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Murcko scaffold

Ring system with 4 rings and 26 atoms

26 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
26
With full pages
9
Scaffold SMILES

O=c1oc2cc(OCc3ccccc3)ccc2cc1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1oc2cc(OCc3ccccc3)ccc2cc1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

4-{[(3-Benzyl-4-methyl-2-oxo-2H-chromen-7-yl)oxy]methyl}benzoic acid chemical structure, C25H20O5, CAS 376376-66-8
4-{[(3-Benzyl-4-methyl-2-oxo-2H-chromen-7-yl)oxy]methyl}benzoic acid
CAS 376376-66-8C25H20O5
3-Benzyl-7-((4-methoxybenzyl)oxy)-4-methyl-2H-chromen-2-one chemical structure, C25H22O4, CAS 374764-06-4
3-Benzyl-7-((4-methoxybenzyl)oxy)-4-methyl-2H-chromen-2-one
CAS 374764-06-4C25H22O4
3-Benzyl-4,8-dimethyl-7-[(3,4,5-trimethoxybenzyl)oxy]-2H-chromen-2-one chemical structure, C28H28O6, CAS 376385-08-9
3-Benzyl-4,8-dimethyl-7-[(3,4,5-trimethoxybenzyl)oxy]-2H-chromen-2-one
CAS 376385-08-9C28H28O6
3-Benzyl-7-[(3-methoxybenzyl)oxy]-4-methyl-2H-chromen-2-one chemical structure, C25H22O4, CAS 374765-88-5
3-Benzyl-7-[(3-methoxybenzyl)oxy]-4-methyl-2H-chromen-2-one
CAS 374765-88-5C25H22O4
3-Benzyl-4-methyl-7-[(3,4,5-trimethoxybenzyl)oxy]-2H-chromen-2-one chemical structure, C27H26O6, CAS 376385-38-5
3-Benzyl-4-methyl-7-[(3,4,5-trimethoxybenzyl)oxy]-2H-chromen-2-one
CAS 376385-38-5C27H26O6
3-Benzyl-7-[(2-methoxybenzyl)oxy]-4-methyl-2H-chromen-2-one chemical structure, C25H22O4, CAS 374767-09-6
3-Benzyl-7-[(2-methoxybenzyl)oxy]-4-methyl-2H-chromen-2-one
CAS 374767-09-6C25H22O4
3-Benzyl-7-[(2-fluorobenzyl)oxy]-4-methyl-2H-chromen-2-one chemical structure, C24H19FO3, CAS 307549-32-2
3-Benzyl-7-[(2-fluorobenzyl)oxy]-4-methyl-2H-chromen-2-one
CAS 307549-32-2C24H19FO3
3-Benzyl-7-[(2,6-dichlorobenzyl)oxy]-4-methyl-2H-chromen-2-one chemical structure, C24H18Cl2O3, CAS 307549-33-3
3-Benzyl-7-[(2,6-dichlorobenzyl)oxy]-4-methyl-2H-chromen-2-one
CAS 307549-33-3C24H18Cl2O3
3-Benzyl-7-[(4-fluorobenzyl)oxy]-4-methyl-2H-chromen-2-one chemical structure, C24H19FO3, CAS 307549-36-6
3-Benzyl-7-[(4-fluorobenzyl)oxy]-4-methyl-2H-chromen-2-one
CAS 307549-36-6C24H19FO3
AK-968/12686106 chemical structure, C24H19NO5, CAS 6222-31-7
AK-968/12686106
CAS 6222-31-7C24H19NO5
4-(((3-Benzyl-4,8-dimethyl-2-oxo-2H-chromen-7-yl)oxy)methyl)benzoic acid chemical structure, C26H22O5, CAS 376379-53-2
4-(((3-Benzyl-4,8-dimethyl-2-oxo-2H-chromen-7-yl)oxy)methyl)benzoic acid
CAS 376379-53-2C26H22O5
3-Benzyl-7-[(2-methoxybenzyl)oxy]-4,8-dimethyl-2H-chromen-2-one chemical structure, C26H24O4, CAS 374765-35-2
