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Murcko scaffold

Ring system with 2 rings and 11 atoms

24 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
24
With full pages
4
Scaffold SMILES

c1cnc(C2CCOC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cnc(C2CCOC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

4-Chloro-2-(oxolan-3-yl)pyrimidine chemical structure, C8H9ClN2O, CAS 1159814-17-1
4-Chloro-2-(oxolan-3-yl)pyrimidine
CAS 1159814-17-1C8H9ClN2O
4-Amino-2-(tetrahydrofuran-3-yl)pyrimidine chemical structure, C8H11N3O, CAS 1159814-20-6
4-Amino-2-(tetrahydrofuran-3-yl)pyrimidine
CAS 1159814-20-6C8H11N3O
2-[2-(Oxolan-3-yl)pyrimidin-5-yl]ethan-1-amine chemical structure, C10H15N3O, CAS 944899-50-7
2-[2-(Oxolan-3-yl)pyrimidin-5-yl]ethan-1-amine
CAS 944899-50-7C10H15N3O
2-(Oxolan-3-yl)pyrimidin-5-amine chemical structure, C8H11N3O, CAS 1247141-42-9
2-(Oxolan-3-yl)pyrimidin-5-amine
CAS 1247141-42-9C8H11N3O
4-Chloro-6-methyl-2-(oxolan-3-yl)pyrimidine chemical structure, C9H11ClN2O, CAS 1251226-29-5
4-Chloro-6-methyl-2-(oxolan-3-yl)pyrimidine
CAS 1251226-29-5C9H11ClN2O
4-Chloro-6-ethyl-2-(oxolan-3-yl)pyrimidine chemical structure, C10H13ClN2O, CAS 1249021-41-7
4-Chloro-6-ethyl-2-(oxolan-3-yl)pyrimidine
CAS 1249021-41-7C10H13ClN2O
4-Chloro-6-(methoxymethyl)-2-(oxolan-3-yl)pyrimidine chemical structure, C10H13ClN2O2, CAS 1249696-17-0
4-Chloro-6-(methoxymethyl)-2-(oxolan-3-yl)pyrimidine
CAS 1249696-17-0C10H13ClN2O2
4,6-Dichloro-2-(tetrahydrofuran-3-yl)pyrimidine chemical structure, C8H8Cl2N2O, CAS 1341502-86-0
4,6-Dichloro-2-(tetrahydrofuran-3-yl)pyrimidine
CAS 1341502-86-0C8H8Cl2N2O
2-(Oxolan-3-yl)pyrimidine-4-carboxylic acid chemical structure, C9H10N2O3, CAS 1489849-46-8
2-(Oxolan-3-yl)pyrimidine-4-carboxylic acid
CAS 1489849-46-8C9H10N2O3
4-Methyl-2-(oxolan-3-yl)pyrimidine-5-carboxylic acid chemical structure, C10H12N2O3, CAS 1468954-20-2
4-Methyl-2-(oxolan-3-yl)pyrimidine-5-carboxylic acid
CAS 1468954-20-2C10H12N2O3
4-Ethyl-2-(tetrahydrofuran-3-yl)pyrimidine-5-carboxylic acid chemical structure, C11H14N2O3, CAS 1468608-72-1
4-Ethyl-2-(tetrahydrofuran-3-yl)pyrimidine-5-carboxylic acid
CAS 1468608-72-1C11H14N2O3
4-Chloro-5-fluoro-6-methyl-2-(oxolan-3-yl)pyrimidine chemical structure, C9H10ClFN2O, CAS 1483920-55-3
4-Chloro-5-fluoro-6-methyl-2-(oxolan-3-yl)pyrimidine
CAS 1483920-55-3C9H10ClFN2O
3-(5-Bromopyrimidin-2-yl)oxolan-3-ol chemical structure, C8H9BrN2O2, CAS 1536397-85-9
3-(5-Bromopyrimidin-2-yl)oxolan-3-ol
CAS 1536397-85-9C8H9BrN2O2
3-(5-Bromopyrimidin-2-yl)oxolan-3-amine chemical structure, C8H10BrN3O, CAS 1864255-95-7
3-(5-Bromopyrimidin-2-yl)oxolan-3-amine
CAS 1864255-95-7C8H10BrN3O
5-Bromo-2-(tetrahydrofuran-3-yl)pyrimidine chemical structure, C8H9BrN2O, CAS 1357580-22-3
5-Bromo-2-(tetrahydrofuran-3-yl)pyrimidine
CAS 1357580-22-3C8H9BrN2O
5-Methyl-2-(oxolan-3-yl)pyrimidine-4-carboxylic acid chemical structure, C10H12N2O3, CAS 1697923-03-7
5-Methyl-2-(oxolan-3-yl)pyrimidine-4-carboxylic acid
CAS 1697923-03-7C10H12N2O3
3-(Pyrimidin-2-yl)oxolan-3-amine chemical structure, C8H11N3O, CAS 1862606-64-1
3-(Pyrimidin-2-yl)oxolan-3-amine
CAS 1862606-64-1C8H11N3O
(2-(Tetrahydrofuran-3-yl)pyrimidin-5-yl)boronic acid chemical structure, C8H11BN2O3, CAS 2225153-41-1
(2-(Tetrahydrofuran-3-yl)pyrimidin-5-yl)boronic acid
CAS 2225153-41-1C8H11BN2O3
3-(Pyrimidin-2-yl)oxolan-3-amine hydrochloride chemical structure, C8H12ClN3O, CAS 2219419-45-9
3-(Pyrimidin-2-yl)oxolan-3-amine hydrochloride
CAS 2219419-45-9C8H12ClN3O
3-(Pyrimidin-2-yl)oxolan-3-amine dihydrochloride chemical structure, C8H13Cl2N3O, CAS 2193059-21-9
3-(Pyrimidin-2-yl)oxolan-3-amine dihydrochloride
CAS 2193059-21-9C8H13Cl2N3O
Ethyl 2-(oxolan-3-yl)pyrimidine-4-carboxylate chemical structure, C11H14N2O3, CAS 1691908-12-9
Ethyl 2-(oxolan-3-yl)pyrimidine-4-carboxylate
CAS 1691908-12-9C11H14N2O3
2-(2,5-Dimethyloxolan-3-yl)pyrimidine-4-carboxylic acid chemical structure, C11H14N2O3, CAS 2137664-54-9
2-(2,5-Dimethyloxolan-3-yl)pyrimidine-4-carboxylic acid
CAS 2137664-54-9C11H14N2O3
6-Chloro-2-(oxolan-3-yl)pyrimidine-4-carboxylic acid chemical structure, C9H9ClN2O3, CAS 2137817-78-6
6-Chloro-2-(oxolan-3-yl)pyrimidine-4-carboxylic acid
CAS 2137817-78-6C9H9ClN2O3
2-(2,2-Dimethyloxolan-3-yl)pyrimidine-4-carboxylic acid chemical structure, C11H14N2O3, CAS 2137538-62-4
2-(2,2-Dimethyloxolan-3-yl)pyrimidine-4-carboxylic acid
CAS 2137538-62-4C11H14N2O3