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Murcko scaffold

2-Hydroxyimidazole scaffold

221 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
221
With full pages
25
Scaffold SMILES

O=c1[nH]cc[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 2-Hydroxyimidazole page
Murcko scaffold O=c1[nH]cc[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 221 chemicals

2-Hydroxyimidazole chemical structure, C3H4N2O, CAS 5918-93-4
2-Hydroxyimidazole
CAS 5918-93-4C3H4N2O
1-Butyl-5-methyl-2-imidazolone chemical structure, C8H14N2O, CAS 14059-05-3
1-Butyl-5-methyl-2-imidazolone
CAS 14059-05-3C8H14N2O
N-(2-Methylpropyl)-2-oxo-3H-imidazole-1-carboxamide chemical structure, C8H13N3O2, CAS 67292-92-6
N-(2-Methylpropyl)-2-oxo-3H-imidazole-1-carboxamide
CAS 67292-92-6C8H13N3O2
1,3-Dihydro-4-methyl-2H-imidazol-2-one chemical structure, C4H6N2O, CAS 1192-34-3
1,3-Dihydro-4-methyl-2H-imidazol-2-one
CAS 1192-34-3C4H6N2O
6-(5-Methyl-2-oxo-2,3-dihydro-1H-imidazol-4-yl)-6-oxo-hexanoic acid chemical structure, C10H14N2O4, CAS 19920-34-4
6-(5-Methyl-2-oxo-2,3-dihydro-1H-imidazol-4-yl)-6-oxo-hexanoic acid
CAS 19920-34-4C10H14N2O4
Methyl 2,3-dihydro-2-oxo-1H-imidazole-4-carboxylate chemical structure, C5H6N2O3, CAS 20901-53-5
Methyl 2,3-dihydro-2-oxo-1H-imidazole-4-carboxylate
CAS 20901-53-5C5H6N2O3
2-Oxohistidine chemical structure, C6H9N3O3, CAS 151436-49-6
2-Oxohistidine
CAS 151436-49-6C6H9N3O3
2-(2-Oxo-4-imidazolin-4-yl)ethylamine chemical structure, C5H9N3O, CAS 1004-21-3
2-(2-Oxo-4-imidazolin-4-yl)ethylamine
CAS 1004-21-3C5H9N3O
1-Methylhydantoin 5-oxime chemical structure, C4H5N3O3, CAS 34356-74-6
1-Methylhydantoin 5-oxime
CAS 34356-74-6C4H5N3O3
Ethyl 5-methyl-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate chemical structure, C7H10N2O3, CAS 82831-19-4
Ethyl 5-methyl-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate
CAS 82831-19-4C7H10N2O3
Methyl 5-(2-methoxy-2-oxoethyl)-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate chemical structure, C8H10N2O5, CAS 92203-27-5
Methyl 5-(2-methoxy-2-oxoethyl)-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate
CAS 92203-27-5C8H10N2O5
Methyl 5-(3-methoxy-3-oxopropyl)-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate chemical structure, C9H12N2O5, CAS 6333-19-3
Methyl 5-(3-methoxy-3-oxopropyl)-2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate
CAS 6333-19-3C9H12N2O5
5-Amino-2-oxo-2,3-dihydro-1H-imidazole-4-carboxamide chemical structure, C4H6N4O2, CAS 52868-65-2
5-Amino-2-oxo-2,3-dihydro-1H-imidazole-4-carboxamide
CAS 52868-65-2C4H6N4O2
2H-Imidazol-2-one, 1,3-dihydro-1,3-bis(trimethylsilyl)- chemical structure, C9H20N2OSi2, CAS 61233-69-0
2H-Imidazol-2-one, 1,3-dihydro-1,3-bis(trimethylsilyl)-
CAS 61233-69-0C9H20N2OSi2
1-Methyl-2,3-dihydro-1H-imidazol-2-one chemical structure, C4H6N2O, CAS 39799-77-4
1-Methyl-2,3-dihydro-1H-imidazol-2-one
CAS 39799-77-4C4H6N2O
2-Oxo-2,3-dihydro-1H-imidazole-4-carbonitrile chemical structure, C4H3N3O, CAS 159263-03-3
2-Oxo-2,3-dihydro-1H-imidazole-4-carbonitrile
CAS 159263-03-3C4H3N3O
4-Acetyl-5-methyl-1,3-dihydro-2H-imidazol-2-one chemical structure, C6H8N2O2, CAS 53064-61-2
4-Acetyl-5-methyl-1,3-dihydro-2H-imidazol-2-one
CAS 53064-61-2C6H8N2O2
Ethyl 2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate chemical structure, C6H8N2O3, CAS 71123-14-3
Ethyl 2-oxo-2,3-dihydro-1H-imidazole-4-carboxylate
CAS 71123-14-3C6H8N2O3
2-Oxo-2,3-dihydro-1H-imidazole-4-carboxylic acid chemical structure, C4H4N2O3, CAS 39828-47-2
2-Oxo-2,3-dihydro-1H-imidazole-4-carboxylic acid
CAS 39828-47-2C4H4N2O3
Ethyl 2,3-dihydro-5-methyl-epsilon-2-dioxo-1H-imidazole-4-hexanoate chemical structure, C12H18N2O4, CAS 39215-52-6
Ethyl 2,3-dihydro-5-methyl-epsilon-2-dioxo-1H-imidazole-4-hexanoate
CAS 39215-52-6C12H18N2O4
2-Oxo-2,3-dihydro-1H-imidazole-4-carbaldehyde chemical structure, C4H4N2O2, CAS 72864-28-9
2-Oxo-2,3-dihydro-1H-imidazole-4-carbaldehyde
CAS 72864-28-9C4H4N2O2
Isobutyl 2,3-dihydro-2-oxo-1H-imidazole-4-carboxylate chemical structure, C8H12N2O3, CAS 93805-09-5
Isobutyl 2,3-dihydro-2-oxo-1H-imidazole-4-carboxylate
CAS 93805-09-5C8H12N2O3
2H-Imidazol-2-one, 1-(1,1-dimethylethyl)-1,3-dihydro- chemical structure, C7H12N2O, CAS 92075-17-7
2H-Imidazol-2-one, 1-(1,1-dimethylethyl)-1,3-dihydro-
CAS 92075-17-7C7H12N2O
Ethyl 5-bromo-6-(5-methyl-2-oxo-2,3-dihydro-1H-imidazol-4-yl)-6-oxohexanoate chemical structure, C12H17BrN2O4, CAS 91459-21-1
Ethyl 5-bromo-6-(5-methyl-2-oxo-2,3-dihydro-1H-imidazol-4-yl)-6-oxohexanoate
CAS 91459-21-1C12H17BrN2O4