Murcko scaffold
Benzyl cyclopropylcarbamate scaffold
148 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 148
- With full pages
- 2
Scaffold SMILES
O=C(NC1CC1)OCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 148 chemicals
![[1-(N-Hydroxycarbamimidoyl)-cyclopropyl]-carbamic acid benzyl ester chemical structure, C12H15N3O3, CAS 940868-34-8](/s/BEQYTYPAVVHIMQ-UHFFFAOYSA-N.svg)
[1-(N-Hydroxycarbamimidoyl)-cyclopropyl]-carbamic acid benzyl ester
CAS 940868-34-8C12H15N3O3
4-Methoxybenzyl (1-(iodomethyl)cyclopropyl)carbamate
CAS 1620284-35-6C13H16INO3
![N-[1-[[(Methylsulfonyl)oxy]methyl]cyclopropyl]carbamic acid (4-methoxyphenyl)methyl ester chemical structure, C14H19NO6S, CAS 1620284-34-5](/s/XSPCCYHRSNRDEY-UHFFFAOYSA-N.svg)
N-[1-[[(Methylsulfonyl)oxy]methyl]cyclopropyl]carbamic acid (4-methoxyphenyl)methyl ester
CAS 1620284-34-5C14H19NO6S
![(4-Methoxyphenyl)methyl N-[1-(hydroxymethyl)cyclopropyl]carbamate chemical structure, C13H17NO4, CAS 1620284-33-4](/s/ISTNEBAOIRVJHP-UHFFFAOYSA-N.svg)
(4-Methoxyphenyl)methyl N-[1-(hydroxymethyl)cyclopropyl]carbamate
CAS 1620284-33-4C13H17NO4
Ethyl 1-((((4-methoxybenzyl)oxy)carbonyl)amino)cyclopropane-1-carboxylate
CAS 1620284-32-3C15H19NO5
![(R,E)-{1-[(2-Methylpropane-2-sulfinylimino)-methyl]-cyclopropyl}-carbamic acid benzyl ester chemical structure, C16H22N2O3S, CAS 1439908-49-2](/s/GIEMVIIGDOTPMP-UHFFFAOYSA-N.svg)
(R,E)-{1-[(2-Methylpropane-2-sulfinylimino)-methyl]-cyclopropyl}-carbamic acid benzyl ester
CAS 1439908-49-2C16H22N2O3S
![rac-(1R,2R)-2-{[(Benzyloxy)carbonyl]amino}cyclopropane-1-carboxylicacid chemical structure, C12H13NO4, CAS 1903448-54-3](/s/YVDRLUVVYKRYEB-NXEZZACHSA-N.svg)
rac-(1R,2R)-2-{[(Benzyloxy)carbonyl]amino}cyclopropane-1-carboxylicacid
CAS 1903448-54-3C12H13NO4
![rac-(1R,2S)-2-{[(Benzyloxy)carbonyl]amino}cyclopropane-1-carboxylic acid chemical structure, C12H13NO4, CAS 1903302-86-2](/s/YVDRLUVVYKRYEB-ZJUUUORDSA-N.svg)
rac-(1R,2S)-2-{[(Benzyloxy)carbonyl]amino}cyclopropane-1-carboxylic acid
CAS 1903302-86-2C12H13NO4
![Benzyl N-{1-[(chlorosulfonyl)methyl]cyclopropyl}carbamate chemical structure, C12H14ClNO4S, CAS 1784288-65-8](/s/TXVWUOSLBQJVGE-UHFFFAOYSA-N.svg)
Benzyl N-{1-[(chlorosulfonyl)methyl]cyclopropyl}carbamate
CAS 1784288-65-8C12H14ClNO4S
![Benzyl N-{1-[2-(chlorosulfonyl)ethyl]cyclopropyl}carbamate chemical structure, C13H16ClNO4S, CAS 1780294-77-0](/s/UQOXHIQZIBVZAL-UHFFFAOYSA-N.svg)
Benzyl N-{1-[2-(chlorosulfonyl)ethyl]cyclopropyl}carbamate
