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Murcko scaffold

6-Cyclopropyl-2,3-dihydro-1,4-benzodioxine scaffold

72 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
72
With full pages
4
Scaffold SMILES

c1cc2c(cc1C1CC1)OCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Cyclopropyl-2,3-dihydro-1,4-benzodioxine page
Murcko scaffold c1cc2c(cc1C1CC1)OCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 72 of 72 chemicals

2,2-Difluoro-1-(8-methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropan-1-amine chemical structure, C12H13F2NO3, CAS 2228180-33-2
2,2-Difluoro-1-(8-methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropan-1-amine
CAS 2228180-33-2C12H13F2NO3
1-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropane-1-carbaldehyde chemical structure, C12H11BrO3, CAS 2228800-62-0
1-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropane-1-carbaldehyde
CAS 2228800-62-0C12H11BrO3
1-[1-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropyl]methanamine chemical structure, C12H14BrNO2, CAS 2228200-11-9
1-[1-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropyl]methanamine
CAS 2228200-11-9C12H14BrNO2
1-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropan-1-ol chemical structure, C11H11BrO3, CAS 2228651-06-5
1-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropan-1-ol
CAS 2228651-06-5C11H11BrO3
5-Bromo-7-(1-ethynylcyclopropyl)-2,3-dihydro-1,4-benzodioxine chemical structure, C13H11BrO2, CAS 2229072-92-6
5-Bromo-7-(1-ethynylcyclopropyl)-2,3-dihydro-1,4-benzodioxine
CAS 2229072-92-6C13H11BrO2
7-(1-Ethynylcyclopropyl)-5-methoxy-2,3-dihydro-1,4-benzodioxine chemical structure, C14H14O3, CAS 2229102-99-0
7-(1-Ethynylcyclopropyl)-5-methoxy-2,3-dihydro-1,4-benzodioxine
CAS 2229102-99-0C14H14O3
1-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)-N-methylcyclopropan-1-amine chemical structure, C12H14BrNO2, CAS 2229376-08-1
1-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)-N-methylcyclopropan-1-amine
CAS 2229376-08-1C12H14BrNO2
[1-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropyl]methanol chemical structure, C12H13BrO3, CAS 2228201-30-5
[1-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropyl]methanol
CAS 2228201-30-5C12H13BrO3
1-[1-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropyl]methanamine chemical structure, C13H17NO3, CAS 2229387-88-4
1-[1-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropyl]methanamine
CAS 2229387-88-4C13H17NO3
6-(1-Ethynylcyclopropyl)-2,3-dihydro-1,4-benzodioxine chemical structure, C13H12O2, CAS 2228213-60-1
6-(1-Ethynylcyclopropyl)-2,3-dihydro-1,4-benzodioxine
CAS 2228213-60-1C13H12O2
1-[1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,2-dimethylcyclopropyl]methanamine chemical structure, C14H19NO2, CAS 2106661-45-2
1-[1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,2-dimethylcyclopropyl]methanamine
CAS 2106661-45-2C14H19NO2
rac-1-[(1R,2R)-2-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropyl]methanamine chemical structure, C13H17NO3, CAS 2227713-95-1
rac-1-[(1R,2R)-2-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropyl]methanamine
CAS 2227713-95-1C13H17NO3
1-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropan-1-ol chemical structure, C12H14O4, CAS 2229564-88-7
1-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropan-1-ol
CAS 2229564-88-7C12H14O4
1-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropan-1-amine chemical structure, C11H12BrNO2, CAS 2228965-26-0
1-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropan-1-amine
CAS 2228965-26-0C11H12BrNO2
1-[1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,2-difluorocyclopropyl]methanamine chemical structure, C12H13F2NO2, CAS 2229181-50-2
1-[1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,2-difluorocyclopropyl]methanamine
CAS 2229181-50-2C12H13F2NO2
rac-(1R,2S)-2-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropan-1-amine chemical structure, C12H15NO3, CAS 2227873-16-5
rac-(1R,2S)-2-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropan-1-amine
CAS 2227873-16-5C12H15NO3
1-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)-N-methylcyclopropan-1-amine chemical structure, C13H17NO3, CAS 2228513-98-0
1-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)-N-methylcyclopropan-1-amine
CAS 2228513-98-0C13H17NO3
rac-(1R,2S)-2-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropan-1-amine chemical structure, C11H12BrNO2, CAS 2227893-05-0
rac-(1R,2S)-2-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropan-1-amine
CAS 2227893-05-0C11H12BrNO2
[1-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropyl]methanol chemical structure, C13H16O4, CAS 2229501-51-1
[1-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropyl]methanol
CAS 2229501-51-1C13H16O4
1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,2-difluorocyclopropan-1-amine chemical structure, C11H11F2NO2, CAS 2228834-35-1
1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,2-difluorocyclopropan-1-amine
CAS 2228834-35-1C11H11F2NO2
rac-1-[(1R,2R)-2-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropyl]methanamine chemical structure, C12H14BrNO2, CAS 2227812-42-0
rac-1-[(1R,2R)-2-(8-Bromo-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropyl]methanamine
CAS 2227812-42-0C12H14BrNO2
1-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropane-1-carbonitrile chemical structure, C13H13NO3, CAS 2228372-33-4
1-(8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)cyclopropane-1-carbonitrile
CAS 2228372-33-4C13H13NO3
rac-(1R,3S)-3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,2-dimethylcyclopropan-1-amine chemical structure, C13H17NO2, CAS 2227859-10-9
rac-(1R,3S)-3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,2-dimethylcyclopropan-1-amine
CAS 2227859-10-9C13H17NO2
rac-1-[(1R,3R)-3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,2-dimethylcyclopropyl]methanamine chemical structure, C14H19NO2, CAS 2227872-84-4
rac-1-[(1R,3R)-3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2,2-dimethylcyclopropyl]methanamine
CAS 2227872-84-4C14H19NO2