinolinone, 1-(2-chlorophenyl)-
CAS 89721-02-8C15H10ClNO
3(2H)-Isoquinolinone, 1-(4-chlorophenyl)- chemical structure, C15H10ClNO, CAS 89721-06-2
3(2H)-Isoquinolinone, 1-(4-chlorophenyl)-
CAS 89721-06-2C15H10ClNO
Ctk2D7424 chemical structure, C16H13NO, CAS 61561-63-5
Ctk2D7424
CAS 61561-63-5C16H13NO
1-Phenylisoquinolin-3(2H)-one chemical structure, C15H11NO, CAS 23832-72-6
1-Phenylisoquinolin-3(2H)-one
CAS 23832-72-6C15H11NO
1-(m-Tolyl)isoquinolin-3(2H)-one chemical structure, C16H13NO, CAS 61561-62-4
1-(m-Tolyl)isoquinolin-3(2H)-one
CAS 61561-62-4C16H13NO
1-(4-Ethylphenyl)isoquinolin-3(2H)-one chemical structure, C17H15NO, CAS 61561-64-6
1-(4-Ethylphenyl)isoquinolin-3(2H)-one
CAS 61561-64-6C17H15NO
1-(4-Isopropylphenyl)isoquinolin-3(2H)-one chemical structure, C18H17NO, CAS 61561-65-7
1-(4-Isopropylphenyl)isoquinolin-3(2H)-one
CAS 61561-65-7C18H17NO
1-(4-Methoxyphenyl)isoquinolin-3(2H)-one chemical structure, C16H13NO2, CAS 61561-66-8
1-(4-Methoxyphenyl)isoquinolin-3(2H)-one
CAS 61561-66-8C16H13NO2
5-Methyl-1-phenylisoquinolin-3(2H)-one chemical structure, C16H13NO, CAS 82255-68-3
5-Methyl-1-phenylisoquinolin-3(2H)-one
CAS 82255-68-3C16H13NO
N-(3-Oxo-1-phenyl-2,3-dihydroisoquinolin-4-yl)acetamide chemical structure, C17H14N2O2, CAS 112010-83-0
N-(3-Oxo-1-phenyl-2,3-dihydroisoquinolin-4-yl)acetamide
CAS 112010-83-0C17H14N2O2
N-(2-Methyl-3-oxo-1-phenyl-2,3-dihydroisoquinolin-4-yl)acetamide chemical structure, C18H16N2O2, CAS 112010-84-1
N-(2-Methyl-3-oxo-1-phenyl-2,3-dihydroisoquinolin-4-yl)acetamide
CAS 112010-84-1C18H16N2O2
6-Chloro-1-phenylisoquinolin-3(2H)-one chemical structure, C15H10ClNO, CAS 89721-05-1
6-Chloro-1-phenylisoquinolin-3(2H)-one
CAS 89721-05-1C15H10ClNO
2-(3-(Dimethylamino)propyl)-1-phenylisoquinolin-3(2H)-one chemical structure, C20H22N2O, CAS 89707-57-3
2-(3-(Dimethylamino)propyl)-1-phenylisoquinolin-3(2H)-one
CAS 89707-57-3C20H22N2O
1-(o-Tolyl)isoquinolin-3(2H)-one chemical structure, C16H13NO, CAS 89721-01-7
1-(o-Tolyl)isoquinolin-3(2H)-one
CAS 89721-01-7C16H13NO
6-Methyl-1-phenylisoquinolin-3(2H)-one chemical structure, C16H13NO, CAS 89721-04-0
6-Methyl-1-phenylisoquinolin-3(2H)-one
CAS 89721-04-0C16H13NO
2-[3-(Dimethylamino)propyl]-1-(2-methylphenyl)isoquinolin-3(2H)-one chemical structure, C21H24N2O, CAS 89721-13-1
2-[3-(Dimethylamino)propyl]-1-(2-methylphenyl)isoquinolin-3(2H)-one
CAS 89721-13-1C21H24N2O
2-Ethyl-1-phenyl-3(2H)-isoquinolinone chemical structure, C17H15NO, CAS 64262-24-4
2-Ethyl-1-phenyl-3(2H)-isoquinolinone
CAS 64262-24-4C17H15NO