CAS 1780294-77-0C13H16ClNO4S
Benzyl 1-(azidomethyl)cyclopropylcarbamate
CAS 1199792-79-4C12H14N4O2
![Benzyl N-[1-(hydroxymethyl)cyclopropyl]-N-methylcarbamate chemical structure, C13H17NO3, CAS 1445884-19-4](/s/MBZIJTWMDSPMJJ-UHFFFAOYSA-N.svg)
Benzyl N-[1-(hydroxymethyl)cyclopropyl]-N-methylcarbamate
CAS 1445884-19-4C13H17NO3
cis-2-Benzyloxycarbonylamino-cyclopropanecarboxylic acid ethyl ester
CAS 1421676-86-9C14H17NO4
Ethyl (1S,2R)-2-(phenylmethoxycarbonylamino)cyclopropane-1-carboxylate
C14H17NO4
amino}cyclopropane-1-carboxylic acid chemical structure, C15H19NO4, CAS 1692712-69-8](/s/DRPNUJIQTWFVOW-UHFFFAOYSA-N.svg)
1-{[(Benzyloxy)carbonyl](propan-2-yl)amino}cyclopropane-1-carboxylic acid
CAS 1692712-69-8C15H19NO4
![Benzyl N-[1-(2-bromoacetyl)cyclopropyl]carbamate chemical structure, C13H14BrNO3, CAS 1566334-59-5](/s/XPXXUQWEZBZLMN-UHFFFAOYSA-N.svg)
Benzyl N-[1-(2-bromoacetyl)cyclopropyl]carbamate
CAS 1566334-59-5C13H14BrNO3
amino}cyclopropane-1-carboxylic acid chemical structure, C13H15NO4, CAS 1702529-47-2](/s/FZPOADJMQUPNGY-UHFFFAOYSA-N.svg)
1-{[(Benzyloxy)carbonyl](methyl)amino}cyclopropane-1-carboxylic acid
CAS 1702529-47-2C13H15NO4
![rac-(1R,2R)-1-{[(Benzyloxy)carbonyl]amino}-2-(trifluoromethyl)cyclopropane-1-carboxylic acid chemical structure, C13H12F3NO4, CAS 1993318-69-6](/s/ZRVGYXSCVFOFGU-CABZTGNLSA-N.svg)
rac-(1R,2R)-1-{[(Benzyloxy)carbonyl]amino}-2-(trifluoromethyl)cyclopropane-1-carboxylic acid
CAS 1993318-69-6C13H12F3NO4
N-Cbz-1-(trifluoromethyl)cyclopropanamine
CAS 1873234-99-1C12H12F3NO2
![Benzyl N-[1-(2-hydroxyethyl)cyclopropyl]carbamate chemical structure, C13H17NO3, CAS 2680703-03-9](/s/FHUJFFWBSLUUHD-UHFFFAOYSA-N.svg)
Benzyl N-[1-(2-hydroxyethyl)cyclopropyl]carbamate
CAS 2680703-03-9C13H17NO3
![Ethyl (2E)-3-(1-{[(benzyloxy)carbonyl]amino}cyclopropyl)prop-2-enoate chemical structure, C16H19NO4, CAS 103500-24-9](/s/DMUGKDUKXOHJMZ-CMDGGOBGSA-N.svg)
Ethyl (2E)-3-(1-{[(benzyloxy)carbonyl]amino}cyclopropyl)prop-2-enoate
CAS 103500-24-9C16H19NO4
![rac-(1R,2R)-1-{[(Benzyloxy)carbonyl]amino}-2-methylcyclopropane-1-carboxylic acid chemical structure, C13H15NO4, CAS 2679939-62-7](/s/TWMCPQABOCXLDI-NOZJJQNGSA-N.svg)
rac-(1R,2R)-1-{[(Benzyloxy)carbonyl]amino}-2-methylcyclopropane-1-carboxylic acid
CAS 2679939-62-7C13H15NO4
![Benzyl N-[1-(aminomethyl)cyclopropyl]carbamate hydrochloride chemical structure, C12H17ClN2O2, CAS 2055841-99-9](/s/KVUKSIILMLYQQM-UHFFFAOYSA-N.svg)
Benzyl N-[1-(aminomethyl)cyclopropyl]carbamate hydrochloride
