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Murcko scaffold

Ring system with 3 rings and 15 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
17
With full pages
5
Scaffold SMILES

N=C1NCC=C1c1nc2ccccc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold N=C1NCC=C1c1nc2ccccc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

5-Amino-4-(1H-benzimidazol-2-yl)-1-(2-methoxyethyl)-1,2-dihydro-3H-pyrrol-3-one chemical structure, C14H16N4O2, CAS 749920-79-4
5-Amino-4-(1H-benzimidazol-2-yl)-1-(2-methoxyethyl)-1,2-dihydro-3H-pyrrol-3-one
CAS 749920-79-4C14H16N4O2
5-Amino-4-(1H-benzimidazol-2-yl)-1-sec-butyl-2H-pyrrol-3-one chemical structure, C15H18N4O, CAS 213251-08-2
5-Amino-4-(1H-benzimidazol-2-yl)-1-sec-butyl-2H-pyrrol-3-one
CAS 213251-08-2C15H18N4O
5-Amino-4-(1H-1,3-benzodiazol-2-yl)-1-hexyl-2,3-dihydro-1H-pyrrol-3-one chemical structure, C17H22N4O, CAS 213251-07-1
5-Amino-4-(1H-1,3-benzodiazol-2-yl)-1-hexyl-2,3-dihydro-1H-pyrrol-3-one
CAS 213251-07-1C17H22N4O
5-Amino-4-(1H-1,3-benzodiazol-2-yl)-1-[3-(diethylamino)propyl]-2,3-dihydro-1H-pyrrol-3-one chemical structure, C18H25N5O, CAS 855991-90-1
5-Amino-4-(1H-1,3-benzodiazol-2-yl)-1-[3-(diethylamino)propyl]-2,3-dihydro-1H-pyrrol-3-one
CAS 855991-90-1C18H25N5O
5-Amino-4-(1H-benzimidazol-2-yl)-1-pentyl-2H-pyrrol-3-one chemical structure, C16H20N4O, CAS 150016-23-2
5-Amino-4-(1H-benzimidazol-2-yl)-1-pentyl-2H-pyrrol-3-one
CAS 150016-23-2C16H20N4O
4-(1H-Benzimidazol-2-yl)-1-(3-hydroxypropyl)-5-imino-2,5-dihydro-1H-pyrrol-3-ol chemical structure, C14H16N4O2, CAS 150016-22-1
4-(1H-Benzimidazol-2-yl)-1-(3-hydroxypropyl)-5-imino-2,5-dihydro-1H-pyrrol-3-ol
CAS 150016-22-1C14H16N4O2
5-Amino-4-(1H-benzimidazol-2-yl)-1-(3-methylbutyl)-1,2-dihydro-3H-pyrrol-3-one chemical structure, C16H20N4O, CAS 881044-20-8
5-Amino-4-(1H-benzimidazol-2-yl)-1-(3-methylbutyl)-1,2-dihydro-3H-pyrrol-3-one
CAS 881044-20-8C16H20N4O
5-Amino-4-(1H-benzo[d]imidazol-2-yl)-1-butyl-1H-pyrrol-3(2H)-one chemical structure, C15H18N4O, CAS 459138-06-8
5-Amino-4-(1H-benzo[d]imidazol-2-yl)-1-butyl-1H-pyrrol-3(2H)-one
CAS 459138-06-8C15H18N4O
5-Amino-4-(1H-benzimidazol-2-yl)-1-(heptan-2-yl)-1,2-dihydro-3H-pyrrol-3-one chemical structure, C18H24N4O, CAS 852917-04-5
5-Amino-4-(1H-benzimidazol-2-yl)-1-(heptan-2-yl)-1,2-dihydro-3H-pyrrol-3-one
CAS 852917-04-5C18H24N4O
1,5-Diamino-4-(1H-benzoimidazol-2-yl)-1,2-dihydro-pyrrol-3-one chemical structure, C11H11N5O, CAS 885457-79-4
1,5-Diamino-4-(1H-benzoimidazol-2-yl)-1,2-dihydro-pyrrol-3-one
CAS 885457-79-4C11H11N5O
5-Amino-4-(1H-1,3-benzodiazol-2-yl)-1-(3-methoxypropyl)-2,3-dihydro-1H-pyrrol-3-one chemical structure, C15H18N4O2, CAS 857492-80-9
5-Amino-4-(1H-1,3-benzodiazol-2-yl)-1-(3-methoxypropyl)-2,3-dihydro-1H-pyrrol-3-one
CAS 857492-80-9C15H18N4O2
4-(1H-Benzimidazol-2-yl)-1-(2-hydroxyethyl)-5-imino-2,5-dihydro-1H-pyrrol-3-ol chemical structure, C13H14N4O2, CAS 881045-25-6
4-(1H-Benzimidazol-2-yl)-1-(2-hydroxyethyl)-5-imino-2,5-dihydro-1H-pyrrol-3-ol
CAS 881045-25-6C13H14N4O2
5-Amino-4-(1H-1,3-benzodiazol-2-yl)-1-(3-butoxypropyl)-2,3-dihydro-1H-pyrrol-3-one chemical structure, C18H24N4O2, CAS 857492-83-2
5-Amino-4-(1H-1,3-benzodiazol-2-yl)-1-(3-butoxypropyl)-2,3-dihydro-1H-pyrrol-3-one
CAS 857492-83-2C18H24N4O2
2-[3-(1H-Benzimidazol-2-yl)-4-hydroxy-2-imino-2,5-dihydro-1H-pyrrol-1-yl]-N,N-dimethylethanesulfonamide chemical structure, C15H19N5O3S, CAS 1676055-02-9
2-[3-(1H-Benzimidazol-2-yl)-4-hydroxy-2-imino-2,5-dihydro-1H-pyrrol-1-yl]-N,N-dimethylethanesulfonamide
CAS 1676055-02-9C15H19N5O3S
5-Amino-4-(1H-benzo[d]imidazol-2-yl)-1-heptyl-1H-pyrrol-3(2H)-one chemical structure, C18H24N4O, CAS 881566-98-9
5-Amino-4-(1H-benzo[d]imidazol-2-yl)-1-heptyl-1H-pyrrol-3(2H)-one
CAS 881566-98-9C18H24N4O
5-Amino-4-(1H-1,3-benzodiazol-2-yl)-1-[3-(propan-2-yloxy)propyl]-2,3-dihydro-1H-pyrrol-3-one chemical structure, C17H22N4O2, CAS 881567-33-5
5-Amino-4-(1H-1,3-benzodiazol-2-yl)-1-[3-(propan-2-yloxy)propyl]-2,3-dihydro-1H-pyrrol-3-one
CAS 881567-33-5C17H22N4O2
5-Amino-4-(1H-benzimidazol-2-yl)-1-[2-(diethylamino)ethyl]-1,2-dihydro-3H-pyrrol-3-one chemical structure, C17H23N5O, CAS 880447-59-6
5-Amino-4-(1H-benzimidazol-2-yl)-1-[2-(diethylamino)ethyl]-1,2-dihydro-3H-pyrrol-3-one
CAS 880447-59-6C17H23N5O