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Murcko scaffold

1,2,3,4-Tetrahydro-1-phenylisoquinoline scaffold

218 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
218
With full pages
27
Scaffold SMILES

c1ccc(C2NCCc3ccccc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2,3,4-Tetrahydro-1-phenylisoquinoline page
Murcko scaffold c1ccc(C2NCCc3ccccc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 218 chemicals

1,2,3,4-Tetrahydro-1-(p-(isopropylsulfonyl)phenyl)-6,7-dimethoxy-isoquinoline chemical structure, C20H25NO4S, CAS 20884-90-6
1,2,3,4-Tetrahydro-1-(p-(isopropylsulfonyl)phenyl)-6,7-dimethoxy-isoquinoline
CAS 20884-90-6C20H25NO4S
Isoquinoline, 1,2,3,4-tetrahydro-1-(p-(isopropylsulfonyl)phenyl)-6,7-dimethoxy-2-methyl-, hydrochloride chemical structure, C21H28ClNO4S, CAS 20884-91-7
Isoquinoline, 1,2,3,4-tetrahydro-1-(p-(isopropylsulfonyl)phenyl)-6,7-dimethoxy-2-methyl-, hydrochloride
CAS 20884-91-7C21H28ClNO4S
6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-(p-(isopropylsulfonyl)phenyl)- chemical structure, C18H21NO4S, CAS 21140-78-3
6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-(p-(isopropylsulfonyl)phenyl)-
CAS 21140-78-3C18H21NO4S
N,N-Dimethyl-3-(1-phenyl-1,2,3,4-tetrahydroisoquinolin-1-yl)propan-1-amine chemical structure, C20H26N2, CAS 63937-68-8
N,N-Dimethyl-3-(1-phenyl-1,2,3,4-tetrahydroisoquinolin-1-yl)propan-1-amine
CAS 63937-68-8C20H26N2
1-(3,4-Dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline-4,6-diol--hydrogen chloride (1/1) chemical structure, C17H20ClNO4, CAS 72511-91-2
1-(3,4-Dimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline-4,6-diol--hydrogen chloride (1/1)
CAS 72511-91-2C17H20ClNO4
4,6-Isoquinolinediol, 1,2,3,4-tetrahydro-1-(4-methoxyphenyl)-, hydrochloride chemical structure, C16H18ClNO3, CAS 72512-00-6
4,6-Isoquinolinediol, 1,2,3,4-tetrahydro-1-(4-methoxyphenyl)-, hydrochloride
CAS 72512-00-6C16H18ClNO3
1-(3,4,5-Trimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline-4,6-diol--hydrogen chloride (1/1) chemical structure, C18H22ClNO5, CAS 72512-01-7
1-(3,4,5-Trimethoxyphenyl)-1,2,3,4-tetrahydroisoquinoline-4,6-diol--hydrogen chloride (1/1)
CAS 72512-01-7C18H22ClNO5
1,2,3,4-Tetrahydro-1-(3,4,5-trimethoxyphenyl)-4,6-isoquinolinediol chemical structure, C18H21NO5, CAS 93202-94-9
1,2,3,4-Tetrahydro-1-(3,4,5-trimethoxyphenyl)-4,6-isoquinolinediol
CAS 93202-94-9C18H21NO5
4,6-Isoquinolinediol, 1,2,3,4-tetrahydro-1-(4-hydroxy-3-methoxyphenyl)-, hexanedioate, hydrate (4:2:1) chemical structure, C22H27NO8, CAS 79677-09-1
4,6-Isoquinolinediol, 1,2,3,4-tetrahydro-1-(4-hydroxy-3-methoxyphenyl)-, hexanedioate, hydrate (4:2:1)
CAS 79677-09-1C22H27NO8
6-Isoquinolinol, 1,2,3,4-tetrahydro-1-(4-methoxyphenyl)-, hydrochloride chemical structure, C16H18ClNO2, CAS 93202-77-8
6-Isoquinolinol, 1,2,3,4-tetrahydro-1-(4-methoxyphenyl)-, hydrochloride
CAS 93202-77-8C16H18ClNO2
