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Murcko scaffold

1-Phenylpyrrolidin-2-one scaffold

1,575 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
1,575
With full pages
234
Scaffold SMILES

O=C1CCCN1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenylpyrrolidin-2-one page
Murcko scaffold O=C1CCCN1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 1,575 chemicals

1-(3,4-Dichlorophenyl)-3-methylpyrrolidin-2-one chemical structure, C11H11Cl2NO, CAS 2860-64-2
1-(3,4-Dichlorophenyl)-3-methylpyrrolidin-2-one
CAS 2860-64-2C11H11Cl2NO
1-(3-Chloro-4-methylphenyl)-3-methylpyrrolidin-2-one chemical structure, C12H14ClNO, CAS 2884-69-7
1-(3-Chloro-4-methylphenyl)-3-methylpyrrolidin-2-one
CAS 2884-69-7C12H14ClNO
Iolidonic acid chemical structure, C15H16I3NO3, CAS 21766-53-0
Iolidonic acid
CAS 21766-53-0C15H16I3NO3
4-(Dimethylamino)-1-phenylpyrrolidin-2-one chemical structure, C12H16N2O, CAS 716-38-1
4-(Dimethylamino)-1-phenylpyrrolidin-2-one
CAS 716-38-1C12H16N2O
1-Phenylpyrrolidin-2-one chemical structure, C10H11NO, CAS 4641-57-0
1-Phenylpyrrolidin-2-one
CAS 4641-57-0C10H11NO
2-Pyrrolidinone, 1-(2-methylphenyl)- chemical structure, C11H13NO, CAS 24059-71-0
2-Pyrrolidinone, 1-(2-methylphenyl)-
CAS 24059-71-0C11H13NO
Flurochloridone chemical structure, C12H10Cl2F3NO, CAS 61213-25-0
Flurochloridone
CAS 61213-25-0C12H10Cl2F3NO
4-Amino-1-phenylpyrrolidin-2-one chemical structure, C10H12N2O, CAS 3026-59-3
4-Amino-1-phenylpyrrolidin-2-one
CAS 3026-59-3C10H12N2O
3-Amino-5-methyl-1-phenylpyrrolidin-2-one chemical structure, C11H14N2O, CAS 4915-39-3
3-Amino-5-methyl-1-phenylpyrrolidin-2-one
CAS 4915-39-3C11H14N2O
2-Pyrrolidinone, 3-amino-5-methyl-1-phenyl-, (Z)- chemical structure, C11H14N2O, CAS 4915-41-7
2-Pyrrolidinone, 3-amino-5-methyl-1-phenyl-, (Z)-
CAS 4915-41-7C11H14N2O
3-Amino-1-(4-fluorophenyl)pyrrolidin-2-one chemical structure, C10H11FN2O, CAS 5301-36-0
3-Amino-1-(4-fluorophenyl)pyrrolidin-2-one
CAS 5301-36-0C10H11FN2O
1-(4-Methoxyphenyl)-2-pyrrolidinone chemical structure, C11H13NO2, CAS 30425-47-9
1-(4-Methoxyphenyl)-2-pyrrolidinone
CAS 30425-47-9C11H13NO2
4-Aminomethyl-1-phenyl-2-pyrrolidinone chemical structure, C11H14N2O, CAS 148436-12-8
4-Aminomethyl-1-phenyl-2-pyrrolidinone
CAS 148436-12-8C11H14N2O
4-Aminomethyl-1-(4-methoxyphenyl)-2-pyrrolidinone chemical structure, C12H16N2O2, CAS 148436-13-9
4-Aminomethyl-1-(4-methoxyphenyl)-2-pyrrolidinone
CAS 148436-13-9C12H16N2O2
Orbofiban chemical structure, C17H23N5O4, CAS 163250-90-6
Orbofiban
CAS 163250-90-6C17H23N5O4
2-Pyrrolidinone, 1-(p-hydroxyphenyl)-, acetate (ester) chemical structure, C12H13NO3, CAS 14053-16-8
2-Pyrrolidinone, 1-(p-hydroxyphenyl)-, acetate (ester)
CAS 14053-16-8C12H13NO3
Benzenesulfonamide, 4-(2-oxo-1-pyrrolidinyl)- chemical structure, C10H12N2O3S, CAS 36090-27-4
Benzenesulfonamide, 4-(2-oxo-1-pyrrolidinyl)-
CAS 36090-27-4C10H12N2O3S
2-Pyrrolidinone, 4,4-dimethyl-1-(p-sulfamoylphenyl)- chemical structure, C12H16N2O3S, CAS 36090-29-6
2-Pyrrolidinone, 4,4-dimethyl-1-(p-sulfamoylphenyl)-
CAS 36090-29-6C12H16N2O3S
4-(4-Ethyl-4-methyl-2-oxopyrrolidin-1-yl)benzene-1-sulfonamide chemical structure, C13H18N2O3S, CAS 36090-33-2
4-(4-Ethyl-4-methyl-2-oxopyrrolidin-1-yl)benzene-1-sulfonamide
CAS 36090-33-2C13H18N2O3S
1-(4-Chlorophenyl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C11H10ClNO3, CAS 39629-87-3
1-(4-Chlorophenyl)-5-oxopyrrolidine-3-carboxylic acid
CAS 39629-87-3C11H10ClNO3
4-Pyrrolidinecarboxamide, N-(tert-butyl)-2-oxo-1-phenyl chemical structure, C15H20N2O2, CAS 39629-96-4
4-Pyrrolidinecarboxamide, N-(tert-butyl)-2-oxo-1-phenyl
CAS 39629-96-4C15H20N2O2
N-(3-(Dimethylamino)propyl)-5-oxo-1-phenyl-3-pyrrolidinecarboxamide chemical structure, C16H23N3O2, CAS 39629-97-5
N-(3-(Dimethylamino)propyl)-5-oxo-1-phenyl-3-pyrrolidinecarboxamide
CAS 39629-97-5C16H23N3O2
1-(4-Amino-2-methylphenyl)pyrrolidin-2-one chemical structure, C11H14N2O, CAS 13691-29-7
1-(4-Amino-2-methylphenyl)pyrrolidin-2-one
CAS 13691-29-7C11H14N2O
5-Methyl-1-phenylpyrrolidin-2-one chemical structure, C11H13NO, CAS 6724-71-6
5-Methyl-1-phenylpyrrolidin-2-one
CAS 6724-71-6C11H13NO