CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 20 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
8
With full pages
3
Scaffold SMILES

O=C1c2cccc3cccc(c23)C(=O)N1c1cn[nH]c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1c2cccc3cccc(c23)C(=O)N1c1cn[nH]c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2-(3,5-Dimethyl-1H-pyrazol-4-yl)-6-nitro-1H-benzo[de]isoquinoline-1,3(2H)-dione chemical structure, C17H12N4O4, CAS 357613-34-4
2-(3,5-Dimethyl-1H-pyrazol-4-yl)-6-nitro-1H-benzo[de]isoquinoline-1,3(2H)-dione
CAS 357613-34-4C17H12N4O4
6-Amino-2-(1,3-dimethylpyrazol-4-yl)benzo[de]isoquinoline-1,3-dione chemical structure, C17H14N4O2, CAS 85703-75-9
6-Amino-2-(1,3-dimethylpyrazol-4-yl)benzo[de]isoquinoline-1,3-dione
CAS 85703-75-9C17H14N4O2
6-Amino-2-(3,5-dimethyl-1H-pyrazol-4-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione chemical structure, C17H14N4O2, CAS 377065-48-0
6-Amino-2-(3,5-dimethyl-1H-pyrazol-4-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
CAS 377065-48-0C17H14N4O2
6-Bromo-2-(3,5-dimethyl-1H-pyrazol-4-yl)-1H-benz[de]isoquinoline-1,3(2H)-dione chemical structure, C17H12BrN3O2, CAS 51461-22-4
6-Bromo-2-(3,5-dimethyl-1H-pyrazol-4-yl)-1H-benz[de]isoquinoline-1,3(2H)-dione
CAS 51461-22-4C17H12BrN3O2
5-Bromo-2-(3,5-dimethyl-1H-pyrazol-4-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione chemical structure, C17H12BrN3O2, CAS 489407-27-4
5-Bromo-2-(3,5-dimethyl-1H-pyrazol-4-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
CAS 489407-27-4C17H12BrN3O2
6-Bromo-2-(1-ethyl-3,5-dimethyl-1H-pyrazol-4-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione chemical structure, C19H16BrN3O2, CAS 434299-14-6
6-Bromo-2-(1-ethyl-3,5-dimethyl-1H-pyrazol-4-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
CAS 434299-14-6C19H16BrN3O2
4-(6-Methoxy-1,3-dioxo-1H-benz(de)isoquinolin-2(3H)-yl)-1,2,3,5-tetramethyl-1H-pyrazolium methyl sulphate chemical structure, C21H23N3O7S, CAS 60317-11-5
4-(6-Methoxy-1,3-dioxo-1H-benz(de)isoquinolin-2(3H)-yl)-1,2,3,5-tetramethyl-1H-pyrazolium methyl sulphate
CAS 60317-11-5C21H23N3O7S
2-(3,5-Dimethyl-1H-pyrazol-4-yl)-6-methoxy-1H-benz(de)isoquinoline-1,3(2H)-dione chemical structure, C18H15N3O3, CAS 85480-81-5
2-(3,5-Dimethyl-1H-pyrazol-4-yl)-6-methoxy-1H-benz(de)isoquinoline-1,3(2H)-dione
CAS 85480-81-5C18H15N3O3