Murcko scaffold
Benzyl cyclopropylcarbamate scaffold
148 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 148
- With full pages
- 2
Scaffold SMILES
O=C(NC1CC1)OCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 148 chemicals
![1-{[(Benzyloxy)carbonyl]amino}-2,2-dimethylcyclopropane-1-carboxylic acid chemical structure, C14H17NO4, CAS 885951-76-8](/s/PUMIFCNKFTVNTF-UHFFFAOYSA-N.svg)
1-{[(Benzyloxy)carbonyl]amino}-2,2-dimethylcyclopropane-1-carboxylic acid
CAS 885951-76-8C14H17NO4
![1-{[(Benzyloxy)carbonyl]amino}cyclopropane-1-carboxylic acid chemical structure, C12H13NO4, CAS 84677-06-5](/s/KHINKCGJKZSHAJ-UHFFFAOYSA-N.svg)
1-{[(Benzyloxy)carbonyl]amino}cyclopropane-1-carboxylic acid
CAS 84677-06-5C12H13NO4
![Carbamic acid, [1-(aminothioxomethyl)cyclopropyl]-, phenylmethyl ester chemical structure, C12H14N2O2S, CAS 541528-07-8](/s/XQJVCZNKKNCTMY-UHFFFAOYSA-N.svg)
Carbamic acid, [1-(aminothioxomethyl)cyclopropyl]-, phenylmethyl ester
CAS 541528-07-8C12H14N2O2S
Methyl (1R)-1-(benzyloxycarbonylamino)-2,2-difluoro-cyclopropanecarboxylate
CAS 597555-98-1C13H13F2NO4
Ethyl 1-(((benzyloxy)carbonyl)amino)cyclopropanecarboxylate
CAS 85452-41-1C14H17NO4
Benzyl cyclopropylcarbamate
CAS 88048-43-5C11H13NO2
![Methyl 1-{[(benzyloxy)carbonyl]amino}cyclopropane-1-carboxylate chemical structure, C13H15NO4, CAS 84677-05-4](/s/FQNOQUWDRWTZDJ-UHFFFAOYSA-N.svg)
Methyl 1-{[(benzyloxy)carbonyl]amino}cyclopropane-1-carboxylate
CAS 84677-05-4C13H15NO4
![rac-(1R,2S)-1-{[(Benzyloxy)carbonyl]amino}-2-(propan-2-yl)cyclopropane-1-carboxylic acid chemical structure, C15H19NO4, CAS 123311-20-6](/s/UDBHSOJQFLLWSL-SWLSCSKDSA-N.svg)
rac-(1R,2S)-1-{[(Benzyloxy)carbonyl]amino}-2-(propan-2-yl)cyclopropane-1-carboxylic acid
CAS 123311-20-6C15H19NO4
![rel-(1R,2R)-2-(1-Methylethyl)-1-[[(phenylmethoxy)carbonyl]amino]cyclopropanecarboxylic acid chemical structure, C15H19NO4, CAS 123311-19-3](/s/UDBHSOJQFLLWSL-IUODEOHRSA-N.svg)
rel-(1R,2R)-2-(1-Methylethyl)-1-[[(phenylmethoxy)carbonyl]amino]cyclopropanecarboxylic acid
CAS 123311-19-3C15H19NO4
![Benzyl N-[(1R,2S)-2-fluorocyclopropyl]carbamate chemical structure, C11H12FNO2, CAS 1932529-76-4](/s/XKIFNDSUUQVBIM-VHSXEESVSA-N.svg)
Benzyl N-[(1R,2S)-2-fluorocyclopropyl]carbamate
CAS 1932529-76-4C11H12FNO2
![rac-(1R,2R)-1-{[(Benzyloxy)carbonyl]amino}-2-ethylcyclopropane-1-carboxylic acid chemical structure, C14H17NO4, CAS 173346-52-6](/s/ZLTSPEDKKVGPIX-BXUZGUMPSA-N.svg)