CAS 2055841-99-9C12H17ClN2O2
Benzyl N-(2-fluorocyclopropyl)carbamate
CAS 1822644-24-5C11H12FNO2
- Benzyl N-(2-cyanoethyl)-N-cyclopropylcarbamate1871245-34-9C14H16N2O2
- Benzyl N-cyclopropyl-N-(prop-2-en-1-yl)carbamate1861295-62-6C14H17NO2
- Ethyl 3-(1-(((benzyloxy)carbonyl)amino)cyclopropyl)-3-oxopropanoate2172999-50-5C16H19NO5
- Benzyl N-[2-(bromomethyl)cyclopropyl]carbamate1823213-39-3C12H14BrNO2
- Benzyl N-(1-ethynylcyclopropyl)carbamate1799662-29-5C13H13NO2
- 1-{[(Benzyloxy)carbonyl]amino}-2-methylcyclopropane-1-carboxylic acid2680668-72-6C13H15NO4
- N-Cbz-(1R,2R)-2-aminocyclopropan-1-ol2489613-08-1C11H13NO3
- N-Cbz-(1S,2R)-2-aminocyclopropan-1-ol2489613-11-6C11H13NO3
- Benzyl N-(1-cyanocyclopropyl)-N-methylcarbamate2273707-00-7C13H14N2O2
- Benzyl N-{1-[3-(chlorosulfonyl)propyl]cyclopropyl}carbamate2171970-33-3C14H18ClNO4S
- 1-Phenylprop-2-yn-1-yl N-cyclopropylcarbamate2167056-32-6C13H13NO2
- Benzyl N-[3-(chlorosulfonyl)propyl]-N-cyclopropylcarbamate2172178-65-1C14H18ClNO4S
- Benzyl N-[4-(chlorosulfonyl)butyl]-N-cyclopropylcarbamate2172492-21-4C15H20ClNO4S
- 2-(1-{[(Benzyloxy)carbonyl](methyl)amino}cyclopropyl)acetic acid2171981-99-8C14H17NO4
- Benzyl N-[2-(chlorosulfonyl)ethyl]-N-cyclopropylcarbamate2172471-24-6C13H16ClNO4S
- 3-(1-{[(Benzyloxy)carbonyl]amino}cyclopropyl)prop-2-ynoic acid2580228-97-1C14H13NO4
- rac-(1R,3R)-3-{[(Benzyloxy)carbonyl]amino}-2,2-dimethylcyclopropane-1-carboxylic acid2580091-38-7C14H17NO4
- 2-(1-{[(Benzyloxy)carbonyl]amino}cyclopropyl)propanoic acid2580248-64-0C14H17NO4
- (2S,3R)-2-{[(Benzyloxy)carbonyl](cyclopropyl)amino}-3-hydroxybutanoic acid2580093-46-3C15H19NO5
- 3-{[(Benzyloxy)carbonyl](cyclopropyl)amino}-4,4,4-trifluorobutanoic acid2639409-34-8C15H16F3NO4
- rac-Benzyl N-[(1R,2R)-2-(fluoromethyl)cyclopropyl]carbamate2679926-80-6C12H14FNO2
- Benzyl N-[1-(1-hydroxy-2-methoxyethyl)cyclopropyl]carbamate2680553-47-1C14H19NO4
- Benzyl N-cyclopropyl-N-[(2S)-2-hydroxypropyl]carbamate2679926-40-8C14H19NO3
- Benzyl N-(1-ethenylcyclopropyl)carbamate1852533-31-3C13H15NO2
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(NC(=S)Nc1ccccc1)C1CC18 chemicals
O=C(COc1ccccc1)NC1CC17 chemicals
c1ccc(CCOCC2CC2)cc16 chemicals
O=C(NN=Cc1ccccc1)C1CC15 chemicals
O=C(NNC(=O)C1CC1)c1ccccc15 chemicals
C(=Cc1ccccc1)C=NC1CC14 chemicals
O=C(CSc1ccccc1)NC1CC14 chemicals
O=C(Nc1ccccc1)C(=O)NC1CC14 chemicals
O=C(NCCc1ccccc1)C1CC13 chemicals
O=C(C=Cc1ccccc1)NC1CC13 chemicals
c1ccc(COCCC2CO2)cc13 chemicals
c1ccc(COCCC2CC2)cc12 chemicals