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Murcko scaffold

[4-(2-Oxo(3-hydrobenzimidazolyl))piperidyl]-N-benzamide scaffold

18 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
18
With full pages
4
Scaffold SMILES

O=C(Nc1ccccc1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the [4-(2-Oxo(3-hydrobenzimidazolyl))piperidyl]-N-benzamide page
Murcko scaffold O=C(Nc1ccccc1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(3-methoxy-phenyl)piperidin-1-carboxamide chemical structure, C20H22N4O3, CAS 290837-69-3
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(3-methoxy-phenyl)piperidin-1-carboxamide
CAS 290837-69-3C20H22N4O3
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(4-methoxy-phenyl)piperidin-1-carboxamide chemical structure, C20H22N4O3, CAS 290837-70-6
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(4-methoxy-phenyl)piperidin-1-carboxamide
CAS 290837-70-6C20H22N4O3
[4-(2-Oxo(3-hydrobenzimidazolyl))piperidyl]-N-benzamide chemical structure, C19H20N4O2, CAS 891021-55-9
[4-(2-Oxo(3-hydrobenzimidazolyl))piperidyl]-N-benzamide
CAS 891021-55-9C19H20N4O2
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(2-methoxy-phenyl)piperidin-1-carboxamide chemical structure, C20H22N4O3, CAS 290837-68-2
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(2-methoxy-phenyl)piperidin-1-carboxamide
CAS 290837-68-2C20H22N4O3
N-(2,6-Dimethylphenyl)-4-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)piperidine-1-carboxamide chemical structure, C21H24N4O2, CAS 891021-71-9
N-(2,6-Dimethylphenyl)-4-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)piperidine-1-carboxamide
CAS 891021-71-9C21H24N4O2
N-(3-Fluorophenyl)-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1-carboxamide chemical structure, C19H19FN4O2, CAS 290837-64-8
N-(3-Fluorophenyl)-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1-carboxamide
CAS 290837-64-8C19H19FN4O2
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(2-methylphenyl)piperidin-1-carboxamide chemical structure, C20H22N4O2, CAS 442688-13-3
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(2-methylphenyl)piperidin-1-carboxamide
CAS 442688-13-3C20H22N4O2
N-(4-Fluorophenyl)[4-(2-oxo(3-hydrobenzimidazolyl))piperidyl]carboxamide chemical structure, C19H19FN4O2, CAS 891022-67-6
N-(4-Fluorophenyl)[4-(2-oxo(3-hydrobenzimidazolyl))piperidyl]carboxamide
CAS 891022-67-6C19H19FN4O2
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(3,5-dimethylphenyl)piperidin-1-carboxamide chemical structure, C21H24N4O2, CAS 1135731-60-0
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(3,5-dimethylphenyl)piperidin-1-carboxamide
CAS 1135731-60-0C21H24N4O2
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(3-fluoro-4-methylphenyl)piperidin-1-carboxamide chemical structure, C20H21FN4O2, CAS 1177759-70-4
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(3-fluoro-4-methylphenyl)piperidin-1-carboxamide
CAS 1177759-70-4C20H21FN4O2
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(2,5-dimethylphenyl)piperidin-1-carboxamide chemical structure, C21H24N4O2, CAS 1177973-92-0
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(2,5-dimethylphenyl)piperidin-1-carboxamide
CAS 1177973-92-0C21H24N4O2
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(3-ethylphenyl)piperidin-1-carboxamide chemical structure, C21H24N4O2, CAS 1136429-60-1
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(3-ethylphenyl)piperidin-1-carboxamide
CAS 1136429-60-1C21H24N4O2
N-(3-Cyanophenyl)-4-(2,3-dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)piperidin-1-carboxamide chemical structure, C20H19N5O2, CAS 909682-25-3
N-(3-Cyanophenyl)-4-(2,3-dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)piperidin-1-carboxamide
CAS 909682-25-3C20H19N5O2
N-(4-Chlorophenyl)[4-(2-oxo(3-hydrobenzimidazolyl))piperidyl]carboxamide chemical structure, C19H19ClN4O2, CAS 943426-54-8
N-(4-Chlorophenyl)[4-(2-oxo(3-hydrobenzimidazolyl))piperidyl]carboxamide
CAS 943426-54-8C19H19ClN4O2
N-(3-Chlorophenyl)[4-(2-oxo(3-hydrobenzimidazolyl))piperidyl]carboxamide chemical structure, C19H19ClN4O2, CAS 943410-21-7
N-(3-Chlorophenyl)[4-(2-oxo(3-hydrobenzimidazolyl))piperidyl]carboxamide
CAS 943410-21-7C19H19ClN4O2
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(4-methylphenyl)piperidin-1-carboxamide chemical structure, C20H22N4O2, CAS 891017-37-1
4-(2,3-Dihydro-2-oxo-1H-benzo[d]imidazol-1-yl)-N-(4-methylphenyl)piperidin-1-carboxamide
CAS 891017-37-1C20H22N4O2
RefChem:188995 chemical structure, C19H18BrIN4O2, CAS 2304947-71-3
RefChem:188995
CAS 2304947-71-3C19H18BrIN4O2
4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-phenylpiperidine-1-carboxamide chemical structure, C19H19ClN4O2, CAS 3032753-75-3
4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-phenylpiperidine-1-carboxamide
CAS 3032753-75-3C19H19ClN4O2