Murcko scaffold
2-(3-Oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)-N-phenylacetamide scaffold
15 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 25
- Chemicals
- 15
- With full pages
- 6
Scaffold SMILES
O=C(CC1Nc2cccc3cccc(c23)NC1=O)Nc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 15 of 15 chemicals
![N-(4-Methoxyphenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide chemical structure, C21H19N3O3, CAS 1008640-08-1](/s/BQQIHAGUYKMXAT-UHFFFAOYSA-N.svg)
N-(4-Methoxyphenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide
CAS 1008640-08-1C21H19N3O3
![N-(4-Nitrophenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide chemical structure, C20H16N4O4, CAS 1008979-89-2](/s/ISKHDGHPBCTELY-UHFFFAOYSA-N.svg)
N-(4-Nitrophenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide
CAS 1008979-89-2C20H16N4O4
![N-[4-(Difluoromethoxy)phenyl]-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide chemical structure, C21H17F2N3O3, CAS 1009520-38-0](/s/WJWSRKRPSHRAMH-UHFFFAOYSA-N.svg)
N-[4-(Difluoromethoxy)phenyl]-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide
CAS 1009520-38-0C21H17F2N3O3
![Ethyl 4-{[(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetyl]amino}benzoate chemical structure, C23H21N3O4, CAS 1009278-41-4](/s/BOSOHOVKQGPRLG-UHFFFAOYSA-N.svg)
Ethyl 4-{[(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetyl]amino}benzoate
CAS 1009278-41-4C23H21N3O4
![N-(3-Methylphenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide chemical structure, C21H19N3O2, CAS 1009505-68-3](/s/YWQBWYXHFQVQRQ-UHFFFAOYSA-N.svg)
N-(3-Methylphenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide
CAS 1009505-68-3C21H19N3O2
![N-(3-Nitrophenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide chemical structure, C20H16N4O4, CAS 1009278-42-5](/s/GXWFDGFJGOZXQP-UHFFFAOYSA-N.svg)
N-(3-Nitrophenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide
CAS 1009278-42-5C20H16N4O4
![2-(3-Oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)-N-phenylacetamide chemical structure, C20H17N3O2, CAS 1008201-43-1](/s/BHTGFUWVWVMWPV-UHFFFAOYSA-N.svg)
2-(3-Oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)-N-phenylacetamide
CAS 1008201-43-1C20H17N3O2
![N-(4-Chlorophenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide chemical structure, C20H16ClN3O2, CAS 1009733-09-8](/s/KVRYHXDXCYUZIK-UHFFFAOYSA-N.svg)
N-(4-Chlorophenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide
CAS 1009733-09-8C20H16ClN3O2
![2-(3-Oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)-N-(3-(trifluoromethyl)phenyl)acetamide chemical structure, C21H16F3N3O2, CAS 1008011-97-9](/s/XBMNHCBYPLLHTB-UHFFFAOYSA-N.svg)
2-(3-Oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)-N-(3-(trifluoromethyl)phenyl)acetamide
CAS 1008011-97-9C21H16F3N3O2
![N-(2-Fluorophenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide chemical structure, C20H16FN3O2, CAS 1008011-95-7](/s/GTIQZMROORFMBQ-UHFFFAOYSA-N.svg)
N-(2-Fluorophenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide
CAS 1008011-95-7C20H16FN3O2
![N-(2-Chlorophenyl)-2-(3-hydroxy-1,2-dihydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide chemical structure, C20H16ClN3O2, CAS 1008011-94-6](/s/RZSRYBRCIUQRMA-UHFFFAOYSA-N.svg)
N-(2-Chlorophenyl)-2-(3-hydroxy-1,2-dihydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide
CAS 1008011-94-6C20H16ClN3O2
![Methyl 2-{[(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetyl]amino}benzoate chemical structure, C22H19N3O4, CAS 1008011-96-8](/s/FJZPFBFQGSXYHW-UHFFFAOYSA-N.svg)
Methyl 2-{[(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetyl]amino}benzoate
CAS 1008011-96-8C22H19N3O4
![N-[4-(Acetylamino)phenyl]-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide chemical structure, C22H20N4O3, CAS 1008038-80-9](/s/QJFUPNCWTKRSMK-UHFFFAOYSA-N.svg)
N-[4-(Acetylamino)phenyl]-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide
CAS 1008038-80-9C22H20N4O3
![N-(4-Ethoxyphenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide chemical structure, C22H21N3O3, CAS 1009672-77-8](/s/UFVAJRKNCQXGGR-UHFFFAOYSA-N.svg)
N-(4-Ethoxyphenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide
CAS 1009672-77-8C22H21N3O3
![N-(4-Methylphenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide chemical structure, C21H19N3O2, CAS 1008243-86-4](/s/ZCCFUXAIIKQGDE-UHFFFAOYSA-N.svg)
N-(4-Methylphenyl)-2-(3-oxo-1,2,3,4-tetrahydronaphtho[1,8-ef][1,4]diazepin-2-yl)acetamide
CAS 1008243-86-4C21H19N3O2