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Murcko scaffold

N,1-diphenylmethanesulfonamide scaffold

176 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
176
With full pages
1
Scaffold SMILES

O=S(=O)(Cc1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N,1-diphenylmethanesulfonamide page
Murcko scaffold O=S(=O)(Cc1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 176 of 176 chemicals

2-{[(4-Methylbenzyl)sulfonyl]amino}benzamide chemical structure, C15H16N2O3S, CAS 950231-50-2
2-{[(4-Methylbenzyl)sulfonyl]amino}benzamide
CAS 950231-50-2C15H16N2O3S
N-(3-{[(4-Methylbenzyl)sulfonyl]amino}phenyl)acetamide chemical structure, C16H18N2O3S, CAS 950233-00-8
N-(3-{[(4-Methylbenzyl)sulfonyl]amino}phenyl)acetamide
CAS 950233-00-8C16H18N2O3S
N-[3-(2-Bromoacetyl)phenyl]benzenemethanesulfonamide chemical structure, C15H14BrNO3S, CAS 193761-43-2
N-[3-(2-Bromoacetyl)phenyl]benzenemethanesulfonamide
CAS 193761-43-2C15H14BrNO3S
1-(4-Chlorophenyl)-N-(2,4-dimethylphenyl)methanesulfonamide chemical structure, C15H16ClNO2S, CAS 880323-74-0
1-(4-Chlorophenyl)-N-(2,4-dimethylphenyl)methanesulfonamide
CAS 880323-74-0C15H16ClNO2S
N-(2-Chlorophenyl)-1-(4-chlorophenyl)methanesulfonamide chemical structure, C13H11Cl2NO2S, CAS 880323-40-0
N-(2-Chlorophenyl)-1-(4-chlorophenyl)methanesulfonamide
CAS 880323-40-0C13H11Cl2NO2S
1-(4-Chlorophenyl)-N-(3-methoxyphenyl)methanesulfonamide chemical structure, C14H14ClNO3S, CAS 880323-54-6
1-(4-Chlorophenyl)-N-(3-methoxyphenyl)methanesulfonamide
CAS 880323-54-6C14H14ClNO3S
1-(4-Chlorophenyl)-N-(2,4-dimethoxyphenyl)methanesulfonamide chemical structure, C15H16ClNO4S, CAS 880322-31-6
1-(4-Chlorophenyl)-N-(2,4-dimethoxyphenyl)methanesulfonamide
CAS 880322-31-6C15H16ClNO4S
1-(4-Chlorophenyl)-N-(2,4-difluorophenyl)methanesulfonamide chemical structure, C13H10ClF2NO2S, CAS 880323-46-6
1-(4-Chlorophenyl)-N-(2,4-difluorophenyl)methanesulfonamide
CAS 880323-46-6C13H10ClF2NO2S
1-(4-Chlorophenyl)-N-(3,4-difluorophenyl)methanesulfonamide chemical structure, C13H10ClF2NO2S, CAS 931826-71-0
1-(4-Chlorophenyl)-N-(3,4-difluorophenyl)methanesulfonamide
CAS 931826-71-0C13H10ClF2NO2S
2-Chloro-5-[[(phenylmethyl)sulfonyl]amino]benzeneacetic acid chemical structure, C15H14ClNO4S, CAS 409082-06-0
2-Chloro-5-[[(phenylmethyl)sulfonyl]amino]benzeneacetic acid
CAS 409082-06-0C15H14ClNO4S
Benzoic acid, p-alpha-toluenesulfonamido-, sodium salt chemical structure, C14H12NNaO4S, CAS 64050-44-8
Benzoic acid, p-alpha-toluenesulfonamido-, sodium salt
CAS 64050-44-8C14H12NNaO4S
2-(4-((4-Fluorophenyl)methylsulfonamido)phenyl)acetamide chemical structure, C15H15FN2O3S, CAS 1070962-05-8