rac-(1R,2R)-1-{[(Benzyloxy)carbonyl]amino}-2-ethylcyclopropane-1-carboxylic acid
CAS 173346-52-6C14H17NO4
![[(1R)-1-(Benzyloxycarbonylamino)-2,2-difluoro-cyclopropyl]methyl acetate chemical structure, C14H15F2NO4, CAS 228580-18-5](/s/BALJVMPOADNGIL-CYBMUJFWSA-N.svg)
[(1R)-1-(Benzyloxycarbonylamino)-2,2-difluoro-cyclopropyl]methyl acetate
CAS 228580-18-5C14H15F2NO4
![Benzyl N-[(1R)-2,2-difluoro-1-(hydroxymethyl)cyclopropyl]carbamate chemical structure, C12H13F2NO3, CAS 228580-20-9](/s/VXZPBRSHUAANRR-LLVKDONJSA-N.svg)
Benzyl N-[(1R)-2,2-difluoro-1-(hydroxymethyl)cyclopropyl]carbamate
CAS 228580-20-9C12H13F2NO3
amino}acetic acid chemical structure, C13H15NO4, CAS 71922-64-0](/s/YGKNIMGNXSLCFF-UHFFFAOYSA-N.svg)
2-{[(Benzyloxy)carbonyl](cyclopropyl)amino}acetic acid
CAS 71922-64-0C13H15NO4
2-(1-(((Benzyloxy)carbonyl)amino)cyclopropyl)acetic acid
CAS 134363-82-9C13H15NO4
![rac-Methyl (1R,2S)-2-{[(benzyloxy)carbonyl]amino}cyclopropane-1-carboxylate chemical structure, C13H15NO4, CAS 53229-57-5](/s/LDUAAHZTNAGKCO-MNOVXSKESA-N.svg)
rac-Methyl (1R,2S)-2-{[(benzyloxy)carbonyl]amino}cyclopropane-1-carboxylate
CAS 53229-57-5C13H15NO4
Benzyl (1-(hydroxymethyl)cyclopropyl)carbamate
CAS 103500-22-7C12H15NO3
Benzyl N-cyclopropyl-N-(2-hydroxyethyl)carbamate
CAS 1153219-88-5C13H17NO3
![1-{[(Benzyloxy)carbonyl]amino}-2,2-difluorocyclopropane-1-carboxylic acid chemical structure, C12H11F2NO4, CAS 1240528-90-8](/s/PMJPXVCYHODXGE-UHFFFAOYSA-N.svg)
1-{[(Benzyloxy)carbonyl]amino}-2,2-difluorocyclopropane-1-carboxylic acid
CAS 1240528-90-8C12H11F2NO4
![2-{[(Benzyloxy)carbonyl]amino}-3-(trifluoromethyl)cyclopropane-1-carboxylic acid chemical structure, C13H12F3NO4, CAS 1240526-66-2](/s/JDHYIDIXFKGBMD-UHFFFAOYSA-N.svg)
2-{[(Benzyloxy)carbonyl]amino}-3-(trifluoromethyl)cyclopropane-1-carboxylic acid
CAS 1240526-66-2C13H12F3NO4
Benzyl (1-formylcyclopropyl)carbamate
CAS 103500-23-8C12H13NO3
![3-(1-{[(Benzyloxy)carbonyl]amino}cyclopropyl)propanoic acid chemical structure, C14H17NO4, CAS 2580236-62-8](/s/QAIVTBZOPGCKHE-UHFFFAOYSA-N.svg)
3-(1-{[(Benzyloxy)carbonyl]amino}cyclopropyl)propanoic acid
CAS 2580236-62-8C14H17NO4
Benzyl N-(1-carbamimidoylcyclopropyl)carbamate
CAS 1191123-51-9C12H15N3O2
Cbz-1-Amino-1-cyclopropanecarbonitrile
CAS 1159735-22-4C12H12N2O2
- (1-(((Benzyloxy)carbonyl)amino)cyclopropyl)methyl methanesulfonate1058137-81-7C13H17NO5S