3-Benzyl-7-[(2-methoxybenzyl)oxy]-4,8-dimethyl-2H-chromen-2-one
CAS 374765-35-2C26H24O4
3-Benzyl-7-[(3-methoxybenzyl)oxy]-4,8-dimethyl-2H-chromen-2-one chemical structure, C26H24O4, CAS 374767-45-0
3-Benzyl-7-[(3-methoxybenzyl)oxy]-4,8-dimethyl-2H-chromen-2-one
CAS 374767-45-0C26H24O4
3-Benzyl-6-chloro-7-[(2-methoxybenzyl)oxy]-4-methyl-2H-chromen-2-one chemical structure, C25H21ClO4, CAS 670244-36-7
3-Benzyl-6-chloro-7-[(2-methoxybenzyl)oxy]-4-methyl-2H-chromen-2-one
CAS 670244-36-7C25H21ClO4
3-Benzyl-7-[(2-chloro-6-fluorobenzyl)oxy]-4-methyl-2H-chromen-2-one chemical structure, C24H18ClFO3, CAS 307549-34-4
3-Benzyl-7-[(2-chloro-6-fluorobenzyl)oxy]-4-methyl-2H-chromen-2-one
CAS 307549-34-4C24H18ClFO3
Methyl 4-{[(3-benzyl-4-methyl-2-oxo-2H-chromen-7-yl)oxy]methyl}benzoate chemical structure, C26H22O5, CAS 374766-10-6
Methyl 4-{[(3-benzyl-4-methyl-2-oxo-2H-chromen-7-yl)oxy]methyl}benzoate
CAS 374766-10-6C26H22O5
3-Benzyl-6-chloro-7-[(4-methoxybenzyl)oxy]-4-methyl-2H-chromen-2-one chemical structure, C25H21ClO4, CAS 898797-12-1
3-Benzyl-6-chloro-7-[(4-methoxybenzyl)oxy]-4-methyl-2H-chromen-2-one
CAS 898797-12-1C25H21ClO4
3-Benzyl-6-chloro-7-[(3-methoxybenzyl)oxy]-4-methyl-2H-chromen-2-one chemical structure, C25H21ClO4, CAS 577699-25-3
3-Benzyl-6-chloro-7-[(3-methoxybenzyl)oxy]-4-methyl-2H-chromen-2-one
CAS 577699-25-3C25H21ClO4
Methyl 4-{[(3-benzyl-4,8-dimethyl-2-oxo-2H-chromen-7-yl)oxy]methyl}benzoate chemical structure, C27H24O5, CAS 374762-51-3
Methyl 4-{[(3-benzyl-4,8-dimethyl-2-oxo-2H-chromen-7-yl)oxy]methyl}benzoate
CAS 374762-51-3C27H24O5
3-Benzyl-7-[(4-methoxybenzyl)oxy]-4,8-dimethyl-2H-chromen-2-one chemical structure, C26H24O4, CAS 374767-38-1
3-Benzyl-7-[(4-methoxybenzyl)oxy]-4,8-dimethyl-2H-chromen-2-one
CAS 374767-38-1C26H24O4
3-Benzyl-7-(benzyloxy)-4-methyl-2H-chromen-2-one chemical structure, C24H20O3, CAS 313953-10-5
3-Benzyl-7-(benzyloxy)-4-methyl-2H-chromen-2-one
CAS 313953-10-5C24H20O3
3-Benzyl-7-[(2,4-dichlorobenzyl)oxy]-4,8-dimethyl-2H-chromen-2-one chemical structure, C25H20Cl2O3, CAS 380209-74-5
3-Benzyl-7-[(2,4-dichlorobenzyl)oxy]-4,8-dimethyl-2H-chromen-2-one
CAS 380209-74-5C25H20Cl2O3
2-(3-Benzyl-4,8-dimethyl-2-oxochromen-7-yl)oxy-2-phenylacetic acid chemical structure, C26H22O5, CAS 500204-24-0
2-(3-Benzyl-4,8-dimethyl-2-oxochromen-7-yl)oxy-2-phenylacetic acid
CAS 500204-24-0C26H22O5
Methyl 2-[(3-benzyl-4,8-dimethyl-2-oxo-2H-chromen-7-yl)oxy]-2-phenylacetate chemical structure, C27H24O5, CAS 670243-25-1
Methyl 2-[(3-benzyl-4,8-dimethyl-2-oxo-2H-chromen-7-yl)oxy]-2-phenylacetate
CAS 670243-25-1C27H24O5