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Murcko scaffold

Ring system with 2 rings and 12 atoms

31 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
31
With full pages
3
Scaffold SMILES

c1ccc(Cc2ncsn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cc2ncsn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

3-Benzyl-1,2,4-thiadiazol-5-amine chemical structure, C9H9N3S, CAS 17467-27-5
3-Benzyl-1,2,4-thiadiazol-5-amine
CAS 17467-27-5C9H9N3S
3-(4-Nitrobenzyl)-1,2,4-thiadiazol-5-amine chemical structure, C9H8N4O2S, CAS 440113-24-6
3-(4-Nitrobenzyl)-1,2,4-thiadiazol-5-amine
CAS 440113-24-6C9H8N4O2S
3-Benzyl-5-chloro-1,2,4-thiadiazole chemical structure, C9H7ClN2S, CAS 99067-57-9
3-Benzyl-5-chloro-1,2,4-thiadiazole
CAS 99067-57-9C9H7ClN2S
5-Chloro-3-(3-methyl-benzyl)-[1,2,4]thiadiazole chemical structure, C10H9ClN2S, CAS 525574-77-0
5-Chloro-3-(3-methyl-benzyl)-[1,2,4]thiadiazole
CAS 525574-77-0C10H9ClN2S
5-Chloro-3-{[3-(trifluoromethyl)phenyl]methyl}-1,2,4-thiadiazole chemical structure, C10H6ClF3N2S, CAS 1221346-00-4
5-Chloro-3-{[3-(trifluoromethyl)phenyl]methyl}-1,2,4-thiadiazole
CAS 1221346-00-4C10H6ClF3N2S
3-((4-Chlorophenyl)methyl)-1,2,4-thiadiazol-5-amine chemical structure, C9H8ClN3S, CAS 1082508-64-2
3-((4-Chlorophenyl)methyl)-1,2,4-thiadiazol-5-amine
CAS 1082508-64-2C9H8ClN3S
5-Chloro-3-[(2-chlorophenyl)methyl]-1,2,4-thiadiazole chemical structure, C9H6Cl2N2S, CAS 90418-15-8
5-Chloro-3-[(2-chlorophenyl)methyl]-1,2,4-thiadiazole
CAS 90418-15-8C9H6Cl2N2S
5-Chloro-3-(3-chloro-benzyl)-[1,2,4]thiadiazole chemical structure, C9H6Cl2N2S, CAS 1221345-99-8
5-Chloro-3-(3-chloro-benzyl)-[1,2,4]thiadiazole
CAS 1221345-99-8C9H6Cl2N2S
3-[(4-Bromophenyl)methyl]-5-chloro-1,2,4-thiadiazole chemical structure, C9H6BrClN2S, CAS 1221342-57-9
3-[(4-Bromophenyl)methyl]-5-chloro-1,2,4-thiadiazole
CAS 1221342-57-9C9H6BrClN2S
5-Chloro-3-[(2,4-dichlorophenyl)methyl]-1,2,4-thiadiazole chemical structure, C9H5Cl3N2S, CAS 90483-74-2
5-Chloro-3-[(2,4-dichlorophenyl)methyl]-1,2,4-thiadiazole
CAS 90483-74-2C9H5Cl3N2S
5-Chloro-3-[(3,4-dimethoxyphenyl)methyl]-1,2,4-thiadiazole chemical structure, C11H11ClN2O2S, CAS 1221342-59-1
5-Chloro-3-[(3,4-dimethoxyphenyl)methyl]-1,2,4-thiadiazole
CAS 1221342-59-1C11H11ClN2O2S
5-Chloro-3-[(2-methylphenyl)methyl]-1,2,4-thiadiazole chemical structure, C10H9ClN2S, CAS 1029718-70-4
