Murcko scaffold
Ring system with 2 rings and 15 atoms
21 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 15
- Chemicals
- 21
- With full pages
- 3
Scaffold SMILES
O=C(Sc1cccnc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 21 of 21 chemicals
![3-[(3-Chlorobenzoyl)sulfanyl]pyridine-2-carboxylic acid chemical structure, C13H8ClNO3S, CAS 62013-46-1](/s/OGJQAFPKORMTFI-UHFFFAOYSA-N.svg)
3-[(3-Chlorobenzoyl)sulfanyl]pyridine-2-carboxylic acid
CAS 62013-46-1C13H8ClNO3S
![3-[(2-Chlorobenzoyl)sulfanyl]pyridine-2-carboxylic acid chemical structure, C13H8ClNO3S, CAS 62042-52-8](/s/ODJKXAPYULALAU-UHFFFAOYSA-N.svg)
3-[(2-Chlorobenzoyl)sulfanyl]pyridine-2-carboxylic acid
CAS 62042-52-8C13H8ClNO3S
![3-[(4-Chlorobenzoyl)sulfanyl]pyridine-2-carboxylic acid chemical structure, C13H8ClNO3S, CAS 62013-59-6](/s/YYQSANCFEBTTRI-UHFFFAOYSA-N.svg)
3-[(4-Chlorobenzoyl)sulfanyl]pyridine-2-carboxylic acid
CAS 62013-59-6C13H8ClNO3S
![3-{[3-(Trifluoromethyl)benzoyl]sulfanyl}pyridine-2-carboxylic acid chemical structure, C14H8F3NO3S, CAS 62042-53-9](/s/SILSZUXOCFMOPI-UHFFFAOYSA-N.svg)
3-{[3-(Trifluoromethyl)benzoyl]sulfanyl}pyridine-2-carboxylic acid
CAS 62042-53-9C14H8F3NO3S
![3-{[4-(Trifluoromethyl)benzoyl]sulfanyl}pyridine-2-carboxylic acid chemical structure, C14H8F3NO3S, CAS 62013-60-9](/s/NHXPCEPTRLECGI-UHFFFAOYSA-N.svg)
3-{[4-(Trifluoromethyl)benzoyl]sulfanyl}pyridine-2-carboxylic acid
CAS 62013-60-9C14H8F3NO3S
![3-[(3-Methoxybenzoyl)sulfanyl]pyridine-2-carboxylic acid chemical structure, C14H11NO4S, CAS 62013-47-2](/s/YPBPFIZQWDAWAZ-UHFFFAOYSA-N.svg)
3-[(3-Methoxybenzoyl)sulfanyl]pyridine-2-carboxylic acid
CAS 62013-47-2C14H11NO4S
![3-[(4-Methoxybenzoyl)sulfanyl]pyridine-2-carboxylic acid chemical structure, C14H11NO4S, CAS 62013-48-3](/s/PJJGEVDSAJZJHT-UHFFFAOYSA-N.svg)
3-[(4-Methoxybenzoyl)sulfanyl]pyridine-2-carboxylic acid
CAS 62013-48-3C14H11NO4S
![3-[(4-Methylbenzoyl)sulfanyl]pyridine-2-carboxylic acid chemical structure, C14H11NO3S, CAS 62013-49-4](/s/VPNQTTSQIIQXJE-UHFFFAOYSA-N.svg)
3-[(4-Methylbenzoyl)sulfanyl]pyridine-2-carboxylic acid
CAS 62013-49-4C14H11NO3S
![3-[(4-Fluorobenzoyl)sulfanyl]pyridine-2-carboxylic acid chemical structure, C13H8FNO3S, CAS 62013-50-7](/s/CDHXLGHNCIKKBY-UHFFFAOYSA-N.svg)
3-[(4-Fluorobenzoyl)sulfanyl]pyridine-2-carboxylic acid
CAS 62013-50-7C13H8FNO3S
![3-[(4-Nitrobenzoyl)sulfanyl]pyridine-2-carboxylic acid chemical structure, C13H8N2O5S, CAS 62013-51-8](/s/NZLDHPPPENMQDZ-UHFFFAOYSA-N.svg)
3-[(4-Nitrobenzoyl)sulfanyl]pyridine-2-carboxylic acid
CAS 62013-51-8C13H8N2O5S
![3-[(4-Cyanobenzoyl)sulfanyl]pyridine-2-carboxylic acid chemical structure, C14H8N2O3S, CAS 62013-52-9](/s/PSUZEFPNWMNOQF-UHFFFAOYSA-N.svg)
