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Murcko scaffold

4-(Morpholinosulfonyl)-N-(4-phenylthiazol-2-yl)benzamide scaffold

24 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
29
Chemicals
24
With full pages
4
Scaffold SMILES

O=C(Nc1nc(-c2ccccc2)cs1)c1ccc(S(=O)(=O)N2CCOCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Morpholinosulfonyl)-N-(4-phenylthiazol-2-yl)benzamide page
Murcko scaffold O=C(Nc1nc(-c2ccccc2)cs1)c1ccc(S(=O)(=O)N2CCOCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

4-(Morpholinosulfonyl)-N-(4-(p-tolyl)thiazol-2-yl)benzamide chemical structure, C21H21N3O4S2, CAS 313537-98-3
4-(Morpholinosulfonyl)-N-(4-(p-tolyl)thiazol-2-yl)benzamide
CAS 313537-98-3C21H21N3O4S2
4-(Morpholinosulfonyl)-N-(4-phenylthiazol-2-yl)benzamide chemical structure, C20H19N3O4S2, CAS 313520-86-4
4-(Morpholinosulfonyl)-N-(4-phenylthiazol-2-yl)benzamide
CAS 313520-86-4C20H19N3O4S2
N-(4-(3,4-Dichlorophenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide chemical structure, C20H17Cl2N3O4S2, CAS 313661-87-9
N-(4-(3,4-Dichlorophenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide
CAS 313661-87-9C20H17Cl2N3O4S2
N-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-4-morpholin-4-ylsulfonylbenzamide chemical structure, C20H18FN3O4S2, CAS 313531-48-5
N-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-4-morpholin-4-ylsulfonylbenzamide
CAS 313531-48-5C20H18FN3O4S2
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-4-morpholin-4-ylsulfonylbenzamide chemical structure, C20H18ClN3O4S2, CAS 324774-36-9
N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-4-morpholin-4-ylsulfonylbenzamide
CAS 324774-36-9C20H18ClN3O4S2
N-(4-(4-Ethylphenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide chemical structure, C22H23N3O4S2, CAS 313531-52-1
N-(4-(4-Ethylphenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide
CAS 313531-52-1C22H23N3O4S2
N-[4-(2-Methoxyphenyl)-1,3-thiazol-2-yl]-4-(morpholine-4-sulfonyl)benzamide chemical structure, C21H21N3O5S2, CAS 312755-13-8
N-[4-(2-Methoxyphenyl)-1,3-thiazol-2-yl]-4-(morpholine-4-sulfonyl)benzamide
CAS 312755-13-8C21H21N3O5S2
4-(Morpholinosulfonyl)-N-(4-(3-nitrophenyl)thiazol-2-yl)benzamide chemical structure, C20H18N4O6S2, CAS 326907-69-1
4-(Morpholinosulfonyl)-N-(4-(3-nitrophenyl)thiazol-2-yl)benzamide
CAS 326907-69-1C20H18N4O6S2
N-(4-(4-Cyanophenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide chemical structure, C21H18N4O4S2, CAS 300568-28-9
N-(4-(4-Cyanophenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide
CAS 300568-28-9C21H18N4O4S2
N-[4-(4-tert-Butylphenyl)-1,3-thiazol-2-yl]-4-(morpholine-4-sulfonyl)benzamide chemical structure, C24H27N3O4S2, CAS 380453-39-4
N-[4-(4-tert-Butylphenyl)-1,3-thiazol-2-yl]-4-(morpholine-4-sulfonyl)benzamide
CAS 380453-39-4C24H27N3O4S2
N-(4-(4-Bromophenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide chemical structure, C20H18BrN3O4S2, CAS 325978-78-7
