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Murcko scaffold

Ring system with 3 rings and 19 atoms

30 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
30
With full pages
2
Scaffold SMILES

O=C1CC2CCC1(CS(=O)(=O)Nc1ccccc1)C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC2CCC1(CS(=O)(=O)Nc1ccccc1)C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

C16H20Fno3S chemical structure, C16H20FNO3S, CAS 1274904-29-8
C16H20Fno3S
CAS 1274904-29-8C16H20FNO3S
(7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)-N-methyl-N-phenylmethanesulfonamide chemical structure, C17H23NO3S, CAS 13144-52-0
(7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)-N-methyl-N-phenylmethanesulfonamide
CAS 13144-52-0C17H23NO3S
1-(7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)-N-(3-methylphenyl)methanesulfonamide chemical structure, C17H23NO3S, CAS 111385-23-0
1-(7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)-N-(3-methylphenyl)methanesulfonamide
CAS 111385-23-0C17H23NO3S
1-((((3-Fluorophenyl)amino)sulfonyl)methyl)-7,7-dimethylbicyclo[2.2.1]heptan-2-one chemical structure, C16H20FNO3S, CAS 453582-61-1
1-((((3-Fluorophenyl)amino)sulfonyl)methyl)-7,7-dimethylbicyclo[2.2.1]heptan-2-one
CAS 453582-61-1C16H20FNO3S
N-(2,4-Difluorophenyl)(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methanesulfonamide chemical structure, C16H19F2NO3S, CAS 1022105-84-5
N-(2,4-Difluorophenyl)(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methanesulfonamide
CAS 1022105-84-5C16H19F2NO3S
1-(7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)-N-[3-(trifluoromethyl)phenyl]methanesulfonamide chemical structure, C17H20F3NO3S, CAS 379250-97-2
1-(7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)-N-[3-(trifluoromethyl)phenyl]methanesulfonamide
CAS 379250-97-2C17H20F3NO3S
1-(7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)-N-(3,5-dimethylphenyl)methanesulfonamide chemical structure, C18H25NO3S, CAS 627844-47-7
1-(7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)-N-(3,5-dimethylphenyl)methanesulfonamide
CAS 627844-47-7C18H25NO3S
N-(4-Butylphenyl)-1-{7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl}methanesulfonamide chemical structure, C20H29NO3S, CAS 627844-46-6
N-(4-Butylphenyl)-1-{7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl}methanesulfonamide
CAS 627844-46-6C20H29NO3S
1-{7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl}-N-(2-methylphenyl)methanesulfonamide chemical structure, C17H23NO3S, CAS 111465-88-4
1-{7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl}-N-(2-methylphenyl)methanesulfonamide
CAS 111465-88-4C17H23NO3S
1-{7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl}-N-(3,4-dimethylphenyl)methanesulfonamide chemical structure, C18H25NO3S, CAS 379248-36-9
1-{7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl}-N-(3,4-dimethylphenyl)methanesulfonamide
CAS 379248-36-9C18H25NO3S
N-(3-Chloro-4-fluorophenyl)-1-{7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl}methanesulfonamide chemical structure, C16H19ClFNO3S, CAS 379248-82-5
N-(3-Chloro-4-fluorophenyl)-1-{7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl}methanesulfonamide
CAS 379248-82-5C16H19ClFNO3S
7,7-Dimethyl-1-((((4-(isopropyl)phenyl)amino)sulfonyl)methyl)bicyclo[2.2.1]heptan-2-one chemical structure, C19H27NO3S, CAS 627844-63-7