- (1-{[1-Dimethylamino-meth-(e)-ylidene]-carbamoyl}-cyclopropyl)-carbamic acid benzyl ester1159733-65-9C15H19N3O3
- Ethyl 2-(Benzyloxycarbonylamino)-1-hydroxycyclopropanecarboxylate1255775-18-8C14H17NO5
- 2-(Benzyloxycarbonylamino)-1-hydroxycyclopropanecarboxylic acid1221492-33-6C12H13NO5
- 3-{[(Benzyloxy)carbonyl](cyclopropyl)amino}propanoic acid1179073-27-8C14H17NO4
- 2-{[(Benzyloxy)carbonyl](cyclopropyl)amino}butanoic acid1404878-68-7C15H19NO4
- Ethyl 2-(benzyloxycarbonylamino)-1-(tert-butyldimethylsilyloxy)cyclopropanecarboxylate1221493-32-8C20H31NO5Si
- 1 suppliersBenzyl N-(1-carbamimidoylcyclopropyl)carbamate, hydrochloride1191096-21-5C12H16ClN3O2
- Methyl 1-(methyl{[(phenylmethyl)oxy]carbonyl}amino)cyclopropanecarboxylate210576-30-0C14H17NO4
- Methyl ((1-(((benzyloxy)carbonyl)amino)cyclopropyl)methyl)glycinate1199792-77-2C15H20N2O4
- Methyl N-Boc-N-[[1-(Cbz-amino)cyclopropyl]methyl]glycinate1199792-78-3C20H28N2O6
- tert-Butyl 1-(((benzyloxy)carbonyl)amino)cyclopropane-1-carboxylate1159735-75-7C16H21NO4
- Benzyl 2-hydroxycyclopropylcarbamate1046469-19-5C11H13NO3
- Benzyl 2-methoxycyclopropylcarbamate1046469-20-8C12H15NO3
- Ethyl N-[(1-{[(benzyloxy)carbonyl]amino}cyclopropyl)methyl]glycinate851726-82-4C16H22N2O4
- 1-{[(Benzyloxy)carbonyl](ethyl)amino}cyclopropane-1-carboxylic acid1702611-69-5C14H17NO4
- Benzyl N-[1-(aminomethyl)cyclopropyl]carbamate1439909-08-6C12H16N2O2
- Benzyl 1-(bromomethyl)cyclopropylcarbamate1351376-39-0C12H14BrNO2
- Benzyl N-[1-({[(tert-butoxy)carbonyl]amino}methyl)cyclopropyl]carbamate1199792-80-7C17H24N2O4
- Benzyl N-(1-acetylcyclopropyl)carbamate2680887-97-0C13H15NO3
- Benzyl (1-(methoxy(methyl)carbamoyl)cyclopropyl)carbamate851726-81-3C14H18N2O4
- Ethyl 2-(((benzyloxy)carbonyl)amino)cyclopropanecarboxylate613261-18-0C14H17NO4
- Benzyl (1-(methoxymethyl)cyclopropyl)carbamate1029716-04-8C13H17NO3
- Methyl 2-(benzyloxycarbonylamino)cyclopropanecarboxylate2104635-40-5C13H15NO4
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(NC(=S)Nc1ccccc1)C1CC18 chemicals
O=C(COc1ccccc1)NC1CC17 chemicals
c1ccc(CCOCC2CC2)cc16 chemicals
O=C(NN=Cc1ccccc1)C1CC15 chemicals
O=C(NNC(=O)C1CC1)c1ccccc15 chemicals
C(=Cc1ccccc1)C=NC1CC14 chemicals
O=C(CSc1ccccc1)NC1CC14 chemicals
O=C(Nc1ccccc1)C(=O)NC1CC14 chemicals
O=C(NCCc1ccccc1)C1CC13 chemicals
O=C(C=Cc1ccccc1)NC1CC13 chemicals
c1ccc(COCCC2CO2)cc13 chemicals
c1ccc(COCCC2CC2)cc12 chemicals