3-[(4-Cyanobenzoyl)sulfanyl]pyridine-2-carboxylic acid
CAS 62013-52-9C14H8N2O3S
![3-{[4-(Methoxycarbonyl)benzoyl]sulfanyl}pyridine-2-carboxylic acid chemical structure, C15H11NO5S, CAS 62013-53-0](/s/BDODLTHAFJCFFY-UHFFFAOYSA-N.svg)
3-{[4-(Methoxycarbonyl)benzoyl]sulfanyl}pyridine-2-carboxylic acid
CAS 62013-53-0C15H11NO5S
![3-[(4-Sulfamoylbenzoyl)sulfanyl]pyridine-2-carboxylic acid chemical structure, C13H10N2O5S2, CAS 62013-54-1](/s/RUNSRMGNOWKBME-UHFFFAOYSA-N.svg)
3-[(4-Sulfamoylbenzoyl)sulfanyl]pyridine-2-carboxylic acid
CAS 62013-54-1C13H10N2O5S2
![3-[(4-Carbamoylbenzoyl)sulfanyl]pyridine-2-carboxylic acid chemical structure, C14H10N2O4S, CAS 62013-55-2](/s/OEMGEUVAMHWYTM-UHFFFAOYSA-N.svg)
3-[(4-Carbamoylbenzoyl)sulfanyl]pyridine-2-carboxylic acid
CAS 62013-55-2C14H10N2O4S
![3-[(4-Acetamidobenzoyl)sulfanyl]pyridine-2-carboxylic acid chemical structure, C15H12N2O4S, CAS 62013-56-3](/s/QLMRZSQDLJSDMW-UHFFFAOYSA-N.svg)
3-[(4-Acetamidobenzoyl)sulfanyl]pyridine-2-carboxylic acid
CAS 62013-56-3C15H12N2O4S
![3-{[4-(Dimethylamino)benzoyl]sulfanyl}pyridine-2-carboxylic acid chemical structure, C15H14N2O3S, CAS 62013-58-5](/s/OMQFDRSPXYTHJR-UHFFFAOYSA-N.svg)
3-{[4-(Dimethylamino)benzoyl]sulfanyl}pyridine-2-carboxylic acid
CAS 62013-58-5C15H14N2O3S
methanone chemical structure, C12H8ClNOS, CAS 1383948-70-6](/s/FTFFHKYHQCOBNB-UHFFFAOYSA-N.svg)
[(6-Chloropyridin-3-yl)sulfanyl](phenyl)methanone
CAS 1383948-70-6C12H8ClNOS
methanone chemical structure, C12H8FNOS, CAS 2648955-92-2](/s/OWNVRDZVXTUNNZ-UHFFFAOYSA-N.svg)
[(2-Fluoropyridin-3-yl)sulfanyl](phenyl)methanone
CAS 2648955-92-2C12H8FNOS
methanone chemical structure, C13H11NO2S, CAS 2624138-61-8](/s/VHAKVTPWUZWYCY-UHFFFAOYSA-N.svg)
[(2-Methoxypyridin-3-yl)sulfanyl](phenyl)methanone
CAS 2624138-61-8C13H11NO2S
methanone chemical structure, C13H11NOS, CAS 2680543-05-7](/s/XVGQAAQJDJPRQL-UHFFFAOYSA-N.svg)
[(4-Methylpyridin-3-yl)sulfanyl](phenyl)methanone
CAS 2680543-05-7C13H11NOS
methanone chemical structure, C14H13NOS, CAS 2680543-38-6](/s/NUWOGJJGDCNESD-UHFFFAOYSA-N.svg)
[(2,6-Dimethylpyridin-3-yl)sulfanyl](phenyl)methanone
CAS 2680543-38-6C14H13NOS
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccccc11,973 chemicals
O=S(=O)(Nc1ccccc1)c1ccccc1978 chemicals
c1ccc(COc2ccccc2)cc1829 chemicals
c1ccc(N=Nc2ccccc2)cc1383 chemicals
C(=Nc1ccccc1)c1ccccc1379 chemicals
O=C(Oc1ccccc1)c1ccccc1309 chemicals
c1ccc(CNc2ccccc2)cc1309 chemicals
C(=Cc1ccccc1)c1ccccc1279 chemicals
c1ccc(CCc2ccccc2)cc1264 chemicals
O=C(Nc1ccccc1)c1cccnc1140 chemicals
O=C(Cc1ccccc1)c1ccccc1137 chemicals
O=C(Nc1ccccn1)c1ccccc1120 chemicals