Murcko scaffold
4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline scaffold
31 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 24
- Chemicals
- 31
- With full pages
- 3
Scaffold SMILES
c1ccc(-c2nn3c(c2-c2ccnc4ccccc24)CCC3)nc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 31 of 31 chemicals
Galunisertib
CAS 700874-72-2C22H19N5O
![Methyl 4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxylate chemical structure, C22H18N4O2, CAS 476475-43-1](/s/QNCMNBKPTMWICH-UHFFFAOYSA-N.svg)
Methyl 4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxylate
CAS 476475-43-1C22H18N4O2
![6-Bromo-4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline chemical structure, C20H15BrN4, CAS 476474-31-4](/s/IBVWKPKFYZDRFF-UHFFFAOYSA-N.svg)
6-Bromo-4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
CAS 476474-31-4C20H15BrN4
![4-(2-(6-Bromopyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline chemical structure, C20H15BrN4, CAS 476475-03-3](/s/KZMBKCUGOJXAGQ-UHFFFAOYSA-N.svg)
4-(2-(6-Bromopyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
CAS 476475-03-3C20H15BrN4
Galunisertib monohydrate
CAS 924898-09-9C22H21N5O2
![4-(2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carbonitrile chemical structure, C22H17N5, CAS 924898-13-5](/s/JKLLRKDEWNJNFG-UHFFFAOYSA-N.svg)
4-(2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carbonitrile
CAS 924898-13-5C22H17N5
![2-[4-(2-Pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-quinolin-7-yloxy]-ethanol chemical structure, C22H20N4O2, CAS 700874-74-4](/s/PTBGTMHQBJAGGL-UHFFFAOYSA-N.svg)
2-[4-(2-Pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-quinolin-7-yloxy]-ethanol
CAS 700874-74-4C22H20N4O2
![7-Ethoxy-4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline chemical structure, C23H22N4O, CAS 737791-24-1](/s/SGMXHEIWJQTVMJ-UHFFFAOYSA-N.svg)
7-Ethoxy-4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
CAS 737791-24-1C23H22N4O
![4-(2-(6-Methoxypyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline chemical structure, C21H18N4O, CAS 476476-03-6](/s/IFDGXFRJVUAOKM-UHFFFAOYSA-N.svg)
4-(2-(6-Methoxypyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
CAS 476476-03-6C21H18N4O
![7-Bromo-4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline chemical structure, C21H17BrN4, CAS 476474-61-0](/s/PCKFABJLKSXQEV-UHFFFAOYSA-N.svg)
7-Bromo-4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
CAS 476474-61-0C21H17BrN4
![7-Methoxy-4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline chemical structure, C21H18N4O, CAS 476474-40-5](/s/YOXUJEKTIANZNU-UHFFFAOYSA-N.svg)
7-Methoxy-4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
CAS 476474-40-5C21H18N4O
![6-(3-(Quinolin-4-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-2-yl)picolinic acid chemical structure, C21H16N4O2, CAS 749843-99-0](/s/FTOWKSWJLZAFRC-UHFFFAOYSA-N.svg)
6-(3-(Quinolin-4-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-2-yl)picolinic acid
CAS 749843-99-0C21H16N4O2
Dihydropyrrolopyrazole, 7f
CAS 476474-62-1C22H17F3N4O
![4-[2-(6-Methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-quinoline chemical structure, C21H18N4, CAS 476475-13-5](/s/CQFMEEGANZACLR-UHFFFAOYSA-N.svg)
4-[2-(6-Methyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-quinoline
CAS 476475-13-5C21H18N4
![6-Bromo-4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline chemical structure, C21H17BrN4, CAS 476474-52-9](/s/BJBCSMYAHPXGJA-UHFFFAOYSA-N.svg)
6-Bromo-4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
CAS 476474-52-9C21H17BrN4
![4-(2-(4-Chloropyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline chemical structure, C20H15ClN4, CAS 476475-18-0](/s/DIYJJYHGDKJAIP-UHFFFAOYSA-N.svg)
4-(2-(4-Chloropyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
CAS 476475-18-0C20H15ClN4
![4-(2-(6-Chloropyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline chemical structure, C20H15ClN4, CAS 476478-02-1](/s/CLOYZHLLEAYAGZ-UHFFFAOYSA-N.svg)
4-(2-(6-Chloropyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
CAS 476478-02-1C20H15ClN4
![4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-(trifluoromethyl)quinoline chemical structure, C22H17F3N4, CAS 476474-53-0](/s/PXJSURXYZLWKPA-UHFFFAOYSA-N.svg)
4-[2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-(trifluoromethyl)quinoline
CAS 476474-53-0C22H17F3N4
![7-Methoxy-4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline chemical structure, C22H20N4O, CAS 476474-64-3](/s/SGBDJDBCJFNUJF-UHFFFAOYSA-N.svg)
7-Methoxy-4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
CAS 476474-64-3C22H20N4O
![4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline chemical structure, C20H16N4, CAS 737791-20-7](/s/AOTADNCHLKUEAX-UHFFFAOYSA-N.svg)
4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline
CAS 737791-20-7C20H16N4
![Methyl 4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxylate chemical structure, C23H20N4O2, CAS 476475-44-2](/s/PYUBAZVUCQOMKF-UHFFFAOYSA-N.svg)
Methyl 4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxylate
CAS 476475-44-2C23H20N4O2
![4-(2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-7-carboxamide chemical structure, C22H19N5O, CAS 476477-15-3](/s/PBLNPFVCOVYAKI-UHFFFAOYSA-N.svg)
4-(2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-7-carboxamide
CAS 476477-15-3C22H19N5O
![Methyl 6-(3-(quinolin-4-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-2-yl)picolinate chemical structure, C22H18N4O2, CAS 476475-27-1](/s/RQMSVRBTBHONAQ-UHFFFAOYSA-N.svg)
Methyl 6-(3-(quinolin-4-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-2-yl)picolinate
CAS 476475-27-1C22H18N4O2
![Methyl 4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-7-carboxylate chemical structure, C23H20N4O2, CAS 476475-45-3](/s/WUSBWWWXKVBGOW-UHFFFAOYSA-N.svg)
Methyl 4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-7-carboxylate
CAS 476475-45-3C23H20N4O2
- N-[4-[2-(6-Methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carbonyl]carbamoyl chloride1713284-84-4C23H18ClN5O2
- 4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-ol476474-11-0C20H16N4O
- 4-(2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-ol476477-67-5C21H18N4O
- 4-[2-(6-Methyl-1-oxidopyridin-1-ium-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide1788893-67-3C22H19N5O2
- 7-Quinolinecarboxamide, 4-[5,6-dihydro-2-(2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-N-methyl-476476-94-5C22H19N5O
- 4-[2-(6-Methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinolin-6-ol2426547-83-1C21H18N4O
- [1-Hydroxy-1-phosphono-4-[2-[4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl]oxyethoxycarbonylamino]butyl]phosphonic acid2409546-40-1C27H31N5O10P2