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Murcko scaffold

6,7-Dihydro-5H-cyclopenta(d)pyrimidine scaffold

150 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
150
With full pages
16
Scaffold SMILES

c1ncc2c(n1)CCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6,7-Dihydro-5H-cyclopenta(d)pyrimidine page
Murcko scaffold c1ncc2c(n1)CCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 150 chemicals

2-Methyl-5,6-cyclopentapyrimidine chemical structure, C8H10N2, CAS 36274-29-0
2-Methyl-5,6-cyclopentapyrimidine
CAS 36274-29-0C8H10N2
4-Chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-amine chemical structure, C7H8ClN3, CAS 5461-89-2
4-Chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-amine
CAS 5461-89-2C7H8ClN3
6,7-Dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine chemical structure, C7H10N4, CAS 1899-39-4
6,7-Dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine
CAS 1899-39-4C7H10N4
4-Methoxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-amine chemical structure, C8H11N3O, CAS 61539-20-6
4-Methoxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-amine
CAS 61539-20-6C8H11N3O
4-N,4-N-diethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine chemical structure, C11H18N4, CAS 5466-02-4
4-N,4-N-diethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine
CAS 5466-02-4C11H18N4
2,4-Dichloro-5H,6H,7H-cyclopenta(d)pyrimidine chemical structure, C7H6Cl2N2, CAS 5466-43-3
2,4-Dichloro-5H,6H,7H-cyclopenta(d)pyrimidine
CAS 5466-43-3C7H6Cl2N2
4-(Methylsulfanyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-amine chemical structure, C8H11N3S, CAS 7511-83-3
4-(Methylsulfanyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-amine
CAS 7511-83-3C8H11N3S
5H,6H,7H-Cyclopenta(d)pyrimidin-2-amine chemical structure, C7H9N3, CAS 108990-72-3
5H,6H,7H-Cyclopenta(d)pyrimidin-2-amine
CAS 108990-72-3C7H9N3
4-Chloro-2-(methylthio)-6,7-dihydro-5H-cyclopenta[d]pyrimidine chemical structure, C8H9ClN2S, CAS 51660-15-2
4-Chloro-2-(methylthio)-6,7-dihydro-5H-cyclopenta[d]pyrimidine
CAS 51660-15-2C8H9ClN2S
RefChem:267495 chemical structure, C7H9N3, CAS 26979-06-6
RefChem:267495
CAS 26979-06-6C7H9N3
n4-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine chemical structure, C8H12N4, CAS 5472-65-1
n4-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine
CAS 5472-65-1C8H12N4
4-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine chemical structure, C8H10N2, CAS 500893-45-8
4-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine
CAS 500893-45-8C8H10N2
4-Chloro-2-methyl-5H,6H,7H-cyclopenta(d)pyrimidine chemical structure, C8H9ClN2, CAS 118802-40-7
4-Chloro-2-methyl-5H,6H,7H-cyclopenta(d)pyrimidine
CAS 118802-40-7C8H9ClN2
2-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine chemical structure, C8H11N3, CAS 69390-17-6
2-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine
CAS 69390-17-6C8H11N3
2-(5-Aminopentyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine chemical structure, C12H20N4, CAS 21543-30-6
2-(5-Aminopentyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine
CAS 21543-30-6C12H20N4
4-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-amine chemical structure, C8H11N3, CAS 76881-49-7
4-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-amine
CAS 76881-49-7C8H11N3
4-Methyl-N,N-dipropyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-amine chemical structure, C14H23N3, CAS 343374-35-6
4-Methyl-N,N-dipropyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-amine
CAS 343374-35-6C14H23N3
Ethyl 2-[(4-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-yl)sulfonyl]acetate chemical structure, C12H16N2O4S, CAS 339019-64-6
Ethyl 2-[(4-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-yl)sulfonyl]acetate
CAS 339019-64-6C12H16N2O4S
(2-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)hydrazine chemical structure, C8H12N4, CAS 879641-59-5
(2-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)hydrazine
CAS 879641-59-5C8H12N4
2-Chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine chemical structure, C7H8ClN3, CAS 76780-97-7
2-Chloro-5H,6H,7H-cyclopenta[d]pyrimidin-4-amine
CAS 76780-97-7C7H8ClN3
2,4-Di(trimethylsilyloxy)-6,7-dihydro-5H-cyclopenta[d]pyrimidine chemical structure, C13H24N2O2Si2, CAS 59282-54-1
2,4-Di(trimethylsilyloxy)-6,7-dihydro-5H-cyclopenta[d]pyrimidine
CAS 59282-54-1C13H24N2O2Si2
6,7-Dihydro-5H-cyclopenta(d)pyrimidine chemical structure, C7H8N2, CAS 5661-00-7
6,7-Dihydro-5H-cyclopenta(d)pyrimidine
CAS 5661-00-7C7H8N2
2-Chloro-N-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine chemical structure, C8H10ClN3, CAS 76780-98-8
2-Chloro-N-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine
CAS 76780-98-8C8H10ClN3
2-Chloro-4-methoxy-6,7-dihydro-5H-cyclopenta[d]pyrimidine chemical structure, C8H9ClN2O, CAS 81532-47-0
2-Chloro-4-methoxy-6,7-dihydro-5H-cyclopenta[d]pyrimidine
CAS 81532-47-0C8H9ClN2O