Murcko scaffold
1-(Phenylsulfonyl)pyrrolidine scaffold
843 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 843
- With full pages
- 146
Scaffold SMILES
O=S(=O)(c1ccccc1)N1CCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 843 chemicals
Pyrrolidine, 2,5-dimethyl-1-((4-methylphenyl)sulfonyl)-, cis-
CAS 81330-01-0C13H19NO2S
Pyrrolidine, 1-((4-methylphenyl)sulfonyl)-2,5-dipropyl-, trans-
CAS 123993-96-4C17H27NO2S
Pyrrolidine, 2,5-dimethyl-1-((4-methylphenyl)sulfonyl)-, trans-
CAS 123993-97-5C13H19NO2S
Pyrrolidine, 2-butyl-5-heptyl-1-((4-methylphenyl)sulfonyl)-, trans-
CAS 123993-98-6C22H37NO2S
Pyrrolidine, 2-butyl-1-((4-methylphenyl)sulfonyl)-5-propyl-, trans-
CAS 123993-99-7C18H29NO2S
Pyrrolidine, 1-((4-methylphenyl)sulfonyl)-2,5-dipropyl-, cis-
CAS 123994-00-3C17H27NO2S
Pyrrolidine, 2-butyl-5-heptyl-1-((4-methylphenyl)sulfonyl)-, cis-
CAS 123994-01-4C22H37NO2S
Pyrrolidine, 2,5-dibutyl-1-((4-methylphenyl)sulfonyl)-, cis-
CAS 123994-02-5C19H31NO2S
Phosphorothioic acid, O,O-dimethyl O-(p-(pyrrolidinylsulfonyl)phenyl) ester
CAS 3078-93-1C12H18NO5PS2
1-(Phenylsulfonyl)pyrrolidine
CAS 5033-22-7C10H13NO2S
1-((3-Nitrophenyl)sulfonyl)pyrrolidine
CAS 91619-30-6C10H12N2O4S
![1-[(4-Methylphenyl)sulfonyl]pyrrolidine chemical structure, C11H15NO2S, CAS 6435-78-5](/s/KDWPQSBXEHQMSD-UHFFFAOYSA-N.svg)
1-[(4-Methylphenyl)sulfonyl]pyrrolidine
CAS 6435-78-5C11H15NO2S
![1-[(4-Methoxyphenyl)sulfonyl]pyrrolidine chemical structure, C11H15NO3S, CAS 335215-12-8](/s/LBMXZZFSJLBRGH-UHFFFAOYSA-N.svg)
1-[(4-Methoxyphenyl)sulfonyl]pyrrolidine
CAS 335215-12-8C11H15NO3S
![4-Hydroxy-1-[(4-methylphenyl)sulfonyl]-2-pyrrolidinecarboxylic acid chemical structure, C12H15NO5S, CAS 16257-64-0](/s/UAFPTDLCLKLJKA-UHFFFAOYSA-N.svg)
4-Hydroxy-1-[(4-methylphenyl)sulfonyl]-2-pyrrolidinecarboxylic acid
CAS 16257-64-0C12H15NO5S
RefChem:381296
CAS 91645-35-1C12H17NO3S
![L-Proline, 4-hydroxy-1-[(4-methylphenyl)sulfonyl]-, (4R)- chemical structure, C12H15NO5S, CAS 20275-18-7](/s/UAFPTDLCLKLJKA-KOLCDFICSA-N.svg)
L-Proline, 4-hydroxy-1-[(4-methylphenyl)sulfonyl]-, (4R)-
CAS 20275-18-7C12H15NO5S
Tosyl-D-proline
CAS 110771-95-4C12H15NO4S
4-(Pyrrolidine-1-sulfonyl)aniline
CAS 88327-91-7C10H14N2O2S
1-(Phenylsulfonyl)pyrrolidine-2-carbohydrazide
CAS 1032190-58-1C11H15N3O3S
1-(Toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid
CAS 370883-85-5C12H15NO4S
![1-[(3,4-Dimethoxyphenyl)sulfonyl]proline chemical structure, C13H17NO6S, CAS 367928-20-9](/s/KXBVANCVBWUHCU-UHFFFAOYSA-N.svg)
1-[(3,4-Dimethoxyphenyl)sulfonyl]proline
CAS 367928-20-9C13H17NO6S
![N-{2-[4-(Pyrrolidin-1-ylsulfonyl)phenyl]ethyl}acetamide chemical structure, C14H20N2O3S, CAS 345993-13-7](/s/GNCXFROBWRZEJR-UHFFFAOYSA-N.svg)
N-{2-[4-(Pyrrolidin-1-ylsulfonyl)phenyl]ethyl}acetamide