2-(4-((4-Fluorophenyl)methylsulfonamido)phenyl)acetamide
CAS 1070962-05-8C15H15FN2O3S
N-Methyl-2-[4-(phenylmethanesulfonamido)phenyl]acetamide chemical structure, C16H18N2O3S, CAS 1060262-96-5
N-Methyl-2-[4-(phenylmethanesulfonamido)phenyl]acetamide
CAS 1060262-96-5C16H18N2O3S
2-{4-[(4-Chlorophenyl)methanesulfonamido]phenyl}-N-methylacetamide chemical structure, C16H17ClN2O3S, CAS 1060247-55-3
2-{4-[(4-Chlorophenyl)methanesulfonamido]phenyl}-N-methylacetamide
CAS 1060247-55-3C16H17ClN2O3S
2-{4-[(2-Chlorophenyl)methanesulfonamido]phenyl}-N-(2-methoxyethyl)acetamide chemical structure, C18H21ClN2O4S, CAS 1060295-77-3
2-{4-[(2-Chlorophenyl)methanesulfonamido]phenyl}-N-(2-methoxyethyl)acetamide
CAS 1060295-77-3C18H21ClN2O4S
4-Cyano-N-(2,4-dimethylphenyl)benzenemethanesulfonamide chemical structure, C16H16N2O2S, CAS 1041558-35-3
4-Cyano-N-(2,4-dimethylphenyl)benzenemethanesulfonamide
CAS 1041558-35-3C16H16N2O2S
1-[4-(Aminomethyl)phenyl]-N-phenylmethanesulfonamide chemical structure, C14H16N2O2S, CAS 1041556-68-6
1-[4-(Aminomethyl)phenyl]-N-phenylmethanesulfonamide
CAS 1041556-68-6C14H16N2O2S
1-(4-Cyanophenyl)-N-phenylmethanesulfonamide chemical structure, C14H12N2O2S, CAS 1040026-51-4
1-(4-Cyanophenyl)-N-phenylmethanesulfonamide
CAS 1040026-51-4C14H12N2O2S
1-(4-Aminophenyl)-N-(4-methoxyphenyl)methanesulfonamide chemical structure, C14H16N2O3S, CAS 1040033-29-1
1-(4-Aminophenyl)-N-(4-methoxyphenyl)methanesulfonamide
CAS 1040033-29-1C14H16N2O3S
1-(2-Cyanophenyl)-N-phenylmethanesulfonamide chemical structure, C14H12N2O2S, CAS 27350-15-8
1-(2-Cyanophenyl)-N-phenylmethanesulfonamide
CAS 27350-15-8C14H12N2O2S
1-(2-Fluorophenyl)-N-(4-nitrophenyl)methanesulfonamide chemical structure, C13H11FN2O4S, CAS 1171990-83-2
1-(2-Fluorophenyl)-N-(4-nitrophenyl)methanesulfonamide
CAS 1171990-83-2C13H11FN2O4S
2-(4-((3-Fluorophenyl)methylsulfonamido)phenyl)-N-(2,2,2-trifluoroethyl)acetamide chemical structure, C17H16F4N2O3S, CAS 1235282-17-3
2-(4-((3-Fluorophenyl)methylsulfonamido)phenyl)-N-(2,2,2-trifluoroethyl)acetamide
CAS 1235282-17-3C17H16F4N2O3S
2-(4-((2-Chlorophenyl)methylsulfonamido)phenyl)-N-(2,2,2-trifluoroethyl)acetamide chemical structure, C17H16ClF3N2O3S, CAS 1234827-37-2
2-(4-((2-Chlorophenyl)methylsulfonamido)phenyl)-N-(2,2,2-trifluoroethyl)acetamide
CAS 1234827-37-2C17H16ClF3N2O3S
3-(Aminomethyl)-N-(5-fluoro-2-methylphenyl)benzenemethanesulfonamide chemical structure, C15H17FN2O2S, CAS 1182757-93-2
3-(Aminomethyl)-N-(5-fluoro-2-methylphenyl)benzenemethanesulfonamide
CAS 1182757-93-2C15H17FN2O2S