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Murcko scaffold

Ring system with 4 rings and 23 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
8
With full pages
1
Scaffold SMILES

O=C(c1ccccc1)c1cn(-c2ccccc2)c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1cn(-c2ccccc2)c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

[5-Hydroxy-2-methyl-1-(4-methylphenyl)indol-3-yl]-phenylmethanone chemical structure, C23H19NO2, CAS 159112-28-4
[5-Hydroxy-2-methyl-1-(4-methylphenyl)indol-3-yl]-phenylmethanone
CAS 159112-28-4C23H19NO2
[1-(4-Ethoxyphenyl)-5-hydroxy-2-methylindol-3-yl]-phenylmethanone chemical structure, C24H21NO3, CAS 326612-22-0
[1-(4-Ethoxyphenyl)-5-hydroxy-2-methylindol-3-yl]-phenylmethanone
CAS 326612-22-0C24H21NO3
[5-Hydroxy-1-(4-iodophenyl)-2-methylindol-3-yl]-phenylmethanone chemical structure, C22H16INO2, CAS 332017-55-7
[5-Hydroxy-1-(4-iodophenyl)-2-methylindol-3-yl]-phenylmethanone
CAS 332017-55-7C22H16INO2
Ethyl 2-[3-benzoyl-1-(4-methoxyphenyl)-2-methylindol-5-yl]oxyacetate chemical structure, C27H25NO5, CAS 380645-13-6
Ethyl 2-[3-benzoyl-1-(4-methoxyphenyl)-2-methylindol-5-yl]oxyacetate
CAS 380645-13-6C27H25NO5
[5-Hydroxy-1-(4-methoxyphenyl)-2-methylindol-3-yl]-phenylmethanone chemical structure, C23H19NO3, CAS 159112-27-3
[5-Hydroxy-1-(4-methoxyphenyl)-2-methylindol-3-yl]-phenylmethanone
CAS 159112-27-3C23H19NO3
MK-0533 dihydrate chemical structure, C28H28F3NO8, CAS 910378-55-1
MK-0533 dihydrate
CAS 910378-55-1C28H28F3NO8
Mk-0533 chemical structure, C28H24F3NO6, CAS 668455-28-5
Mk-0533
CAS 668455-28-5C28H24F3NO6
(2R)-2-(3-(3-(4-Methoxybenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl)phenoxy)butanoic acid sodium salt chemical structure, C28H23F3NNaO6, CAS 668458-85-3
(2R)-2-(3-(3-(4-Methoxybenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl)phenoxy)butanoic acid sodium salt
CAS 668458-85-3C28H23F3NNaO6