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Murcko scaffold

Ring system with 3 rings and 18 atoms

4 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
4
With full pages
3
Scaffold SMILES

O=C(COc1ccccc1)N1CC2CCCC1C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)N1CC2CCCC1C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

2-(2,6-Dimethylphenoxy)-1-(1,3,3-trimethyl-6-azabicyclo[3.2.1]oct-6-yl)ethanone chemical structure, C20H29NO2, CAS 627055-77-0
2-(2,6-Dimethylphenoxy)-1-(1,3,3-trimethyl-6-azabicyclo[3.2.1]oct-6-yl)ethanone
CAS 627055-77-0C20H29NO2
2-(4-Methoxyphenoxy)-1-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)ethanone chemical structure, C19H27NO3, CAS 510724-28-4
2-(4-Methoxyphenoxy)-1-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)ethanone
CAS 510724-28-4C19H27NO3
2-(2-Methoxyphenoxy)-1-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)ethanone chemical structure, C19H27NO3, CAS 694518-13-3
2-(2-Methoxyphenoxy)-1-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)ethanone
CAS 694518-13-3C19H27NO3
3-Ethoxy-4-(2-oxo-2-{1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl}ethoxy)benzaldehyde chemical structure, C21H29NO4, CAS 571150-07-7
3-Ethoxy-4-(2-oxo-2-{1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl}ethoxy)benzaldehyde
CAS 571150-07-7C21H29NO4