4,6-Isoquinolinediol, 1,2,3,4-tetrahydro-1-(2-hydroxyphenyl)- chemical structure, C15H15NO3, CAS 93203-01-1
4,6-Isoquinolinediol, 1,2,3,4-tetrahydro-1-(2-hydroxyphenyl)-
CAS 93203-01-1C15H15NO3
Hexanedioic acid--1-(4-hydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline-4,6-diol (1/1) chemical structure, C21H25NO7, CAS 93203-03-3
Hexanedioic acid--1-(4-hydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline-4,6-diol (1/1)
CAS 93203-03-3C21H25NO7
1-(2-Hydroxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline-4,6-diol--hydrogen chloride (1/1) chemical structure, C16H18ClNO3, CAS 93203-05-5
1-(2-Hydroxyphenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline-4,6-diol--hydrogen chloride (1/1)
CAS 93203-05-5C16H18ClNO3
4,6-Isoquinolinediol, 1,2,3,4-tetrahydro-1-(4-methoxyphenyl)-2-methyl-, hydrochloride, hydrate (2:2:1) chemical structure, C17H20ClNO3, CAS 93203-06-6
4,6-Isoquinolinediol, 1,2,3,4-tetrahydro-1-(4-methoxyphenyl)-2-methyl-, hydrochloride, hydrate (2:2:1)
CAS 93203-06-6C17H20ClNO3
6-Isoquinolinol, 1,2,3,4-tetrahydro-1-(2-hydroxyphenyl)-, hydrochloride chemical structure, C15H16ClNO2, CAS 93203-08-8
6-Isoquinolinol, 1,2,3,4-tetrahydro-1-(2-hydroxyphenyl)-, hydrochloride
CAS 93203-08-8C15H16ClNO2
4-Chloro-n-methyl-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)aniline chemical structure, C16H17ClN2, CAS 23495-28-5
4-Chloro-n-methyl-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)aniline
CAS 23495-28-5C16H17ClN2
1,2,3,4-Tetrahydro-1-phenylisoquinoline chemical structure, C15H15N, CAS 22990-19-8
1,2,3,4-Tetrahydro-1-phenylisoquinoline
CAS 22990-19-8C15H15N
1-Methyl-1-phenyl-1,2,3,4-tetrahydroisoquinoline chemical structure, C16H18ClN, CAS 126114-66-7
1-Methyl-1-phenyl-1,2,3,4-tetrahydroisoquinoline
CAS 126114-66-7C16H18ClN
1,2,3,4-Tetrahydro-1-methyl-1-phenylisoquinoline chemical structure, C16H17N, CAS 136226-78-3
1,2,3,4-Tetrahydro-1-methyl-1-phenylisoquinoline
CAS 136226-78-3C16H17N
6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline chemical structure, C17H19NO2, CAS 4118-36-9
6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline
CAS 4118-36-9C17H19NO2
1-Phenyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol chemical structure, C15H15NO2, CAS 17579-12-3
1-Phenyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol
CAS 17579-12-3C15H15NO2
Isoquinoline, 1,2,3,4-tetrahydro-2-acetyl-6,7-dimethoxy-1-(p-(isopropylsulfonyl)phenyl)- chemical structure, C22H27NO5S, CAS 20884-92-8
Isoquinoline, 1,2,3,4-tetrahydro-2-acetyl-6,7-dimethoxy-1-(p-(isopropylsulfonyl)phenyl)-
CAS 20884-92-8C22H27NO5S
1-Phenyl-3,4-dihydroisoquinoline-2(1H)-carboxamide chemical structure, C16H16N2O, CAS 42063-87-6
1-Phenyl-3,4-dihydroisoquinoline-2(1H)-carboxamide
CAS 42063-87-6C16H16N2O
1,2,3,4-Tetrahydro-2-methyl-1-phenylisoquinoline chemical structure, C16H17N, CAS 7149-64-6
1,2,3,4-Tetrahydro-2-methyl-1-phenylisoquinoline
CAS 7149-64-6C16H17N