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Murcko scaffold

Ring system with 3 rings and 14 atoms

22 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
22
With full pages
1
Scaffold SMILES

c1ccc2[nH]c(-c3cnon3)nc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2[nH]c(-c3cnon3)nc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

4-(5-Methyl-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C10H9N5O, CAS 342789-66-6
4-(5-Methyl-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine
CAS 342789-66-6C10H9N5O
4-(1-Ethyl-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C11H11N5O, CAS 293760-29-9
4-(1-Ethyl-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine
CAS 293760-29-9C11H11N5O
4-(1-Prop-2-ynylbenzimidazol-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C12H9N5O, CAS 328243-88-5
4-(1-Prop-2-ynylbenzimidazol-2-yl)-1,2,5-oxadiazol-3-amine
CAS 328243-88-5C12H9N5O
2-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1H-benzimidazol-1-yl]acetohydrazide chemical structure, C11H11N7O2, CAS 524037-49-8
2-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1H-benzimidazol-1-yl]acetohydrazide
CAS 524037-49-8C11H11N7O2
2-(4-Amino-1,2,5-oxadiazol-3-yl)-N-(1,1-dimethylethyl)-1H-benzimidazole-1-acetamide chemical structure, C15H18N6O2, CAS 384860-19-9
2-(4-Amino-1,2,5-oxadiazol-3-yl)-N-(1,1-dimethylethyl)-1H-benzimidazole-1-acetamide
CAS 384860-19-9C15H18N6O2
4-(1-Isopropyl-1H-benzo[d]imidazol-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C12H13N5O, CAS 296789-97-4
4-(1-Isopropyl-1H-benzo[d]imidazol-2-yl)-1,2,5-oxadiazol-3-amine
CAS 296789-97-4C12H13N5O
4-(1H-Benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C9H7N5O, CAS 332026-86-5
4-(1H-Benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine
CAS 332026-86-5C9H7N5O
4-[1-(3-Methyl-butyl)-1H-benzoimidazol-2-yl]-furazan-3-ylamine chemical structure, C14H17N5O, CAS 5169-63-1
4-[1-(3-Methyl-butyl)-1H-benzoimidazol-2-yl]-furazan-3-ylamine
CAS 5169-63-1C14H17N5O
4-(1-Methyl-1H-benzoimidazol-2-yl)-furazan-3-ylamine chemical structure, C10H9N5O, CAS 332026-41-2
4-(1-Methyl-1H-benzoimidazol-2-yl)-furazan-3-ylamine
CAS 332026-41-2C10H9N5O
Ethyl 2-[2-(4-amino-1,2,5-oxadiazol-3-yl)benzimidazol-1-yl]acetate chemical structure, C13H13N5O3, CAS 332026-91-2
Ethyl 2-[2-(4-amino-1,2,5-oxadiazol-3-yl)benzimidazol-1-yl]acetate
CAS 332026-91-2C13H13N5O3
[2-(4-Amino-furazan-3-yl)-benzoimidazol-1-yl]-acetic acid chemical structure, C11H9N5O3, CAS 296790-01-7
[2-(4-Amino-furazan-3-yl)-benzoimidazol-1-yl]-acetic acid
CAS 296790-01-7C11H9N5O3
Ethyl 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)benzimidazol-1-yl]propanoate chemical structure, C14H15N5O3, CAS 696649-37-3
Ethyl 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)benzimidazol-1-yl]propanoate
CAS 696649-37-3C14H15N5O3
4-(1-Ethyl-5-fluoro-1H-benzimidazol-2-yl)-furazan-3-ylamine chemical structure, C11H10FN5O, CAS 862814-84-4
4-(1-Ethyl-5-fluoro-1H-benzimidazol-2-yl)-furazan-3-ylamine
CAS 862814-84-4C11H10FN5O
4-(7-Chloro-1-methyl-1H-benzo[d]imidazol-2-yl)-1,2,5-oxadiazol-3-amine4-(7-chloro-1-methyl-1H-benzo[d]imidazole-2-yl)-1,2,5-oxadiazole-3-amine chemical structure, C10H8ClN5O, CAS 1281345-62-7
4-(7-Chloro-1-methyl-1H-benzo[d]imidazol-2-yl)-1,2,5-oxadiazol-3-amine4-(7-chloro-1-methyl-1H-benzo[d]imidazole-2-yl)-1,2,5-oxadiazole-3-amine
CAS 1281345-62-7C10H8ClN5O
4-(7-Methyl-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C10H9N5O, CAS 581081-12-1
4-(7-Methyl-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine
CAS 581081-12-1C10H9N5O
4-(5,6-Dichloro-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C9H5Cl2N5O, CAS 581080-96-8
4-(5,6-Dichloro-1H-benzimidazol-2-yl)-1,2,5-oxadiazol-3-amine
CAS 581080-96-8C9H5Cl2N5O
2-(4-Methyl-1,2,5-oxadiazol-3-yl)-1H-benzimidazole chemical structure, C10H8N4O, CAS 1075247-74-3
2-(4-Methyl-1,2,5-oxadiazol-3-yl)-1H-benzimidazole
CAS 1075247-74-3C10H8N4O
4-(7-Fluoro-1H-benzo[d]imidazol-2-yl)-1,2,5-oxadiazol-3-amine chemical structure, C9H6FN5O, CAS 1343321-02-7
4-(7-Fluoro-1H-benzo[d]imidazol-2-yl)-1,2,5-oxadiazol-3-amine
CAS 1343321-02-7C9H6FN5O
2-(4-Amino-1,2,5-oxadiazol-3-yl)-1H-1,3-benzodiazol-5-ol chemical structure, C9H7N5O2, CAS 1511228-91-3
2-(4-Amino-1,2,5-oxadiazol-3-yl)-1H-1,3-benzodiazol-5-ol
CAS 1511228-91-3C9H7N5O2
3-[4-(1H-Benzoimidazol-2-yl)-furazan-3-ylamino]-propionitrile chemical structure, C12H10N6O, CAS 798578-48-0
3-[4-(1H-Benzoimidazol-2-yl)-furazan-3-ylamino]-propionitrile
CAS 798578-48-0C12H10N6O
7-Chloro-2-(4-methyl-1,2,5-oxadiazol-3-yl)-1H-benzimidazole chemical structure, C10H7ClN4O, CAS 2612692-66-5
7-Chloro-2-(4-methyl-1,2,5-oxadiazol-3-yl)-1H-benzimidazole
CAS 2612692-66-5C10H7ClN4O
tert-Butyl N-[4-(5-hydroxy-1H-1,3-benzodiazol-2-yl)-1,2,5-oxadiazol-3-yl]carbamate chemical structure, C14H15N5O4, CAS 2413870-33-2
tert-Butyl N-[4-(5-hydroxy-1H-1,3-benzodiazol-2-yl)-1,2,5-oxadiazol-3-yl]carbamate
CAS 2413870-33-2C14H15N5O4