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Murcko scaffold

Ring system with 2 rings and 15 atoms

10 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
10
With full pages
3
Scaffold SMILES

O=c1ccnc(NCc2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccnc(NCc2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-{[(4-Amino-3-hydroxyphenyl)methyl]amino}pyrimidin-4(3H)-one chemical structure, C11H12N4O2, CAS 920512-19-2
2-{[(4-Amino-3-hydroxyphenyl)methyl]amino}pyrimidin-4(3H)-one
CAS 920512-19-2C11H12N4O2
2-({[3,5-Bis(trifluoromethyl)phenyl]methyl}amino)-N-hydroxy-4-oxo-1,4-dihydropyrimidine-5-carboxamide chemical structure, C14H10F6N4O3, CAS 1520083-61-7
2-({[3,5-Bis(trifluoromethyl)phenyl]methyl}amino)-N-hydroxy-4-oxo-1,4-dihydropyrimidine-5-carboxamide
CAS 1520083-61-7C14H10F6N4O3
6-Methyl-2-[(phenylmethyl)amino]-4(3H)-pyrimidinone chemical structure, C12H13N3O, CAS 88637-00-7
6-Methyl-2-[(phenylmethyl)amino]-4(3H)-pyrimidinone
CAS 88637-00-7C12H13N3O
2-(Benzylamino)-6-fluoropyrimidin-4(1H)-one chemical structure, C11H10FN3O, CAS 189003-13-2
2-(Benzylamino)-6-fluoropyrimidin-4(1H)-one
CAS 189003-13-2C11H10FN3O
2-[Benzyl(methyl)amino]-6-methylpyrimidin-4(3H)-one chemical structure, C13H15N3O, CAS 331972-28-2
2-[Benzyl(methyl)amino]-6-methylpyrimidin-4(3H)-one
CAS 331972-28-2C13H15N3O
2-{[(4-Chlorophenyl)methyl]amino}-6-methyl-3,4-dihydropyrimidin-4-one chemical structure, C12H12ClN3O, CAS 714214-12-7
2-{[(4-Chlorophenyl)methyl]amino}-6-methyl-3,4-dihydropyrimidin-4-one
CAS 714214-12-7C12H12ClN3O
6-Amino-2-(benzylamino)pyrimidin-4(3H)-one chemical structure, C11H12N4O, CAS 104296-01-7
6-Amino-2-(benzylamino)pyrimidin-4(3H)-one
CAS 104296-01-7C11H12N4O
2-((4-Fluorobenzyl)amino)-6-methylpyrimidin-4(3H)-one chemical structure, C12H12FN3O, CAS 880453-54-3
2-((4-Fluorobenzyl)amino)-6-methylpyrimidin-4(3H)-one
CAS 880453-54-3C12H12FN3O
5,6-Diamino-2-(benzylamino)pyrimidin-4(1H)-one chemical structure, C11H13N5O, CAS 61693-27-4
5,6-Diamino-2-(benzylamino)pyrimidin-4(1H)-one
CAS 61693-27-4C11H13N5O
Butyl 1,6-dihydro-6-oxo-2-[(phenylmethyl)amino]-4-pyrimidinecarboxylate chemical structure, C16H19N3O3, CAS 1244017-23-9
Butyl 1,6-dihydro-6-oxo-2-[(phenylmethyl)amino]-4-pyrimidinecarboxylate
CAS 1244017-23-9C16H19N3O3