N-(4-(4-Bromophenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide
CAS 325978-78-7C20H18BrN3O4S2
N-(4-Mesitylthiazol-2-yl)-4-(morpholinosulfonyl)benzamide chemical structure, C23H25N3O4S2, CAS 325978-79-8
N-(4-Mesitylthiazol-2-yl)-4-(morpholinosulfonyl)benzamide
CAS 325978-79-8C23H25N3O4S2
N-(4-(2,4-Dimethoxyphenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide chemical structure, C22H23N3O6S2, CAS 361481-75-6
N-(4-(2,4-Dimethoxyphenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide
CAS 361481-75-6C22H23N3O6S2
N-(4-(2,4-Dimethylphenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide chemical structure, C22H23N3O4S2, CAS 312755-10-5
N-(4-(2,4-Dimethylphenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide
CAS 312755-10-5C22H23N3O4S2
N-(4-(4-Isopropylphenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide chemical structure, C23H25N3O4S2, CAS 313364-86-2
N-(4-(4-Isopropylphenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide
CAS 313364-86-2C23H25N3O4S2
N-(4-(3,4-Dimethylphenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide chemical structure, C22H23N3O4S2, CAS 313261-60-8
N-(4-(3,4-Dimethylphenyl)thiazol-2-yl)-4-(morpholinosulfonyl)benzamide
CAS 313261-60-8C22H23N3O4S2
Methyl 4-[2-[(4-morpholin-4-ylsulfonylbenzoyl)amino]-1,3-thiazol-4-yl]benzoate chemical structure, C22H21N3O6S2, CAS 361173-42-4
Methyl 4-[2-[(4-morpholin-4-ylsulfonylbenzoyl)amino]-1,3-thiazol-4-yl]benzoate
CAS 361173-42-4C22H21N3O6S2
4-((2,6-Dimethylmorpholino)sulfonyl)-N-(4-(4-ethoxyphenyl)thiazol-2-yl)benzamide chemical structure, C24H27N3O5S2, CAS 361481-61-0
4-((2,6-Dimethylmorpholino)sulfonyl)-N-(4-(4-ethoxyphenyl)thiazol-2-yl)benzamide
CAS 361481-61-0C24H27N3O5S2
Ethyl 2-(4-(morpholinosulfonyl)benzamido)-4-phenylthiazole-5-carboxylate chemical structure, C23H23N3O6S2, CAS 305852-29-3
Ethyl 2-(4-(morpholinosulfonyl)benzamido)-4-phenylthiazole-5-carboxylate
CAS 305852-29-3C23H23N3O6S2
4-((2,6-Dimethylmorpholino)sulfonyl)-N-(4-(3-nitrophenyl)thiazol-2-yl)benzamide chemical structure, C22H22N4O6S2, CAS 314275-58-6
4-((2,6-Dimethylmorpholino)sulfonyl)-N-(4-(3-nitrophenyl)thiazol-2-yl)benzamide
CAS 314275-58-6C22H22N4O6S2
N-(4-(2,4-Dimethoxyphenyl)thiazol-2-yl)-4-((2,6-dimethylmorpholino)sulfonyl)benzamide chemical structure, C24H27N3O6S2, CAS 361171-08-6
N-(4-(2,4-Dimethoxyphenyl)thiazol-2-yl)-4-((2,6-dimethylmorpholino)sulfonyl)benzamide
CAS 361171-08-6C24H27N3O6S2
4-(Morpholinosulfonyl)-N-(4-(4-propoxyphenyl)thiazol-2-yl)benzamide chemical structure, C23H25N3O5S2, CAS 325979-60-0
4-(Morpholinosulfonyl)-N-(4-(4-propoxyphenyl)thiazol-2-yl)benzamide
CAS 325979-60-0C23H25N3O5S2
N-(5-Acetyl-4-phenylthiazol-2-yl)-4-((2,6-dimethylmorpholino)sulfonyl)benzamide chemical structure, C24H25N3O5S2, CAS 681237-39-8
N-(5-Acetyl-4-phenylthiazol-2-yl)-4-((2,6-dimethylmorpholino)sulfonyl)benzamide
CAS 681237-39-8C24H25N3O5S2
Agn-PC-0lozvf chemical structure, C22H23N3O4S2, CAS 5634-87-7
Agn-PC-0lozvf
CAS 5634-87-7C22H23N3O4S2