7,7-Dimethyl-1-((((4-(isopropyl)phenyl)amino)sulfonyl)methyl)bicyclo[2.2.1]heptan-2-one
CAS 627844-63-7C19H27NO3S
1-((((3,5-Dichlorophenyl)amino)sulfonyl)methyl)-7,7-dimethylbicyclo[2.2.1]heptan-2-one chemical structure, C16H19Cl2NO3S, CAS 627844-53-5
1-((((3,5-Dichlorophenyl)amino)sulfonyl)methyl)-7,7-dimethylbicyclo[2.2.1]heptan-2-one
CAS 627844-53-5C16H19Cl2NO3S
7,7-Dimethyl-1-((((4-(trifluoromethoxy)phenyl)amino)sulfonyl)methyl)bicyclo[2.2.1]heptan-2-one chemical structure, C17H20F3NO4S, CAS 1024169-38-7
7,7-Dimethyl-1-((((4-(trifluoromethoxy)phenyl)amino)sulfonyl)methyl)bicyclo[2.2.1]heptan-2-one
CAS 1024169-38-7C17H20F3NO4S
N-(3-Bromophenyl)(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methanesulfonamide chemical structure, C16H20BrNO3S, CAS 133232-73-2
N-(3-Bromophenyl)(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methanesulfonamide
CAS 133232-73-2C16H20BrNO3S
Methyl 5-((((7,7-dimethyl-2-oxobicyclo[2.2.1]heptyl)methyl)sulfonyl)amino)-3-(methoxycarbonyl)benzoate chemical structure, C20H25NO7S, CAS 453582-55-3
Methyl 5-((((7,7-dimethyl-2-oxobicyclo[2.2.1]heptyl)methyl)sulfonyl)amino)-3-(methoxycarbonyl)benzoate
CAS 453582-55-3C20H25NO7S
1-((((3,5-Bis(trifluoromethyl)phenyl)amino)sulfonyl)methyl)-7,7-dimethylbicyclo[2.2.1]heptan-2-one chemical structure, C18H19F6NO3S, CAS 1024414-65-0
1-((((3,5-Bis(trifluoromethyl)phenyl)amino)sulfonyl)methyl)-7,7-dimethylbicyclo[2.2.1]heptan-2-one
CAS 1024414-65-0C18H19F6NO3S
1-(7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)-N-(2-ethylphenyl)methanesulfonamide chemical structure, C18H25NO3S, CAS 7066-39-9
1-(7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)-N-(2-ethylphenyl)methanesulfonamide
CAS 7066-39-9C18H25NO3S
N-(3-Chloro-2-methylphenyl)-1-(7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonamide chemical structure, C17H22ClNO3S, CAS 7066-40-2
N-(3-Chloro-2-methylphenyl)-1-(7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonamide
CAS 7066-40-2C17H22ClNO3S
1-(7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)-N-(2,4,5-trichlorophenyl)methanesulfonamide chemical structure, C16H18Cl3NO3S, CAS 7066-41-3
1-(7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)-N-(2,4,5-trichlorophenyl)methanesulfonamide
CAS 7066-41-3C16H18Cl3NO3S
N-(2,5-Dichlorophenyl)-1-(7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl)methanesulfonamide chemical structure, C16H19Cl2NO3S, CAS 7066-42-4
N-(2,5-Dichlorophenyl)-1-(7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl)methanesulfonamide
CAS 7066-42-4C16H19Cl2NO3S
N-(2,4-Dimethyl-6-nitrophenyl)-1-(7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonamide chemical structure, C18H24N2O5S, CAS 7066-43-5
N-(2,4-Dimethyl-6-nitrophenyl)-1-(7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonamide
CAS 7066-43-5C18H24N2O5S
1-((((2,4-Difluorophenyl)amino)sulfonyl)methyl)-7,7-dimethylbicyclo[2.2.1]heptan-2-one chemical structure, C16H19F2NO3S, CAS 1274903-91-1
1-((((2,4-Difluorophenyl)amino)sulfonyl)methyl)-7,7-dimethylbicyclo[2.2.1]heptan-2-one
CAS 1274903-91-1C16H19F2NO3S
7,7-Dimethyl-1-((((4-(trifluoromethoxy)phenyl)amino)sulfonyl)methyl)bicyclo[2.2.1]heptan-2-one chemical structure, C17H20F3NO4S, CAS 1274903-85-3
7,7-Dimethyl-1-((((4-(trifluoromethoxy)phenyl)amino)sulfonyl)methyl)bicyclo[2.2.1]heptan-2-one
CAS 1274903-85-3C17H20F3NO4S