5-Chloro-3-[(2-methylphenyl)methyl]-1,2,4-thiadiazole
CAS 1029718-70-4C10H9ClN2S
5-Chloro-3-[(3-fluorophenyl)methyl]-1,2,4-thiadiazole chemical structure, C9H6ClFN2S, CAS 1029718-68-0
5-Chloro-3-[(3-fluorophenyl)methyl]-1,2,4-thiadiazole
CAS 1029718-68-0C9H6ClFN2S
5-Chloro-3-[(4-methylphenyl)methyl]-1,2,4-thiadiazole chemical structure, C10H9ClN2S, CAS 946418-97-9
5-Chloro-3-[(4-methylphenyl)methyl]-1,2,4-thiadiazole
CAS 946418-97-9C10H9ClN2S
5-Chloro-3-[(2-methoxyphenyl)methyl]-1,2,4-thiadiazole chemical structure, C10H9ClN2OS, CAS 1029718-71-5
5-Chloro-3-[(2-methoxyphenyl)methyl]-1,2,4-thiadiazole
CAS 1029718-71-5C10H9ClN2OS
5-Chloro-3-[(2-fluorophenyl)methyl]-1,2,4-thiadiazole chemical structure, C9H6ClFN2S, CAS 1029718-69-1
5-Chloro-3-[(2-fluorophenyl)methyl]-1,2,4-thiadiazole
CAS 1029718-69-1C9H6ClFN2S
5-Chloro-3-(4-fluorobenzyl)-1,2,4-thiadiazole chemical structure, C9H6ClFN2S, CAS 946418-98-0
5-Chloro-3-(4-fluorobenzyl)-1,2,4-thiadiazole
CAS 946418-98-0C9H6ClFN2S
5-Chloro-3-[(4-nitrophenyl)methyl]-1,2,4-thiadiazole chemical structure, C9H6ClN3O2S, CAS 1221342-62-6
5-Chloro-3-[(4-nitrophenyl)methyl]-1,2,4-thiadiazole
CAS 1221342-62-6C9H6ClN3O2S
5-Chloro-3-[(3-methoxyphenyl)methyl]-1,2,4-thiadiazole chemical structure, C10H9ClN2OS, CAS 946418-99-1
5-Chloro-3-[(3-methoxyphenyl)methyl]-1,2,4-thiadiazole
CAS 946418-99-1C10H9ClN2OS
5-Chloro-3-[(4-methoxyphenyl)methyl]-1,2,4-thiadiazole chemical structure, C10H9ClN2OS, CAS 1029718-72-6
5-Chloro-3-[(4-methoxyphenyl)methyl]-1,2,4-thiadiazole
CAS 1029718-72-6C10H9ClN2OS
5-Chloro-3-[(3,4-dichlorophenyl)methyl]-1,2,4-thiadiazole chemical structure, C9H5Cl3N2S, CAS 1221341-22-5
5-Chloro-3-[(3,4-dichlorophenyl)methyl]-1,2,4-thiadiazole
CAS 1221341-22-5C9H5Cl3N2S
5-Chloro-3-[(4-chlorophenyl)methyl]-1,2,4-thiadiazole chemical structure, C9H6Cl2N2S, CAS 90418-16-9
5-Chloro-3-[(4-chlorophenyl)methyl]-1,2,4-thiadiazole
CAS 90418-16-9C9H6Cl2N2S
5-Chloro-3-[(2,6-dichlorophenyl)methyl]-1,2,4-thiadiazole chemical structure, C9H5Cl3N2S, CAS 1221341-60-1
5-Chloro-3-[(2,6-dichlorophenyl)methyl]-1,2,4-thiadiazole
CAS 1221341-60-1C9H5Cl3N2S
5-Chloro-3-[(4-fluoro-3-methylphenyl)methyl]-1,2,4-thiadiazole chemical structure, C10H8ClFN2S, CAS 1029718-73-7
5-Chloro-3-[(4-fluoro-3-methylphenyl)methyl]-1,2,4-thiadiazole
CAS 1029718-73-7C10H8ClFN2S