CAS 345993-13-7C14H20N2O3S
Ethyl 1-(phenylsulfonyl)prolinate
CAS 1094619-25-6C13H17NO4S
Methyl 1-(phenylsulfonyl)prolinate
CAS 288154-77-8C12H15NO4S
- 1-(4-Methylphenyl)sulfonylpyrrolidine-2-carboxamide1008481-04-6C12H16N2O3S
- Methyl 1-(4-methylphenyl)sulfonylpyrrolidine-2-carboxylate388615-74-5C13H17NO4S
- 3 suppliers1-(4-Fluorobenzenesulfonyl)pyrrolidine-2-carboxylic acid251096-96-5C11H12FNO4S
- Methyl 1-[(4-ethylphenyl)sulfonyl]prolinate484049-67-4C14H19NO4S
- Methyl 4-hydroxy-1-tosylpyrrolidine-2-carboxylate16257-57-1C13H17NO5S
- 4-Hydroxy-1-(4-nitrobenzenesulfonyl)pyrrolidine-2-carboxylic acid91088-77-6C11H12N2O7S
- 1-[(2,5-Dichlorophenyl)sulfonyl]proline298687-02-2C11H11Cl2NO4S
- Ethyl 4-oxo-4-(4-pyrrolidin-1-ylsulfonylanilino)butanoate356550-82-8C16H22N2O5S
- (2S)-1-{[4-(tert-Butyl)phenyl]sulfonyl}pyrrolidine-2-carboxylic acid286455-85-4C15H21NO4S
- 1 suppliers(2S)-1-(4-Fluorobenzenesulfonyl)pyrrolidine-2-carboxylic acid97801-56-4C11H12FNO4S
- (2R)-1-(4-Fluorobenzenesulfonyl)pyrrolidine-2-carboxylic acid910481-87-7C11H12FNO4S
- (2S)-1-(4-Methylbenzenesulfonyl)pyrrolidine-2-carboxylic acid51077-01-1C12H15NO4S
- 2,2-Dichloro-N-(4-pyrrolidin-1-ylsulfonylphenyl)acetamide590398-76-8C12H14Cl2N2O3S
- 3,3-Dimethyl-N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]butanamide510736-60-4C16H24N2O3S
- 3-Methyl-N-(4-pyrrolidin-1-ylsulfonylphenyl)butanamide521294-97-3C15H22N2O3S
- 2,2-Dimethyl-N-(4-pyrrolidin-1-ylsulfonylphenyl)propanamide510737-16-3C15H22N2O3S
- 1-(3-Chloro-4-fluorophenyl)sulfonylpyrrolidine613657-54-8C10H11ClFNO2S
- 1-[4-Chloro-3-(trifluoromethyl)phenyl]sulfonylpyrrolidine612043-65-9C11H11ClF3NO2S
- 1-(2,5-Dichloro-4-methoxyphenyl)sulfonylpyrrolidine667892-60-6C11H13Cl2NO3S
- 1-(4-Fluoro-3-methylphenyl)sulfonylpyrrolidine691381-07-4C11H14FNO2S
- 1-(5-Bromo-2-methoxyphenylsulfonyl)pyrrolidine691381-10-9C11H14BrNO3S
- 4-Bromo-2-(1-pyrrolidinylsulfonyl)phenyl ethyl ether691381-11-0C12H16BrNO3S
- 1-(2,3,4-Trichlorobenzenesulfonyl)pyrrolidine691381-12-1C10H10Cl3NO2S
- 1-(2-Methoxy-4-methylphenyl)sulfonylpyrrolidine691381-26-7C12H17NO3S
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cn2cccn2)cc1271 chemicals
c1ccc(CN2CCCC2)cc1172 chemicals
c1ccc(Cn2ccnc2)cc1107 chemicals![Scaffold c1ccc(N=c2[nH]ccs2)cc1](/scaffold/OGVGQYZRJXSMGC-UHFFFAOYSA-N/structure.svg)
c1ccc(N=c2[nH]ccs2)cc198 chemicals
O=C1NC(=S)SC1=Cc1ccccc186 chemicals
O=C(c1ccccc1)N1CCCC186 chemicals
O=S(=O)(c1ccccc1)n1ccnc184 chemicals![Scaffold O=C(c1ccccc1)c1cc[nH]c1](/scaffold/DSNSKSWTLGZGAN-UHFFFAOYSA-N/structure.svg)
O=C(c1ccccc1)c1cc[nH]c177 chemicals
c1ccc(Cn2ccnn2)cc177 chemicals
c1ccc(Cc2cncs2)cc175 chemicals
c1ccc(Cn2cccc2)cc163 chemicals
O=S(=O)(c1ccccc1)n1cccn160 chemicals